AMN082 DIHYDROCHLORIDE
- Product Name
- AMN082 DIHYDROCHLORIDE
- CAS No.
- 83027-13-8
- Chemical Name
- AMN082 DIHYDROCHLORIDE
- Synonyms
- AMN 082;AMN082 free base;AMN 082 dihydrochlor;AMN082 DIHYDROCHLORIDE;N,N'-bis(diphenylMethyl)ethylenediaMine;1,2-Ethanediamine, N1,N2-bis(diphenylmethyl)-;N,N'-DIBENZHYDRYLETHANE-1,2-DIAMINE DIHYDROCHLORIDE;N,N'-Bis(diphenylmethyl)-1,2-ethandiamine dihydrochloride;N,N'-BIS(DIPHENYLMETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE;locomotor,allosteric,AMN082 free base,AMN 082,blood-brain,stress,hormone,Inhibitor,AMN-082,inhibit,sensitization,AMN-082 free base,oral,Metabotropic glutamate receptors,mGluR,barrier
- CBNumber
- CB6849458
- Molecular Formula
- C28H28N2
- Formula Weight
- 392.54
- MOL File
- 83027-13-8.mol
AMN082 DIHYDROCHLORIDE Property
- Melting point:
- 105.5 °C
- Boiling point:
- 533.7±45.0 °C(Predicted)
- Density
- 1.086±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- DMSO : 12.5 mg/mL (31.84 mM; ultrasonic and warming and heat to 60°C)
- pka
- 8.38±0.29(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 2385
- Product name
- AMN082dihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $124
- Updated
- 2021/12/16
- Product number
- 2385
- Product name
- AMN082dihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $521
- Updated
- 2021/12/16
- Product number
- 254625
- Product name
- AMN 082 dihydrochloride
- Packaging
- 10mg
- Price
- $366
- Updated
- 2021/12/16
- Product number
- BIO0000325
- Product name
- AMN-082
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.74
- Updated
- 2021/12/16
AMN082 DIHYDROCHLORIDE Chemical Properties,Usage,Production
Uses
AMN082 dihydrochloride is a selective agonist at mGluR-7.
Definition
ChEBI: N,N'-bis(diphenylmethyl)ethane-1,2-diamine is a diamine that is ethane-1,2-diamine in which both amino groups are substituted by diphenylmethyl groups. It is an allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7). It has a role as a metabotropic glutamate receptor agonist and a neuroprotective agent. It is a diarylmethane, a secondary amino compound, a diamine and a member of benzenes. It is a conjugate base of a N,N'-bis(diphenylmethyl)ethane-1,2-diamine(2+).
Biological Activity
The first selective mGlu 7 agonist. Potently inhibits cAMP accumulation and stimulates GTP γ S binding in recombinant cells and on membranes expressing mGlu 7 (EC 50 = 64-290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μ M. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats.
AMN082 DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
AMN082 DIHYDROCHLORIDE Suppliers
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 4401179829988
- Fax
- 4402030 700 369
- customerservice@ascentscientific.co.uk
- Country
- United Kingdom
- ProdList
- 279
- Advantage
- 60
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57423
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- 15869524721
- 3525679403@qq.com
- Country
- China
- ProdList
- 4012
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 15865264761
- 486064515@qq.com
- Country
- China
- ProdList
- 4542
- Advantage
- 58
- Tel
- 13774214275
- zhouzz@univ-bio.com
- Country
- China
- ProdList
- 24995
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24644
- Advantage
- 58