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diisopromine

Product Name
diisopromine
CAS No.
5966-41-6
Chemical Name
diisopromine
Synonyms
R 253;Do-Bil;Megabyl;Hepacol;Hepabyl;Cholagol;DisproMine;Disopromine;diisopromine;N,N-Diisopropyl-3,3- diphenylpropylaMine
CBNumber
CB6907426
Molecular Formula
C21H29N
Formula Weight
295.46
MOL File
5966-41-6.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D446540
Product name
Diisopromine
Packaging
250mg
Price
$1230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007975
Product name
DIISOPROMINE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007975
Product name
DIISOPROMINE
Purity
95.00%
Packaging
25MG
Price
$739.2
Updated
2021/12/16
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diisopromine Chemical Properties,Usage,Production

Originator

Agofell,Janssen-Cilag

Uses

Spasmolitic; choleretic.

Definition

ChEBI: Diisopromine is a diarylmethane.

Manufacturing Process

A vigorously stirred suspension of 0.2 to 1 mole of sodium amide in 200 ml of xylene, in which 0.1 moles of 4-diisopropylamino-2,2-diphenyl-butyronitrile were dissolved, was boiled for about twelve hours. After this the excess of sodium amide was decomposed with water and the xylene layer was separated, washed with water and extracted with dilute hydrochloric acid. This acidic extract was made strongly alkaline with a concentrated aqueous sodium hydroxide solution and the separated base was extracted with ether. After drying, the ether evaporated and the 1,1-diphenyl-3-diisopropylaminopropane was distilled in vacuum. The oil obtained can be dissolved in ether and after introduction of hydrochloric acid gas the hydrochloric acid addition salt precipitates. It shows a melting point of 171°C.

Therapeutic Function

Spasmolytic, Choleretic

diisopromine Preparation Products And Raw materials

Raw materials

Preparation Products

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diisopromine Suppliers

J & K SCIENTIFIC LTD.
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Energy Chemical
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5966-41-6, diisopromineRelated Search:


  • diisopromine
  • Disopromine
  • N,N-Diisopropyl-3,3-diphenyl-1-propanamine
  • Cholagol
  • DisproMine
  • Do-Bil
  • Hepabyl
  • Hepacol
  • Megabyl
  • N,N-Bis(1-Methylethyl)-γ-phenylbenzenepropanaMine
  • N,N-Diisopropyl-3,3- diphenylpropylaMine
  • R 253
  • Benzenepropanamine, N,N-bis(1-methylethyl)-γ-phenyl-
  • 3,3-diphenyl-N,N-di(propan-2-yl)propan-1-amine
  • 5966-41-6
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals