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Diphenic acid

Description Sources
Product Name
Diphenic acid
CAS No.
482-05-3
Chemical Name
Diphenic acid
Synonyms
O-PHENYL BENZOIC ACID;Diphenic;BIPHENIC ACID;2,2?Diphenit acid;[1,1'-BIPHENYL]-2,2'-DICARBOXYLIC ACID;iphenicaci;DIPHENIC ACID;O-DIPHENIC ACID;2,2-United acid;Diphenicacid,96%
CBNumber
CB6425276
Molecular Formula
C14H10O4
Formula Weight
242.23
MOL File
482-05-3.mol
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Diphenic acid Property

Melting point:
227-229 °C(lit.)
Boiling point:
345.05°C (rough estimate)
Density 
1.2695 (rough estimate)
refractive index 
1.5389 (estimate)
storage temp. 
Store below +30°C.
solubility 
almost transparency in Methanol
form 
powder to crystal
pka
pKa 3.20(H2O t=23.0) (Uncertain);5.06(H2O t=23.0) (Uncertain)
color 
White to Orange to Green
PH
4-5 (H2O, 20℃)
Water Solubility 
insoluble (20 ºC)
Merck 
14,3310
BRN 
2053625
InChIKey
GWZCCUDJHOGOSO-UHFFFAOYSA-N
CAS DataBase Reference
482-05-3(CAS DataBase Reference)
NIST Chemistry Reference
2,2'-Biphenyldicarboxylic acid(482-05-3)
EPA Substance Registry System
[1,1'-Biphenyl]-2,2'-dicarboxylic acid (482-05-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-37
WGK Germany 
3
Autoignition Temperature
390 °C
TSCA 
Yes
HS Code 
29173980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
126691
Product name
Diphenic acid
Purity
97%
Packaging
25g
Price
$83.4
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02256
Product name
2,2′-Biphenyldicarboxylic acid
Purity
for synthesis
Packaging
50G
Price
$136
Updated
2024/03/01
Sigma-Aldrich
Product number
126691
Product name
Diphenic acid
Purity
97%
Packaging
100g
Price
$336
Updated
2024/03/01
TCI Chemical
Product number
D0864
Product name
2,2'-Biphenyldicarboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$292
Updated
2024/03/01
TCI Chemical
Product number
D0864
Product name
2,2'-Biphenyldicarboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$870
Updated
2024/03/01
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Diphenic acid Chemical Properties,Usage,Production

Description

2,2’Dicarboxybiphenyl acid is also known as diphenic acid, being a useful pharmaceutical intermediate and used in the synthesis of dyes. Diphenic acid derivatives have attracted great attention due to its possession of useful therapeutic properties. Many diphenic acids derivatives have the potential of lowering the risk of chronic diseases such as cancer, cardiovascular diseases and other pathologies. It is applied in many herbs and components of food. Diphenic acids derivatives can usually be found in fruits like blackberry, raspberry and strawberry.

Sources

https://www.alfa.com/zh-cn/catalog/A15863/
https://www.tandfonline.com/doi/abs/10.1080/00397911.2017.1298805?journalCode=lsyc20

Chemical Properties

Off-white powder

Definition

ChEBI: Diphenic acid is a dicarboxylic acid. It is a conjugate acid of a diphenate(1-). It derives from a hydride of a biphenyl.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 2876, 1960 DOI: 10.1021/ja01496a051
Organic Syntheses, Coll. Vol. 1, p. 222, 1941
Synthesis, p. 731, 1982

Purification Methods

Crystallise diphenic acid from water. Hot Ac2O provides the anhydride below. [Beilstein 9 H 922, 9 IV 3552.]

Diphenic acid Preparation Products And Raw materials

Raw materials

Phenanthrene

Preparation Products

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Diphenic acid Suppliers

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View Lastest Price from Diphenic acid manufacturers

Shanghai UCHEM Inc.
Product
2,2'-Biphenyldicarboxylic acid 482-05-3
Price
US $24.00-336.00/g
Min. Order
25g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-08
Hebei Guanlang Biotechnology Co,.LTD
Product
Diphenic acid 482-05-3
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2023-03-23
Henan Aochuang Chemical Co.,Ltd.
Product
Diphenic acid 482-05-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-16

482-05-3, Diphenic acidRelated Search:

Diethyl phthalate Potassium hydrogen phthalate Terephthalic acid Folic acid Dimethyl phthalate Citric acid Phthalic acid Isophthalic acid Diisobutyl phthalate Bis(2-ethylhexyl) phthalate 4,4'-Bis(methoxymethyl)-1,1'-biphenyl Dibutyl phthalate Hyaluronic acid Biphenyl Ethyl 2-(Chlorosulfonyl)acetate OXALIC ACID Ascoric Acid CHARTREUSIN

  • 2,2'-DIPHENIC ACID
  • 2,2'-DIPHENYLDICARBOXYLIC ACID
  • 2,2'-DICARBOXYBIPHENYL
  • 2,2'-DICARBOXY DIPHENYL
  • 2,2'-BIPHENYLDICARBOXYLIC ACID
  • 2,2'-BIBENZOIC ACID
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  • BIPHENYL-2,2'-DICARBOXYLIC ACID
  • BIPHENIC ACID
  • DIPHENYL-2,2'-DICARBOXYLIC ACID
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  • O-PHENYL BENZOIC ACID
  • O,O'-DIPHENIC ACID
  • 2,2?Diphenit acid
  • Diphenicacid,96%
  • Diphenic
  • 2,2''-BIPHENYLDICARBOXYLIC ACID / DIPHENIC ACID
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  • Diphenic acid, 96% 25GR
  • 2,2'-Bibenzoic Acid 2,2'-Dicarboxybiphenyl Diphenic Acid
  • 2,2'-BIPHENYLDICARBOXYLIC ACID FOR SYNTH
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  • 2,2-diphenyltwocarboxylic acid
  • biphenyl-2,2'-dicarboxylate
  • Diphenic acid 97%
  • 2,2'-Biphenyldicarboxylic acid for synthesis
  • [1,1'-Biphenyl]-2,2'-dicarboxylic acid 97%
  • 2-phenylcyclohexa-2,4-diene-1,1-dicarboxylic acid
  • 2,2'-Biphenyldicarboxylic Acid &gt
  • Diphenic Acid,>98%
  • iphenicaci
  • Diphenic Acid (Biphenyl-2,2'dicarboxylic Acid) (Stellar-2008)
  • Diphenic acid (6CI, 8CI)
  • 2,2'-Biphenyldicarboxylic Acid
  • 1,1'-Biphenyl]-2,2'-dicarboxylic acid
  • 2,2'-Bibenzoic acid
  • 482-05-3
  • 128-97-0
  • 482-05-03
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  • C6H5C6H4COOH
  • 2HO2CC6H4C6H42CO2H
  • Organic Building Blocks
  • Building Blocks
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  • Carboxylic Acids
  • C13 to C42+
  • Reagent for High-Performance Polymer Research
  • Biphenyls (for High-Performance Polymer Research)
  • Biphenyl series
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts