B-D-GLUCOPYRANOSE

ChemicalBook > CAS DataBase List > B-D-GLUCOPYRANOSE

Product Name: B-D-GLUCOPYRANOSE
CAS No.: 60976-49-0
Chemical Name: B-D-GLUCOPYRANOSE
Synonyms: 7:4®eraniin;GERANIIN;geranicin;B-D-GLUCOPYRANOSE;b-D-Glucopyranose, cyclic 2®3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-penta...;Geraniin,Tumor Necrosis Factor Receptor,inhibit,TNF Receptor,Inhibitor,TNFR;5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-Methano-2H-1-benzoxocin-5,7-dicarboxylate)cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate)1-(3,4,5-trihydroxybenzoate), stereoisoMer;β-D-Glucopyranose, cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), stereoisomer
CBNumber: CB6848749
Molecular Formula: C41H28O27
Formula Weight: 952.64
MOL File: 60976-49-0.mol

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B-D-GLUCOPYRANOSE Property

Density: 2.25
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO : 100 mg/mL (104.97 mM; Need ultrasonic)
form: powder
pka: 6.35±0.70(Predicted)
color: Light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL80994
Product name: Geraniin
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $526
Updated: 2024/03/01

Cayman Chemical

Product number: 29924
Product name: Geraniin
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 29924
Product name: Geraniin
Packaging: 50mg
Price: $957
Updated: 2024/03/01

Cayman Chemical

Product number: 29924
Product name: Geraniin
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 29924
Product name: Geraniin
Packaging: 10mg
Price: $214
Updated: 2024/03/01

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B-D-GLUCOPYRANOSE Chemical Properties,Usage,Production

Description

Geraniin is a tannin that has been found in P. urinaria and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; IC₅₀s = 0.92 and 1.27 μM at pH 4.5 and 7.9, respectively), superoxide (IC₅₀ = 2.65 μM), and hydroxyl radicals (IC₅₀ = 1.44 μM) in cell-free assays. Geraniin inhibits herpes simplex virus 1 (HSV-1) and HSV-2 replication in plaque reduction assays (IC₅₀s = 35 and 18.4 μM, respectively). It inhibits angiotensin-converting enzyme (ACE) in vitro (IC₅₀ = 13.22 μM) and reduces both systolic and diastolic blood pressure in spontaneously hypertensive rats when administered at a dose of 5 mg/kg. Geraniin (5, 10, and 20 μM) induces apoptosis and halts the cell cycle at the S phase in A549 lung cancer cells. It reduces tumor growth in an A549 mouse xenograft model when administered at doses of 10 and 20 mg/kg.

Uses

Geraniin protects PC12 cells against neuronal damage and may be used in the treatment of Alzheimer’s disease/ Also is an ACE inhibitor which is useful for hypertension treatment.

Definition

ChEBI: Geraniin is a tannin.

B-D-GLUCOPYRANOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from B-D-GLUCOPYRANOSE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Geraniin 60976-49-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-01-02

Career Henan Chemical Co

Product: Geraniin 60976-49-0
Price: US $2.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 100kg
Release date: 2019-12-20

60976-49-0, B-D-GLUCOPYRANOSERelated Search:

Diphenic acid alpha-D-Glucose pentaacetate B-D-GLUCOPYRANOSE 2-(2-METHOXYETHOXY)ETHYL METHACRYLATE CORILAGIN 2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSE 3-O-METHYL-ALPHA-D-GLUCOPYRANOSE,3-O-METHYL-D-GLUCOPYRANOSE Streptozotocin 2-DEOXY-2-SULFAMINO-D-GLUCOPYRANOSE SODIUM SALT 2-O-BETA-D-GLUCOPYRANOSYL-D-GLUCOPYRANOSE 2-DEOXY-2-VALERAMIDO-D-GLUCOPYRANOSE,2-DEOXY-2-PENTANAMIDO-D-GLUCOPYRANOSE 3-O-METHYL-D-GLUCOPYRANOSE 2-DEOXY-2-HEXANAMIDO-D-GLUCOPYRANOSE 1,2,3,4,6-PENTA-O-ACETYL-A-GLUCOPYRANOSE DIETHYLENE GLYCOL MONO-METHACRYLATE 1,2,3,6-Tetra-O-benzyl-b-D-glucopyranoside BIPHENYL-2,2'-DICARBOXYLIC ACID DIMETHYL ESTER 2-(3-OXO-PROPYL)-BENZOIC ACID METHYL ESTER

eraniin

GERANIIN

B-D-GLUCOPYRANOSE

beta-D-Glucopyranose cyclic 2-7:4-5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate) stereoisomer

3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-pentaoxo-2,3,4,4a,9,11a,13,22,24,25,25a,27-dodecahydro-11H-3,5-epoxy-25,11-(epoxymethano)dibenzo[h,j]dibenzo[7,8:9,10][1,5]dioxacycloundecino[3,2-b][1,6]dioxacyclododecin-29-yl 3,4,5-trihydroxybenzoat

5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-Methano-2H-1-benzoxocin-5,7-dicarboxylate)cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate)1-(3,4,5-trihydroxybenzoate), stereoisoMer

7:4&reg

b-D-Glucopyranose, cyclic 2&reg

β-D-Glucopyranose, cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), stereoisomer

3,4,4,6,7,15,16,17,18,19,20-undecahydroxy-2,9,13,22,27-penta...

Geraniin,Tumor Necrosis Factor Receptor,inhibit,TNF Receptor,Inhibitor,TNFR

geranicin

(57R,58S,510R,511R,519S)-14,15,16,24,25,26,52,53,516,517,517-Undecahydroxy-55,513,515,3,8-pentaoxo-55,57,58,510,511,513,515,516,517,517a-decahydro-4,7-dioxa-5(19,10)-1,16-epoxy-7,11-methanodibenzo[i,k][1,4,7]trioxacyclotridecina-1,2(1,2)-dibenzenacyclooctaphane-58-yl 3,4,5-trihydroxybenzoate

60976-49-0

C41H28O27

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract