ChemicalBook > CAS DataBase List > 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE

2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE

Product Name
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
CAS No.
41179-33-3
Chemical Name
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
Synonyms
CMPD-1;CMD1;SRA1;MK2a Inhibitor;CMPD-1 (CMPD 1;Steroid receptor RNA activator 1;ANTI-SOX9 antibody produced in mouse;MK2a Inhibitor - CAS 41179-33-3 - Calbiochem;ANTI-SRA1 (C-TERM) antibody produced in rabbit;Monoclonal Anti-SOX9 antibody produced in mouse
CBNumber
CB6840374
Molecular Formula
C22H20FNO2
Formula Weight
349.4
MOL File
41179-33-3.mol
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2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Property

Melting point:
128-130 °C
Boiling point:
585.0±50.0 °C(Predicted)
Density 
1.229±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Pale yellow solid
pka
10.11±0.26(Predicted)
color 
Off-white to light brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
AMAB90795
Product name
Monoclonal Anti-SOX9 antibody produced in mouse
Purity
Prestige Antibodies? Powered by Atlas Antibodies, clone CL0639, purified immunoglobulin, buffered aqueous glycerol solution
Packaging
25μL
Price
$294
Updated
2024/03/01
Sigma-Aldrich
Product number
WH0006662M2
Product name
Monoclonal Anti-SOX9 antibody produced in mouse
Purity
clone 3C10, purified immunoglobulin, buffered aqueous solution
Packaging
100μG
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
AMAB90795
Product name
Monoclonal Anti-SOX9 antibody produced in mouse
Purity
Prestige Antibodies? Powered by Atlas Antibodies, clone CL0639, purified immunoglobulin, buffered aqueous glycerol solution
Packaging
100μL
Price
$514
Updated
2024/03/01
Sigma-Aldrich
Product number
475863
Product name
MK2a Inhibitor - CAS 41179-33-3 - Calbiochem
Packaging
5mg
Price
$318
Updated
2024/03/01
Cayman Chemical
Product number
17325
Product name
MK2a Inhibitor
Packaging
5mg
Price
$116
Updated
2024/03/01
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2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Chemical Properties,Usage,Production

Uses

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Uses

Monoclonal Anti-SOX9 antibody produced in mouse has been used in immunofluorescence.

Definition

ChEBI: 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide is a member of biphenyls.

General Description

Sex determining region Y box 9 (Sox9) is a transcription protein, that belongs to the high-mobility-group box class DNA-binding proteins. It is located on human chromosome 17q24.

Biological Activity

Non-ATP-competitive, selective inhibitor of p38 α -mediated MK2a (mitogen-activated protein kinase-activated protein kinase 2a) phosphorylation (apparent K i = 330 nM). Does not inhibit p38 α -mediated phosphorylation of the two other known p38 substrates, MBP and ATF-2.

Biochem/physiol Actions

Sex determining region Y box 9 (Sox9) participates in the human development processes. It helps to maintain the pluripotent cells at the time of pancreatic organogenesis. In adult tissues, Sox9 modulates stem and progenitor cells. Haploinsufficiency of Sox9 results in campomelic dysplasia (CD), a disease characterized by bowed femurs and tibiae, hypoplastic scapulae, 11 pairs of ribs, pelvic malformations, Robin sequence and clubbed feet.

storage

Store at RT

2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Suppliers

EMMX Biotechnology LLC
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41179-33-3, 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDERelated Search:


  • 4-(2'-FLUOROBIPHENYL-4-YL)-N-(4-HYDROXYPHENYL)-BUTYRAMIDE
  • 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
  • CMPD-1
  • ANTI-SRA1 (C-TERM) antibody produced in rabbit
  • Steroid receptor RNA activator 1
  • CMD1
  • Monoclonal Anti-SOX9 antibody produced in mouse
  • SRA1
  • ANTI-SOX9 antibody produced in mouse
  • MK2a Inhibitor
  • 4-(2'-fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide
  • CMPD-1 (CMPD 1
  • MK2a Inhibitor - CAS 41179-33-3 - Calbiochem
  • [1,1'-Biphenyl]-4-butanamide, 2'-fluoro-N-(4-hydroxyphenyl)-
  • MAPK activated protein kinase 2,MAP kinase activated protein kinase 2,CMPD 1,MAPKAPK2 (MK2),inhibit,Mitogen-activated protein kinase activated protein kinase 2,Inhibitor,CMPD-1,CMPD1,MAPKAP kinase 2
  • 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
  • 4-(2'-Fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide
  • 41179-33-3
  • Protein Kinase