ChemicalBook > CAS DataBase List > B-D-GLUCOPYRANOSE

B-D-GLUCOPYRANOSE

Product Name
B-D-GLUCOPYRANOSE
CAS No.
60976-49-0
Chemical Name
B-D-GLUCOPYRANOSE
Synonyms
7:4®eraniin;GERANIIN;geranicin;Geraniin-RM;B-D-GLUCOPYRANOSE;b-D-Glucopyranose, cyclic 2®3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-penta...;Geraniin,Tumor Necrosis Factor Receptor,inhibit,TNF Receptor,Inhibitor,TNFR;5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-Methano-2H-1-benzoxocin-5,7-dicarboxylate)cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate)1-(3,4,5-trihydroxybenzoate), stereoisoMer
CBNumber
CB6848749
Molecular Formula
C41H28O27
Formula Weight
952.64
MOL File
60976-49-0.mol
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B-D-GLUCOPYRANOSE Property

Density 
2.25
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO : 100 mg/mL (104.97 mM; Need ultrasonic)
form 
powder
pka
6.35±0.70(Predicted)
color 
Light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80994
Product name
Geraniin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$526
Updated
2024/03/01
Cayman Chemical
Product number
29924
Product name
Geraniin
Packaging
5mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
29924
Product name
Geraniin
Packaging
50mg
Price
$957
Updated
2024/03/01
Cayman Chemical
Product number
29924
Product name
Geraniin
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
29924
Product name
Geraniin
Packaging
10mg
Price
$214
Updated
2024/03/01
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B-D-GLUCOPYRANOSE Chemical Properties,Usage,Production

Description

Geraniin is a tannin that has been found in P. urinaria and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; IC50s = 0.92 and 1.27 μM at pH 4.5 and 7.9, respectively), superoxide (IC50 = 2.65 μM), and hydroxyl radicals (IC50 = 1.44 μM) in cell-free assays. Geraniin inhibits herpes simplex virus 1 (HSV-1) and HSV-2 replication in plaque reduction assays (IC50s = 35 and 18.4 μM, respectively). It inhibits angiotensin-converting enzyme (ACE) in vitro (IC50 = 13.22 μM) and reduces both systolic and diastolic blood pressure in spontaneously hypertensive rats when administered at a dose of 5 mg/kg. Geraniin (5, 10, and 20 μM) induces apoptosis and halts the cell cycle at the S phase in A549 lung cancer cells. It reduces tumor growth in an A549 mouse xenograft model when administered at doses of 10 and 20 mg/kg.

Uses

Geraniin protects PC12 cells against neuronal damage and may be used in the treatment of Alzheimer’s disease/ Also is an ACE inhibitor which is useful for hypertension treatment.

Definition

ChEBI: Geraniin is a tannin.

B-D-GLUCOPYRANOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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B-D-GLUCOPYRANOSE Suppliers

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View Lastest Price from B-D-GLUCOPYRANOSE manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Geraniin 60976-49-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-01-02
Career Henan Chemical Co
Product
Geraniin 60976-49-0
Price
US $2.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
100kg
Release date
2019-12-20

60976-49-0, B-D-GLUCOPYRANOSERelated Search:

Diphenic acid alpha-D-Glucose pentaacetate B-D-GLUCOPYRANOSE 2-(2-METHOXYETHOXY)ETHYL METHACRYLATE CORILAGIN 2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSE 3-O-METHYL-ALPHA-D-GLUCOPYRANOSE,3-O-METHYL-D-GLUCOPYRANOSE Streptozotocin 2-DEOXY-2-SULFAMINO-D-GLUCOPYRANOSE SODIUM SALT 2-O-BETA-D-GLUCOPYRANOSYL-D-GLUCOPYRANOSE 2-DEOXY-2-VALERAMIDO-D-GLUCOPYRANOSE,2-DEOXY-2-PENTANAMIDO-D-GLUCOPYRANOSE 3-O-METHYL-D-GLUCOPYRANOSE 2-DEOXY-2-HEXANAMIDO-D-GLUCOPYRANOSE 1,2,3,4,6-PENTA-O-ACETYL-A-GLUCOPYRANOSE DIETHYLENE GLYCOL MONO-METHACRYLATE 1,2,3,6-Tetra-O-benzyl-b-D-glucopyranoside BIPHENYL-2,2'-DICARBOXYLIC ACID DIMETHYL ESTER 2-(3-OXO-PROPYL)-BENZOIC ACID METHYL ESTER

  • eraniin
  • GERANIIN
  • B-D-GLUCOPYRANOSE
  • beta-D-Glucopyranose cyclic 2-7:4-5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate) stereoisomer
  • 3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-11H-3,5-epoxy-25,11-(epoxymethano)dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododecin-29-yl 3,4,5-trihydroxybenzoat
  • 5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-Methano-2H-1-benzoxocin-5,7-dicarboxylate)cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate)1-(3,4,5-trihydroxybenzoate), stereoisoMer
  • 7:4&reg
  • b-D-Glucopyranose, cyclic 2&reg
  • β-D-Glucopyranose, cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), stereoisomer
  • 3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-penta...
  • Geraniin,Tumor Necrosis Factor Receptor,inhibit,TNF Receptor,Inhibitor,TNFR
  • geranicin
  • (57R,58S,510R,511R,519S)-14,15,16,24,25,26,52,53,516,517,517-Undecahydroxy-55,513,515,3,8-pentaoxo-55,57,58,510,511,513,515,516,517,517a-decahydro-4,7-dioxa-5(19,10)-1,16-epoxy-7,11-methanodibenzo[i,k][1,4,7]trioxacyclotridecina-1,2(1,2)-dibenzenacyclooctaphane-58-yl 3,4,5-trihydroxybenzoate
  • Geraniin-RM
  • 60976-49-0
  • C41H28O27
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract