(S)-2-Phenylpyrrolidine
- Product Name
- (S)-2-Phenylpyrrolidine
- CAS No.
- 59347-91-0
- Chemical Name
- (S)-2-Phenylpyrrolidine
- Synonyms
- (S)-2-Phenylpyrrolidine;(2S)-2-Phenylpyrrolidine;(2S)-2α-Phenylpyrrolidine;(S)-2-PHENYLPYRROLIDINE HCl;Pyrrolidine, 2-phenyl-, (2S)-
- CBNumber
- CB6875464
- Molecular Formula
- C10H13N
- Formula Weight
- 147.22
- MOL File
- 59347-91-0.mol
(S)-2-Phenylpyrrolidine Property
- Boiling point:
- 237.0±19.0 °C(Predicted)
- Density
- 0.988±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 10.13±0.10(Predicted)
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P998490
- Product name
- (S)-2-Phenylpyrrolidine
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- OR932248
- Product name
- (S)-2-Phenylpyrrolidine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- AS7522-A
- Product name
- (S)-2-Phenylpyrrolidine
- Purity
- 97+% ee
- Packaging
- 250mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- OR932248
- Product name
- (S)-2-Phenylpyrrolidine
- Purity
- 95%
- Packaging
- 1g
- Price
- $495
- Updated
- 2021/12/16
- Product number
- AS7522-A
- Product name
- (S)-2-Phenylpyrrolidine
- Purity
- 97+% ee
- Packaging
- 1g
- Price
- $592
- Updated
- 2021/12/16
(S)-2-Phenylpyrrolidine Chemical Properties,Usage,Production
Description
(S)-2-Phenylpyrrolidine is an amine that has been synthesized for use in research. It is chiral and can exist as either the levorotatory or dextrorotatory form. It interacts with the tropomyosin receptor, which is a protein found on the surface of muscle cells. This interaction prevents calcium ions from binding to tropomyosin, thereby preventing muscle contraction.
Uses
(S)-2-Phenylpyrrolidine has been shown to be effective in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Research also suggests that this drug may be effective at preventing aldehyde toxicity mediated by the enzyme acetaldehyde dehydrogenase 2 (ALDH2).
Reactions
(S)-2-Phenylpyrrolidine could be react with N-{3-nitro-4-[(oxan-4-ylmethyl)amino]benzenesulfonyl}-4-{2-oxo-7-azaspiro[3.5]nonan-7- y l}-2-[( 11 R, 15S)-4-{[2-(trimethy Isi ly l)ethoxy]methy I}- 13, 16-dioxa-2,4, 10- triazatetracyclo[7.7.0.0A{3,7}.0A{11,15}]hexadeca-1(9),2,5,7-tetraen-10-yl]benzamide to synthsize a intermediate of BCL-2 inhibitor. It can also be use in the preparation of the Inhibitors of ubiquitin specific protease 19 (USP19) through amine group coupling.
Synthesis
Into a 100 mL round-bottom flask were added tert-butyl (2S)- 2-phenylpyrrolidine-1-carboxylate (70 mg, 0.3 mmol, 1.0 eq) and CHsCh .0 mL), TFA (0.5 mL) at 25°C. The resulting mixture was stirred for 3 hours at 25°C. The resulting mixture was concentrated under reduced pressure. This resulted in (S)-2-Phenylpyrrolidine (40 mg, 96.0%) as colorless oil.
(S)-2-Phenylpyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-2-Phenylpyrrolidine manufacturers
- Product
- (2S)-2-phenylpyrrolidine 59347-91-0
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-08-07