2-Hydroxy-5-Trifluoromethyl Benzoic Acid
- Product Name
- 2-Hydroxy-5-Trifluoromethyl Benzoic Acid
- CAS No.
- 79427-88-6
- Chemical Name
- 2-Hydroxy-5-Trifluoromethyl Benzoic Acid
- Synonyms
- UKRORGSYN-BB BBV-264038;5-Trifluoromethyl-2-hydroxybenzoic acid;2-Hydroxy-5-Trifluoromethyl Benzoic Acid;Benzoic acid, 2-hydroxy-5-(trifluoromethyl)-;2-Hydroxy-5-Trifluoromethyl Benzoic Acid ISO 9001：2015 REACH;2-Carboxy-4-(trifluoromethyl)phenol, 3-Carboxy-4-hydroxybenzotrifluoride, 5-(Trifluoromethyl)salicylic acid
- CBNumber
- CB6950134
- Molecular Formula
- C8H5F3O3
- Formula Weight
- 206.12
- MOL File
- 79427-88-6.mol
2-Hydroxy-5-Trifluoromethyl Benzoic Acid Property
- Boiling point:
- 292.8±40.0 °C(Predicted)
- Density
- 1.539±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 2.55±0.10(Predicted)
- form
- solid
- color
- White
- InChI
- InChI=1S/C8H5F3O3/c9-8(10,11)4-1-2-6(12)5(3-4)7(13)14/h1-3,12H,(H,13,14)
- InChIKey
- YQDOJQUHDQGQPH-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(C(F)(F)F)=CC=C1O
Safety
- HS Code
- 2918290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- H977535
- Product name
- 2-Hydroxy-5-(trifluoromethyl)benzoicacid
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- H977535
- Product name
- 2-Hydroxy-5-(trifluoromethyl)benzoicacid
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- PC5736
- Product name
- 2-Hydroxy-5-(trifluoromethyl)benzoicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- PC5736
- Product name
- 2-Hydroxy-5-(trifluoromethyl)benzoicacid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $66
- Updated
- 2021/12/16
- Product number
- 2829-3-Y0
- Product name
- 2-Hydroxy-5-(trifluoromethyl)benzoic acid
- Packaging
- 250mg
- Price
- $92
- Updated
- 2021/12/16
2-Hydroxy-5-Trifluoromethyl Benzoic Acid Chemical Properties,Usage,Production
Uses
2-Hydroxy-5-(trifluoromethyl)benzoic acid
Synthesis
454-92-2
79427-88-6
General procedure for the synthesis of 2-hydroxy-5-trifluoromethylbenzoic acid from 3-trifluoromethylbenzoic acid: III. General method for Pd(II)-catalyzed tert-butyl-hydroxylation reaction 02: To a 50 mL high-pressure reactor equipped with a magnetic stir bar was added Pd(OAc)2 (11.2 mg, 0.05 mmol) followed by 3-trifluoromethylbenzoic acid (0.5 mmol), benzoquinone (54.0 mg, 0.5 mmol), KOAc (98.0 mg, 1 mmol), and N,N-dimethylacetamide (1.5 mL). The reaction vessel was filled with O2 (20 atm), then evacuated and filled again with O2 (5 atm, repeated twice). The reaction mixture was stirred at 115 °C for 15 h and then cooled to room temperature. After completion of the reaction, the crude product was purified according to the previous post-treatment of hydroxylation reaction under 1 atm O2 conditions.
References
[1] Journal of the American Chemical Society, 2009, vol. 131, # 41, p. 14654 - 14655
[2] Patent: WO2011/37929, 2011, A2. Location in patent: Page/Page column 14; 19-20
[3] Synlett, 2016, vol. 27, # 2, p. 277 - 281
2-Hydroxy-5-Trifluoromethyl Benzoic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Hydroxy-5-Trifluoromethyl Benzoic Acid manufacturers
- Product
- 2-Hydroxy-5-Trifluoromethyl Benzoic Acid 79427-88-6
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-10