(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid

Product Name: (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid
CAS No.: 48172-10-7
Chemical Name: (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid
Synonyms: 4-PHTHALIMIDO-2-HYDROXY BUTYRIC ACID;(S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid;(S)-(+)-α-Hydroxy-1;2H-Isoindole-2-butanoicacid;Phthalimido-hydroxybutyricacid;3-dioxo-2-isoindolinebutyric acid;2-HYDROXY-4-PHTHALIMIDOBUTYRIC ACID;2-Hydroxy-4-phthalimidobutanoicacid;S-4-Phthalimido -2- hydroxybutyric acid;Phthalic acid imido hydroxybutyric acid
CBNumber: CB6853666
Molecular Formula: C12H11NO5
Formula Weight: 249.22
MOL File: 48172-10-7.mol

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(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid Property

Melting point:: 157-159 °C(lit.)
Boiling point:: 392.32°C (rough estimate)
Density: 1.3189 (rough estimate)
refractive index: 6 ° (C=1, MeOH)
storage temp.: Sealed in dry,Room Temperature
solubility: almost transparency in Methanol
form: powder to crystal
pka: 3.67±0.10(Predicted)
color: White to Almost white
optical activity: [α]20/D +6.5°, c =1 in ethanol
InChI: 1S/C12H11NO5/c14-9(12(17)18)5-6-13-10(15)7-3-1-2-4-8(7)11(13)16/h1-4,9,14H,5-6H2,(H,17,18)/t9-/m0/s1
InChIKey: YWDXODQRCDEZLN-VIFPVBQESA-N
SMILES: O[C@@H](CCN1C(=O)c2ccccc2C1=O)C(O)=O
CAS DataBase Reference: 48172-10-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 29335995
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: H0933
Product name: (S)-(+)-2-Hydroxy-4-phthalimidobutyric Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $90
Updated: 2025/07/31

TRC

Product number: H999995
Product name: (S)-(+)-2-Hydroxy-4-phthalimidobutyric Acid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0017268
Product name: 1,3-DIHYDRO-ALPHA-HYDROXY-1,3-DIOXO-2H-ISOINDOLE-2-BUTANOIC ACID
Purity: 95.00%
Packaging: 5G
Price: $909.32
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-S12
Product name: (S)-(+)-alpha-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid
Packaging: 1g
Price: $152
Updated: 2021/12/16

AK Scientific

Product number: A122
Product name: (S)-(+)-2-Hydroxy-4-phthalimidobutyric Acid
Packaging: 5g
Price: $176
Updated: 2021/12/16

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(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(+)-2-Hydroxy-4-phthalimidobutyric Acid is used in preparation method of plazomicin key intermediate for simplifying operation and improving yield.

(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid Suppliers

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J & K SCIENTIFIC LTD.

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Energy Chemical

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China Langchem Inc.

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View Lastest Price from (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid 48172-10-7
Price: US $0.00-0.00/KG
Min. Order: 25KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2025-12-29

Henan Aochuang Chemical Co.,Ltd.

Product: (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid 48172-10-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-19

Hangzhou ICH Biofarm Co., Ltd

Product: (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid 48172-10-7
Price: US $0.00-0.00/g
Min. Order: 0.1g
Purity: 98.0%(T)
Supply Ability: 100kg
Release date: 2023-07-04

48172-10-7, (2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acidRelated Search:

Phthaloyl-L- alanyl-L-glutamine PHT-LEU-OH CHLOROPHOSPHONAZO III 4-Dimethylaminobenzaldehyde DL-2-Aminobutyric acid Dimethyl 2,2'-azobis(2-methylpropionate) DL-3-Aminobutyric acid 4-Aminobutyric acid 4-Dimethylaminopyridine L(+)-2-Aminobutyric acid DL-4-Amino-3-hydroxybutyric acid 2-Hydroxy-4-amino butanoic acid r-Amino Butryric Acid N-(3-HYDROXYPROPYL)PHTHALIMIDE Butyric Acid 1,3-DIHYDRO-ALPHA-HYDROXY-1,3-DIOXO-2H-ISOINDOLE-2-BUTANOIC ACID 4-(1,3-DIHYDRO-ISOINDOL-2-YL)-BUTYRIC ACID 4-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)BUTANOIC ACID

(S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid

(S)-(+)-alpha-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid 98%

(<i>S</i>)-(+)-2-Hydroxy-4-phthalimidobutyric Acid

(2S)-4-(1,3-dioxoisoindol-2-yl)-2-hydroxybutanoic acid

4-(1,3-dioxo-2-isoindolyl)-2-hydroxybutanoate

1,3-DIHYDRO-ALPHA-HYDROXY-1,3-DIOXO-2H-ISOINDOLE-2-BUTANOIC ACID

(2S)-4-(1,3-DIOXOISOINDOLIN-2-YL)-2-HYDROXYBUTANOIC ACID

2-HYDROXY-4-PHTHALIMIDOBUTYRIC ACID

(S)-(+)-ALPHA-HYDROXY-1,3-DIOXO-2-ISOINDOLINEBUTYRIC ACID

(S)-(+)-2-HYDROXY-4-PHTHALIMIDOBUTYRIC ACID

4-PHTHALIMIDO-2-HYDROXY BUTYRIC ACID

S-4-Phthalimido -2- hydroxybutyric acid

(S)-(+)-A-HYDROXY-1,3-DIOXO-2-ISOINDOLINEBUTYRIC ACID

(S)-(+)-α-Hydroxy-1

3-dioxo-2-isoindolinebutyric acid

2-Hydroxy-4-phthalimidobutanoicacid

(s)-(+)-α-hydroxy-1,3-dioxo-2-isoindolinebutyric acid

(2S)-4-(1,3-DIOXOISOINDOLIN-2-YL)-2-HYDROXYBUTANOIC ACID 96%

L-(-)-A-HYDROXY-G-PHTHALIMIDOBUTYRIC ACID

L-(-)-A-HYDROXY-G-PHTHALIMIDOBUTYRIC ACIDAMIKACIN

(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic acid,96%

2H-Isoindole-2-butanoicacid

2H-Isoindole-2-butanoic acid, 1,3-dihydro-α-hydroxy-1,3-dioxo-, (αS)-

Phthalic acid imido hydroxybutyric acid

(2S)-4-(1,3-dioxoisoindol-2-yl)-2-hydroxybutanoicaci

(2S)-4-(1,3-Dioxoisoindolin-2-yl)-2-hydroxybutanoic

(<i>S</i>)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid

2-(1,3-Dioxoisoindolin-2-yl)-4-hydroxybutanoicacid

Phthalimido-hydroxybutyricacid

(S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid, CAS 48172-10-7

(S)-(+)-α-Hydroxy-1,3-dioxo-2-isoindolinebutyric acid

48172-10-7

C12H10NO5

C12H11NO5

Heterocyclic Building Blocks

Indoles

Chiral Building Blocks

Asymmetric Synthesis

N-Substituted Maleimides, Succinimides & Phthalimides

N-Substituted Phthalimides

N-Substituted Maleimides, Succinimides & Phthalimides

N-Substituted Phthalimides

Chiral Building Blocks

Heterocyclic Building Blocks

Indoles

chiral

API intermediates