diisopromine
- Product Name
- diisopromine
- CAS No.
- 5966-41-6
- Chemical Name
- diisopromine
- Synonyms
- R 253;Do-Bil;Megabyl;Hepacol;Hepabyl;Cholagol;DisproMine;Disopromine;diisopromine;N,N-Diisopropyl-3,3- diphenylpropylaMine
- CBNumber
- CB6907426
- Molecular Formula
- C21H29N
- Formula Weight
- 295.46
- MOL File
- 5966-41-6.mol
N-Bromosuccinimide Price
- Product number
- D446540
- Product name
- Diisopromine
- Packaging
- 250mg
- Price
- $1230
- Updated
- 2021/12/16
- Product number
- API0007975
- Product name
- DIISOPROMINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $1871.1
- Updated
- 2021/12/16
- Product number
- API0007975
- Product name
- DIISOPROMINE
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $739.2
- Updated
- 2021/12/16
diisopromine Chemical Properties,Usage,Production
Originator
Agofell,Janssen-Cilag
Uses
Spasmolitic; choleretic.
Definition
ChEBI: Diisopromine is a diarylmethane.
Manufacturing Process
A vigorously stirred suspension of 0.2 to 1 mole of sodium amide in 200 ml of xylene, in which 0.1 moles of 4-diisopropylamino-2,2-diphenyl-butyronitrile were dissolved, was boiled for about twelve hours. After this the excess of sodium amide was decomposed with water and the xylene layer was separated, washed with water and extracted with dilute hydrochloric acid. This acidic extract was made strongly alkaline with a concentrated aqueous sodium hydroxide solution and the separated base was extracted with ether. After drying, the ether evaporated and the 1,1-diphenyl-3-diisopropylaminopropane was distilled in vacuum. The oil obtained can be dissolved in ether and after introduction of hydrochloric acid gas the hydrochloric acid addition salt precipitates. It shows a melting point of 171°C.
Therapeutic Function
Spasmolytic, Choleretic