GPX4 Inhibitor Screening Assay Kit
- Product Name
- GPX4 Inhibitor Screening Assay Kit
- Chemical Name
- GPX4 Inhibitor Screening Assay Kit
- Synonyms
- GPX4 Inhibitor Screening Assay Kit
- CBNumber
- CB68571681
- Formula Weight
- 0
- MOL File
- Mol file
GPX4 Inhibitor Screening Assay Kit Chemical Properties,Usage,Production
Description
Cayman's GPX4 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human GPX4, a negative regulator of the ferroptosis pathway. The assay measures GPX4 indirectly by a coupled reaction with glutathione reductase (GR). Oxidized glutathione (GSSG), produced upon reduction of hydroperoxide by GPX4, is recycled to its reduced state by GR and NADPH. The oxidation of NADPH to NADP+ is accompanied by a decrease in absorbance at 340 nm. The rate of decrease in A340 is directly proportional to GPX4 activity. The GPX4 inhibitor ML-162 is included as a positive control.Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.WARNING This product is not for human or veterinary use.
GPX4 Inhibitor Screening Assay Kit Preparation Products And Raw materials
Raw materials
Preparation Products
GPX4 Inhibitor Screening Assay Kit Suppliers
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