ChemicalBook > CAS DataBase List > 8-Aminoquinoline

8-Aminoquinoline

Product Name: 8-Aminoquinoline
CAS No.: 578-66-5
Chemical Name: 8-Aminoquinoline
Synonyms: QUINOLIN-8-AMINE;8-QUINOLINAMINE;Quinolin-8-ylaMine;nc066;wr6920;AS-232;8-Amino;AKOS 91147;AKOS AUF01700;8-AminoquinoL
CBNumber: CB6853868
Molecular Formula: C9H8N2
Formula Weight: 144.17
MOL File: 578-66-5.mol

Less

8-Aminoquinoline Property

Melting point:: 60-65 °C (lit.)
Boiling point:: 174 °C/26 mmHg (lit.)
Density: 1.1148 (estimate)
refractive index: 1.7080 (estimate)
Flash point:: 174°C/26mm
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: pK1: 3.99(+1) (20°C,μ=0.01)
form: Crystalline Powder
color: Green to beige-brown
Water Solubility: slightly soluble
Sensitive: Air Sensitive
BRN: 114474
CAS DataBase Reference: 578-66-5(CAS DataBase Reference)
NIST Chemistry Reference: 8-Quinolinamine(578-66-5)
EPA Substance Registry System: 8-Quinolinamine (578-66-5)

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 68-36/37/38-20/21/22-36/38
Safety Statements: 36/37/39-26-22-36
RIDADR: UN2811
WGK Germany: 3
RTECS: VA9627000
Hazard Note: Harmful/Irritant/Air Sensitive
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29334990
Toxicity: mmo-sat 50 mg/plate MUREAV 39,285,77

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 260789
Product name: 8-Aminoquinoline
Purity: 98%
Packaging: 5g
Price: $67.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: 260789
Product name: 8-Aminoquinoline
Purity: 98%
Packaging: 25g
Price: $155.4
Updated: 2025/07/31

TCI Chemical

Product number: A0419
Product name: 8-Aminoquinoline
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $59
Updated: 2025/07/31

TCI Chemical

Product number: A0419
Product name: 8-Aminoquinoline
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $188
Updated: 2025/07/31

TCI Chemical

Product number: A0419
Product name: 8-Aminoquinoline
Purity: >98.0%(GC)(T)
Packaging: 100g
Price: $279
Updated: 2025/07/31

Less

8-Aminoquinoline Chemical Properties,Usage,Production

Chemical Properties

green to beige-brown crystalline powder

Uses

8-Aminoquinoline is used as pesticide and pharmaceutical intermediate. It has been used in the preparation of base-stabilized terminal borylene complex of osmium. It is also used in the spectrophotometric determination of bivalent palladium.

Preparation

Synthesis of 8-aminoquinoline: Under an ice bath, sulfuric acid (2.0 mL) was added onto quinoline (5 mmol, 1.0 equiv) then 65% nitric acid (3.0 equiv) were added dropwise and stirred for 4h at rt. The mixture was poured into the ice water and neutralized with NaOH; and then extracted with dichloromethane. After dried over Na2SO4 and evaporated in vacuo, used next step without purification.
Mixture of nitroquinolines and 5% Pd/C was solved in ethanol and suspension was saturated with hydrogen gas under atmospheric pressure at 40°C until the starting material was consumed. 2 h later, the mixture was filtered and evaporated. The crude product was purified by silica gel column chromatography, eluting with EtOAc in hexanes to yield the desired 8-aminoquinoline is isolated as a brown solid in a yield of 32%.
Obtained as a brown solid (231 mg, 32%); 1H NMR (500 MHz, CDCl3) δ 8.71 – 8.60 (m, 1H), 7.93 (d, J = 8.2 Hz, 1H), 7.29 – 7.16 (m, 2H), 7.02 (d, J = 8.1 Hz, 1H), 6.80 (d, J = 7.4 Hz, 1H), 4.89 (s, 2H).

General Description

8-Aminoquinoline fluoresce moderately to weakly in low dielectric media but not in strongly hydrogen-bonding or acidic aqueous media. The reaction of 8-aminoquinoline with chromium (III), manganese (II), iron (II) and (III), cobalt (II), nickel (II), copper (II), zinc (II), cadmium (II) and platinum (II) salts has been studied.

reaction suitability

reaction type: C-H Activation
reagent type: catalyst

Safety Profile

Human mutation data reported.When heated to decomposition it emits toxic fumes ofNOx.

Purification Methods

8-Aminoquinoline crystallises from EtOH, ligroin, octane or H2O, and complexes with metals. [Beilstein 22 III/IV 4708, 22/10 V 316.]

8-Aminoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

8-Quinolineboronic acid o-Phenanthroline

Less

8-Aminoquinoline Suppliers

Americas 1 Austria 1 Belgium 5 China 284 Europe 4 France 1 Germany 7 India 25 Japan 6 Slovakia 1 Switzerland 3 Ukraine 3 United Kingdom 21 United States 53 Global 415

Zhejiang Huangyan Wanfeng Pharm&Chem Co., Ltd.

