2,2'-dichlorobenzidine

Product Name
2,2'-dichlorobenzidine
CAS No.
84-68-4
Chemical Name
2,2'-dichlorobenzidine
Synonyms
2,2'-dichlorobenzidine;Gentamycin Sulfate Impurity 25;2,2'-Dichlorobiphenyl-4,4'-diamine;2,2'-Dichloro-4,4'-diaminobiphenyl;4,4’-Diamino-2,2’-dichlorobiphenyl;4,4'-Diamino-2,2'-dichlorobiphenyl;4-(4-amino-2-chlorophenyl)-3-chloroaniline;[1,1'-Biphenyl]-4,4'-diamine,2,2'-dichloro-;4-(4-azanyl-2-chloro-phenyl)-3-chloro-aniline;4-(4-amino-2-chlorophenyl)-3-chlorobenzenamine
CBNumber
CB6875747
Molecular Formula
C12H10Cl2N2
Formula Weight
253.13
MOL File
84-68-4.mol
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2,2'-dichlorobenzidine Property

Melting point:
165°C
Boiling point:
398.89°C (rough estimate)
Density 
1.3171 (rough estimate)
refractive index 
1.6400 (estimate)
pka
3.58±0.10(Predicted)
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Safety

HazardClass 
IRRITANT
HS Code 
2921599090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D492648
Product name
4,4''-Diamino-2,2''-dichlorobiphenyl
Packaging
500mg
Price
$105
Updated
2021/12/16
TRC
Product number
D492648
Product name
4,4''-Diamino-2,2''-dichlorobiphenyl
Packaging
1g
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD116602
Product name
2,2'-Dichloro-1,1'-biphenyl-4,4'-diamine
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD116602
Product name
2,2'-Dichloro-1,1'-biphenyl-4,4'-diamine
Packaging
500mg
Price
$100
Updated
2021/12/16
AK Scientific
Product number
0495AF
Product name
2,2'-Dichloro-1,1'-biphenyl-4,4'-diamine
Packaging
250mg
Price
$136
Updated
2021/12/16
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2,2'-dichlorobenzidine Chemical Properties,Usage,Production

Chemical Properties

3,3' -Dichlorobenzidine is barely discolored on exposure to air and is chemically resistant to water. Oxidizing agents, such as bromine water, potassium dichromate, and iron(III) chloride, cause the formation of a green color. With gold, the green color is still detectable at a dilution of 1 : 5000000. N-Acetyl-3,3' -dichlorobenzidine and N,N' - diacetyl-3,3' -dichlorobenzidine form when 3,3' - dichlorobenzidine is treated with acetic anhydride in dilute alcohol. The tetrazotizing behavior is similar to that of benzidine and o-tolidine.

Uses

4,4''-Diamino-2,2''-Dichlorobiphenyl is a useful reactant for the synthesis of benzidine, L-?proline, and diaminofluorene derivatives which are hepatitis C virus NS5A inhibitors.

Uses

3,3' -Dichlorobenzidine was introduced about 1932 and is now the most important diphenyl base. It is used as the starting material for pigments with yellow and red shades. These are used for coloring printing inks, paints, plastics, and rubbers. The important diarylide yellow pigments, which are incorrectly known as benzidine yellows, are formed by the combination of 3,3' - dichlorobenzidine with acetic acid arylides. 3,3' - Dichlorobenzidine is also used in the production of polyurethane rubbers.

Production Methods

3,3' -Dichlorobenzidine is made from o-nitro-chlorobenzene by reduction with zinc dust and sodium hydroxide solution and subsequent rearrangement with dilute hydrochloric acid or sulfuric acid. It is assayed by titration with sodium nitrite solution in dilute hydrochloric acid and detected in human urine by colorimetry using chloramine. The detection limit is 0.1 mg/kg.

Production Methods

2,2' -Dichlorobenzidine is made from m-nitrochlorobenzene, preferably using zinc dust and sodium hydroxide solution. It is subsequently rearranged and isolated in the form of a dihydrochloride.

Solubility in water

It is almost insoluble in water but readily soluble in alcohol.

Purification Methods

Crystallise the benzidine from EtOH or H2O. [Beilstein 13 H 234, 13 I 66, 13 II 106, 13 III 477, 13 IV 384.]

2,2'-dichlorobenzidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2'-dichlorobenzidine Suppliers

China 22 France 1 India 1 United Kingdom 1 United States 4 Global 29
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Amadis Chemical Company Limited
Tel
571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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Aikon International Limited
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025-58859352 18068836627
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(5)02557626880
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dt3@aikonchem.com
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China
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15493
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Henan Alfachem Co.,Ltd.
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0371-55051623 18137891487
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QQ：2853979817
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2853979817@qq.com
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China
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Shanghai Jizhi Biochemical Technology Co. Ltd.
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4009004166/18616739031 18616739031
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3007523370@qq.com
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China
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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China
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Shanghai Thunder Biological Technology Co., Ltd.
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18621609968
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1162686636@qq.com
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China
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876
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Nanjing Hengbei Chemicals Co., Ltd.
Tel
+86-25-58393656
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+86-25-58393656
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sales@hengbeichem.cn
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China
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6854
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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sales@accelachem.com
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China
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10467
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QUALITY CONTROL SOLUTIONS LTD.
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+86-0755-66853366 +86-13670046396
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export03@qcsrm.com
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Shanghai Maclean Biochemical Technology Co., LTD
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021-021-50706066 15221275939
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shenlinxing@macklin.cn
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China
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Zhuhai Aobokai Biomedical Technology Co., Ltd.
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400-0628126 18736790110;
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sales-team@aobchem.com.cn
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Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
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Biosynth Biological Technology (Suzhou) Co Ltd
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51288865780
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sales@biosynth.com
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Santa Cruz Biotechnology Inc
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021-60936350
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scbt@scbt.com
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China
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Hubei Yangxin Medical Technology Co., Ltd.
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0714-3299675 13092790750
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3003355938@qq.com
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DAYANG CHEM (HANGZHOU) CO.,LTD
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+86-88938639 +86-17705817739
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HANGZHOU LEAP CHEM CO., LTD.
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+86-571-87711850
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Absin Bioscience Inc.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Dynasty Colourants Co., Ltd.
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84-68-4, 2,2'-dichlorobenzidineRelated Search:

2,2'-DICHLOROBIPHENYL 2,2'-DICHLORO-5,5'-DIMETHOXYBENZIDINE Pigment Yellow 81 2′-Chloro[1,1′-biphenyl]-4-amine 2,2',5,5'-Tetrachlorobenzidine 2,2'-dichlorobenzidine

  • 4-(4-amino-2-chlorophenyl)-3-chlorobenzenamine
  • 2,2'-Dichloro-4,4'-diaminobiphenyl
  • 2,2'-Dichlorobiphenyl-4,4'-diamine
  • 2,2'-dichlorobenzidine
  • 4,4'-Diamino-2,2'-dichlorobiphenyl
  • [4-(4-amino-2-chloro-phenyl)-3-chloro-phenyl]amine
  • 4-(4-amino-2-chlorophenyl)-3-chloroaniline
  • 4-(4-azanyl-2-chloro-phenyl)-3-chloro-aniline
  • [1,1'-Biphenyl]-4,4'-diamine,2,2'-dichloro-
  • 4,4’-Diamino-2,2’-dichlorobiphenyl
  • Gentamycin Sulfate Impurity 25
  • 2,2′-dichloro-1,1′-biphenyl-4,4′-diamine, CAS 84-68-4
  • 84-68-4