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Diphenic acid

Description Sources
Product Name
Diphenic acid
CAS No.
482-05-3
Chemical Name
Diphenic acid
Synonyms
O-PHENYL BENZOIC ACID;Diphenic;BIPHENIC ACID;2,2?Diphenit acid;[1,1'-BIPHENYL]-2,2'-DICARBOXYLIC ACID;iphenicaci;DIPHENIC ACID;O-DIPHENIC ACID;2,2-United acid;Diphenicacid,96%
CBNumber
CB6425276
Molecular Formula
C14H10O4
Formula Weight
242.23
MOL File
482-05-3.mol
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Diphenic acid Property

Melting point:
227-229 °C(lit.)
Boiling point:
345.05°C (rough estimate)
Density 
1.2695 (rough estimate)
refractive index 
1.5389 (estimate)
storage temp. 
Store below +30°C.
solubility 
almost transparency in Methanol
form 
powder to crystal
pka
pKa 3.20(H2O t=23.0) (Uncertain);5.06(H2O t=23.0) (Uncertain)
color 
White to Orange to Green
PH
4-5 (H2O, 20℃)
Water Solubility 
insoluble (20 ºC)
Merck 
14,3310
BRN 
2053625
InChIKey
GWZCCUDJHOGOSO-UHFFFAOYSA-N
CAS DataBase Reference
482-05-3(CAS DataBase Reference)
NIST Chemistry Reference
2,2'-Biphenyldicarboxylic acid(482-05-3)
EPA Substance Registry System
[1,1'-Biphenyl]-2,2'-dicarboxylic acid (482-05-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-37
WGK Germany 
3
Autoignition Temperature
390 °C
TSCA 
Yes
HS Code 
29173980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
126691
Product name
Diphenic acid
Purity
97%
Packaging
25g
Price
$83.4
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02256
Product name
2,2′-Biphenyldicarboxylic acid
Purity
for synthesis
Packaging
50G
Price
$136
Updated
2024/03/01
Sigma-Aldrich
Product number
126691
Product name
Diphenic acid
Purity
97%
Packaging
100g
Price
$336
Updated
2024/03/01
TCI Chemical
Product number
D0864
Product name
2,2'-Biphenyldicarboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$292
Updated
2024/03/01
TCI Chemical
Product number
D0864
Product name
2,2'-Biphenyldicarboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$870
Updated
2024/03/01
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Diphenic acid Chemical Properties,Usage,Production

Description

2,2’Dicarboxybiphenyl acid is also known as diphenic acid, being a useful pharmaceutical intermediate and used in the synthesis of dyes. Diphenic acid derivatives have attracted great attention due to its possession of useful therapeutic properties. Many diphenic acids derivatives have the potential of lowering the risk of chronic diseases such as cancer, cardiovascular diseases and other pathologies. It is applied in many herbs and components of food. Diphenic acids derivatives can usually be found in fruits like blackberry, raspberry and strawberry.

Sources

https://www.alfa.com/zh-cn/catalog/A15863/
https://www.tandfonline.com/doi/abs/10.1080/00397911.2017.1298805?journalCode=lsyc20

Chemical Properties

Off-white powder

Definition

ChEBI: Diphenic acid is a dicarboxylic acid. It is a conjugate acid of a diphenate(1-). It derives from a hydride of a biphenyl.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 2876, 1960 DOI: 10.1021/ja01496a051
Organic Syntheses, Coll. Vol. 1, p. 222, 1941
Synthesis, p. 731, 1982

Purification Methods

Crystallise diphenic acid from water. Hot Ac2O provides the anhydride below. [Beilstein 9 H 922, 9 IV 3552.]

Diphenic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Diphenic acid Suppliers

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
667
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Dr. J. Pharmachem (India)
Tel
+91 20 24332987
Fax
+91 20 24332137
Email
info@jpharmachem.com
Country
India
ProdList
97
Advantage
55
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from Diphenic acid manufacturers

Shanghai UCHEM Inc.
Product
2,2'-Biphenyldicarboxylic acid 482-05-3
Price
US $24.00-336.00/g
Min. Order
25g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-08
Hebei Chuanghai Biotechnology Co,.LTD
Product
Diphenic acid 482-05-3
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
Henan Aochuang Chemical Co.,Ltd.
Product
Diphenic acid 482-05-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-16

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