Tel: 0576-84160728-688 13906593800
Email: zhangwf@wanfengchem.com
Country: China
ProdList: 49
Advantage: 58

CHANGZHOU MALONG CHEMICALS CO., LTD.

Tel: 18651958646
Email: info@malongchem.com
Country: China
ProdList: 180
Advantage: 58

Zaozhuang Benefit Chemical Co., Ltd.

Tel: 0531-69958783 15508681609
Fax: 0531-69958783
Email: 1948129184@qq.com
Country: China
ProdList: 205
Advantage: 60

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527621225
Email: 1791901229@qq.com
Country: China
ProdList: 6945
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

RYSS TECH LTD

Tel: 400-188-0725 +86 21 34310725 13611771617
Fax: +86 21 34311076
Country: China
ProdList: 2002
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3199
Advantage: 55

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5645
Advantage: 65

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Chengdu Forest Science and Technology Development Co., Ltd.

Tel: 18030648795
Fax: 028-61777050
Email: sales@cdforestchem.com
Country: China
ProdList: 2000
Advantage: 58

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

Changzhou Fourman Chemical Co., Ltd.

Tel: 0519-89882557 13912311481
Fax: 0519-8988-2559
Email: fourmanchem@163.com
Country: China
ProdList: 63
Advantage: 60

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Quzhou HuntBio Co., Ltd.

Tel: 0571-64067827 13372408495
Fax: 0571-64067827
Email: sales@huntchem.com
Country: China
ProdList: 150
Advantage: 60

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Beijin Yangguang Furui Chemical co.,Ltd.

Tel: 010-57495520 13521095525
Email: zhw512@foxmail.com
Country: China
ProdList: 488
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ShangHai D&B Biological Science and Technology Co.Ltd

Tel: 400-008-9730,021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3057
Advantage: 60

Zhengzhou ALFA Chemical Co., Ltd.

Tel: 0371-53732842 15981811963
Fax: 0371-86239377
Email: 1758257485@qq.com
Country: China
ProdList: 950
Advantage: 56

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-0371-13526885213 15637198702
Fax: 0371-63709726
Email: hsyykjchem@163.com
Country: China
ProdList: 3853
Advantage: 58

Mei Lan Industrial (Shanghai) Co., Ltd.

Tel: 021-58958189
Fax: 021-58957967
Email: wouchina@126.com
Country: China
ProdList: 2666
Advantage: 55

Less

View Lastest Price from 8-Aminoquinoline manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 8-Aminoquinoline 578-66-5
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-04

Henan Aochuang Chemical Co.,Ltd.

Product: 8-Aminoquinoline 578-66-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Henan Fengda Chemical Co., Ltd

Product: 8-Aminoquinoline 578-66-5
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-22

578-66-5, 8-AminoquinolineRelated Search:

QUINOLINE SULPHATE 8-Hydroxyquinoline Ethoxyquin Isoquinoline Quinhydrone 6-Hydroxy-2(1H)-3,4-dihydroquinolinone Quinclorac 5-Aminoquinoline 4-(Trifluoromethyl)quinolin-2-amine 6-AMINOQUINOLINE-4-CARBOXYLIC ACID 2-Aminoquinoline 2-AMINO-4-METHYL-QUINOLINE-3-CARBONITRILE 4-Aminomethylquinoline hydrochloride 3-Aminoquinoline 6-Aminoquinoline 4-Aminoguinoline 2,6-Dichloroquinolin-5-amine 5-BROMO-QUINOLIN-8-YLAMINE HYDROCHLORIDE

8-amino-quinolin

nc066

Quinoline, 8-amino-

wr6920

TIMTEC-BB SBB004126

QUINOLIN-8-AMINE

ASISCHEM Z74664

AKOS AUF01700

AKOS 91147

8-AMINOQUINOLINE

8-Aminoquinoline,98%

8-Amino

8-QUINOLINAMINE

8-QUINOLYLAMINE

8-Quinolinylamine

8-Aminoquinoline ,99%

8-AMinoquinoline, 98+% 10GR

8-AMinoquinoline, 98+% 5GR

Quinolin-8-ylaMine

Quinolin-8-amine, 8-Amino-1-azanaphthalene

AS-232

8-Aminoquinoline≥ 98% (GC)

8-AminoquinoL

8-Aminoquinoline &gt

8-Aminoquinoline ISO 9001：2015 REACH

8-Chinolylamin

TIANFU CHEM -- 8-Aminoquinoline

8-Aminoquinoline,8-Bromoquinoline

Compound 578-66-5

2,2'-Biquinoline-4,4'-diyl bis(selenide)

578-66-5

Building Blocks

Heterocyclic Building Blocks

Quinolines

Aminoquinolines

Quinolines, Quinazolines and derivatives

Quinoline&Isoquinoline

Quinolines

Aminoquinolines

quinoline