1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR

Product Name: 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR
CAS No.: 59839-23-5
Chemical Name: 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR
Synonyms: RMA-192;1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR;6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR;1,2,3,4-tetrahydroisoquinolin-6-ol, HBr salt;1,2,3,4-Tetrahydro-iso-6-hydroxy-quinoline HBr;1,2,3,4-Tetrahydro iso-6-hydroxy-quinoline HBr;1,2,3,4-Tetrahydroisoquinolin-6-olhydrobrimide;l,2,3,4-Tetrahydro-6-isoquinolinol Hydrobromide;1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HYDROBROMIDE;6-Isoquinolinol,1,2,3,4-tetrahydro-,hydrobromide
CBNumber: CB6849403
Molecular Formula: C9H12BrNO
Formula Weight: 230.10168
MOL File: 59839-23-5.mol

More

Less

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR Property

Melting point:: 196.7-197.8℃
storage temp.: Inert atmosphere,Room Temperature
Appearance: White to off-white Solid

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933491090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: T293975
Product name: 1,2,3,4-Tetrahydro-6-isoquinolin-6-olHydrobromide
Packaging: 50mg
Price: $55
Updated: 2021/12/16

TRC

Product number: T293975
Product name: 1,2,3,4-Tetrahydro-6-isoquinolin-6-olHydrobromide
Packaging: 2.5g
Price: $495
Updated: 2021/12/16

Ark Pharm

Product number: P000105051
Product name: 1,2,3,4-Tetrahydroisoquinolin-6-ol hydrobrimide
Purity: 97%
Packaging: 1g
Price: $131
Updated: 2021/12/16

Ark Pharm

Product number: P000105051
Product name: 1,2,3,4-Tetrahydroisoquinolin-6-ol hydrobrimide
Purity: 97%
Packaging: 5g
Price: $401
Updated: 2021/12/16

Matrix Scientific

Product number: 074026
Product name: 1,2,3,4-Tetrahydroisoquinolin-6-ol hydrobromide
Purity: 95+%
Packaging: 500mg
Price: $200
Updated: 2021/12/16

More

Less

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR Chemical Properties,Usage,Production

Uses

1,2,3,4-Tetrahydro-6-isoquinolin-6-ol Hydrobromide is a chemical reagent used in the organic synthesis. Used in the preparation of androgen receptor modulators (SARMs) as well as steroidmimetic and chimeric microtubule disruptors.

Synthesis

42923-77-3

59839-23-5

General procedure for the synthesis of 1,2,3,4-tetrahydroisoquinolin-6-ol hydrobromide from 6-methoxy-1,2,3,4-tetrahydroisoquinoline: 6-methoxy-1,2,3,4-tetrahydroisoquinoline (2.12 g, 13.0 mmol) was dissolved in 48% aqueous hydrobromic acid. The reaction mixture was stirred at 120°C for 3 hours. After completion of the reaction, the solvent was removed by vacuum concentration. The obtained residue was suspended in ethyl acetate and the solvent was evaporated again to afford 1,2,3,4-tetrahydroisoquinolin-6-ol hydrobromide (2.99 g, 95% yield) as a reddish brown solid. The product was characterized by 1H NMR (300 MHz, D2O): δ 7.10 (d, J = 8.4 Hz, 1H), 6.82-6.75 (m, 2H), 4.28 (s, 2H), 3.48 (t, J = 6.3 Hz, 2H), 3.05 (t, J = 6.3 Hz, 2H).

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 4, p. 789 - 801
[2] Journal of Medicinal Chemistry, 1987, vol. 30, # 12, p. 2208 - 2216
[3] Patent: US6562828, 2003, B1
[4] Patent: US5936089, 1999, A
[5] Patent: WO2007/146122, 2007, A2. Location in patent: Page/Page column 42

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR Suppliers

China 51 India 3 United Kingdom 1 United States 11 Global 66

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Modachem Shanghai Co., Ltd

Tel: +86 (0)21 51320687 51371369 1744605818
Fax: +86 (0)21 51371369
Country: China
ProdList: 1578
Advantage: 58

Shanghai PharmOrgsyn Technology Co., LTD.

Tel: 021-+86-021-38228826 13916602830;
Fax: sales@pharmorgsyn.com
Email: sales@pharmorgsyn.cn
Country: China
ProdList: 242
Advantage: 58

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

More

Less

View Lastest Price from 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR manufacturers

Career Henan Chemical Co

Product: 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR 59839-23-5
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-10

59839-23-5, 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBRRelated Search:

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL Isoquinolin-6-ol DL-LAUDANOSOLINE HYDROBROMIDE TRIHYDRATE (+/-)-TETRAHYDROPAPAVEROLINE HYDROBROMIDE 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE (-)-BICUCULLINE METHOBROMIDE DL-6'-BROMOLAUDANOSIN 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR 6,7-DIHYDROXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE EMETINE HYDROBROMIDE HYDROCOTARNINE HYDROBROMIDE 1-(2-BROMO-4,5-DIMETHOXYPHENYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE CBI-BB ZERO/003104 R(-)-2,10,11-TRIHYDROXYAPORPHINE HYDROBROMIDE R(-)-2,10,11-TRIHYDROXY-N-PROPYL-NORAPORPHINE HYDROBROMIDE LYCORINE HYDROBROMIDE 6,7-Dihydroxy-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide (1R)-6,7-DIHYDROXY-1,2-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROBROMIDE

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HBR

1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL HYDROBROMIDE

1,2,3,4-Tetrahydroisoquinolin-6-olhydrobrimide

l,2,3,4-Tetrahydro-6-isoquinolinol Hydrobromide

6-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HBR

1,2,3,4-tetrahydro-6-hydroxy-isoquinoline-hydrobroMide

6-Hydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide

1,2,3,4-Tetrahydro iso-6-hydroxy-quinoline HBr

1,2,3,4-Tetrahydro-iso-6-hydroxy-quinoline HBr

6-Isoquinolinol,1,2,3,4-tetrahydro-,hydrobromide

1,2,3,4-Tetrahydro-6-isoquinolinol (hydrobromide)

1,2,3,4-tetrahydroisoquinolin-6-ol, HBr salt

1,2,3,4-tetrahydroisoquinolin-6-ol hydrobromide (1:1)

RMA-192

59839-23-5

C9H11NOHBr

C9H11NOBrH

Quinoline&Isoquinoline