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Crisaborole intermediate

Product Name
Crisaborole intermediate
CAS No.
1187188-60-8
Chemical Name
Crisaborole intermediate
Synonyms
Crisaborole Impurity 28;Crisaborole Impurity 37;Crisaborole Impurity 59;5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol;Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
CBNumber
CB68131269
Molecular Formula
C14H13BO4
Formula Weight
256.06
MOL File
1187188-60-8.mol
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Crisaborole intermediate Property

Boiling point:
432.1±55.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
7.05±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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Crisaborole intermediate Chemical Properties,Usage,Production

Uses

5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.

Crisaborole intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Crisaborole intermediate Suppliers

Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
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View Lastest Price from Crisaborole intermediate manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Crisaborole Impurity 28 1187188-60-8
Price
US $0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-08

1187188-60-8, Crisaborole intermediateRelated Search:


  • 5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
  • Crisaborole Impurity 59
  • 5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol
  • Crisaborole Impurity 37
  • Crisaborole Impurity 28
  • Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
  • 1187188-60-8