ChemicalBook > CAS DataBase List > 8-BROMOQUINOLIN-2(1H)-ONE

8-BROMOQUINOLIN-2(1H)-ONE

Product Name
8-BROMOQUINOLIN-2(1H)-ONE
CAS No.
67805-67-8
Chemical Name
8-BROMOQUINOLIN-2(1H)-ONE
Synonyms
8-bromoquinolin-2-ol;8-Bromo-1H-quinolin-2-one;8-BROMOQUINOLIN-2(1H)-ONE;8-Bromo-2-hydroxyquinoline;8-BroMoquinoline-2(1h)-one;2(1H)-Quinolinone, 8-bromo-;8-Bromoquinolin-2(1H)-one98%;8-Bromoquinolin-2(1H)-one 98%;8-Bromo-1,2-dihydroquinolin-2-one;8-Bromo-1,2-dihydro-2-oxoquinoline
CBNumber
CB6828617
Molecular Formula
C9H6BrNO
Formula Weight
224.05
MOL File
67805-67-8.mol
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8-BROMOQUINOLIN-2(1H)-ONE Property

Melting point:
196-198 °C
Boiling point:
390.2±42.0 °C(Predicted)
Density 
1.620±0.06 g/cm3(Predicted)
storage temp. 
Room temperature.
pka
10.70±0.70(Predicted)
form 
Peachy beige fine crystalline needles
Appearance
Light yellow to light brown Solid
InChI
InChI=1S/C9H6BrNO/c10-7-3-1-2-6-4-5-8(12)11-9(6)7/h1-5H,(H,11,12)
InChIKey
HGJBIJWBYATVQY-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2Br)C=CC1=O
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Safety

HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
KOB0159
Product name
1-(2,3-Dihydro-1H-inden-2-yl)-2-methylpropan-2-amine hydrochloride
Packaging
1g
Price
$475
Updated
2025/07/31
TRC
Product number
B698938
Product name
8-Bromoquinolin-2(1H)-one
Packaging
1g
Price
$220
Updated
2021/12/16
TRC
Product number
B698938
Product name
8-Bromoquinolin-2(1H)-one
Packaging
100mg
Price
$50
Updated
2021/12/16
TRC
Product number
B698938
Product name
8-Bromoquinolin-2(1H)-one
Packaging
250mg
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
087219
Product name
8-Bromo-1,2-dihydroquinolin-2-one
Purity
>97%
Packaging
500mg
Price
$126
Updated
2021/12/16
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8-BROMOQUINOLIN-2(1H)-ONE Chemical Properties,Usage,Production

Uses

8-Bromoquinolin-2(1H)-one is an organic compound that inhibits the production of inflammatory substances in the body. It is a long-chain alkene and a synthetic substance that is used to prepare pharmaceuticals.

Application

8-Bromoquinolin-2(1H)-one has been shown to have anti-cancer properties, as well as an inhibitory effect on inflammation. The drug is synthesized by reacting benzonitrile with bromine and ammonia in a reaction system. 8-Bromoquinolin-2(1H)-one inhibits the synthesis of prostaglandin E2 (PGE2) by inhibiting cyclooxygenase and lipoxygenase enzymes. It also binds with high affinity to the enzyme phospholipase A 2 (PLA 2 ), which results in a rapid hydrolysis of phospholipids and production of arachidonic acid, which leads to increased levels of PGE2.

8-BROMOQUINOLIN-2(1H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMOQUINOLIN-2(1H)-ONE Suppliers

Nanjing Huarui Biopharmaceutical Technology Co., Ltd.
Tel
18014824111
Email
908320070@qq.com
Country
China
ProdList
65
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Shanghai Paulshine Chemical Co., Ltd.
Tel
+86-021-37788663
Fax
+86-021-37788663
Country
China
ProdList
186
Advantage
64
Wuhan Shangrisyn chemicals Technology Co.,Ltd
Tel
86-27-84466317 910021183
Fax
86-27-84466317
Country
China
ProdList
19
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62
Atop-Pharma (Shanghai) Technology Co., Ltd.
Tel
+86 (21) 5196-9732
Fax
+86 (21) 5196-9733
Country
China
ProdList
996
Advantage
57
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
1998
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
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View Lastest Price from 8-BROMOQUINOLIN-2(1H)-ONE manufacturers

Career Henan Chemical Co
Product
8-bromo-1H-quinolin-2-one 67805-67-8
Price
US $5.50/KG
Min. Order
1KG
Purity
98%min
Supply Ability
1kg,10kg,100kg
Release date
2020-01-09

67805-67-8, 8-BROMOQUINOLIN-2(1H)-ONERelated Search:


  • 8-BROMOQUINOLIN-2(1H)-ONE
  • 8-Bromo-1,2-dihydroquinolin-2-one
  • 8-bromoquinolin-2-ol
  • 8-Bromo-2-hydroxyquinoline
  • 8-Bromo-1,2-dihydro-2-oxoquinoline
  • 8-Bromoquinolin-2(1H)-one 98%
  • 8-BroMoquinoline-2(1h)-one
  • 8-Bromo-1H-quinolin-2-one
  • 8-Bromoquinolin-2(1H)-one98%
  • 2(1H)-Quinolinone, 8-bromo-
  • 1-(2,3-Dihydro-1<i>H</i>-inden-2-yl)-2-methylpropan-2-amine hydrochloride
  • 8-bromo-1,2-dihydroquinolin-2-one - [B87231]
  • 67805-67-8