ChemicalBook > CAS DataBase List > 2-Hydroxy-5-Trifluoromethyl Benzoic Acid

2-Hydroxy-5-Trifluoromethyl Benzoic Acid

Product Name
2-Hydroxy-5-Trifluoromethyl Benzoic Acid
CAS No.
79427-88-6
Chemical Name
2-Hydroxy-5-Trifluoromethyl Benzoic Acid
Synonyms
UKRORGSYN-BB BBV-264038;5-Trifluoromethyl-2-hydroxybenzoic acid;2-Hydroxy-5-Trifluoromethyl Benzoic Acid;Benzoic acid, 2-hydroxy-5-(trifluoromethyl)-;2-Hydroxy-5-Trifluoromethyl Benzoic Acid ISO 9001：2015 REACH;2-Carboxy-4-(trifluoromethyl)phenol, 3-Carboxy-4-hydroxybenzotrifluoride, 5-(Trifluoromethyl)salicylic acid
CBNumber
CB6950134
Molecular Formula
C8H5F3O3
Formula Weight
206.12
MOL File
79427-88-6.mol
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2-Hydroxy-5-Trifluoromethyl Benzoic Acid Property

Boiling point:
292.8±40.0 °C(Predicted)
Density 
1.539±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
2.55±0.10(Predicted)
form 
solid
color 
White
InChI
InChI=1S/C8H5F3O3/c9-8(10,11)4-1-2-6(12)5(3-4)7(13)14/h1-3,12H,(H,13,14)
InChIKey
YQDOJQUHDQGQPH-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(C(F)(F)F)=CC=C1O
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Safety

HS Code 
2918290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
H977535
Product name
2-Hydroxy-5-(trifluoromethyl)benzoicacid
Packaging
100mg
Price
$65
Updated
2021/12/16
TRC
Product number
H977535
Product name
2-Hydroxy-5-(trifluoromethyl)benzoicacid
Packaging
50mg
Price
$55
Updated
2021/12/16
Apolloscientific
Product number
PC5736
Product name
2-Hydroxy-5-(trifluoromethyl)benzoicacid
Purity
98%
Packaging
1g
Price
$160
Updated
2021/12/16
Apolloscientific
Product number
PC5736
Product name
2-Hydroxy-5-(trifluoromethyl)benzoicacid
Purity
98%
Packaging
250mg
Price
$66
Updated
2021/12/16
SynQuest Laboratories
Product number
2829-3-Y0
Product name
2-Hydroxy-5-(trifluoromethyl)benzoic acid
Packaging
250mg
Price
$92
Updated
2021/12/16
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2-Hydroxy-5-Trifluoromethyl Benzoic Acid Chemical Properties,Usage,Production

Uses

2-Hydroxy-5-(trifluoromethyl)benzoic acid

Synthesis

454-92-2

79427-88-6

General procedure for the synthesis of 2-hydroxy-5-trifluoromethylbenzoic acid from 3-trifluoromethylbenzoic acid: III. General method for Pd(II)-catalyzed tert-butyl-hydroxylation reaction 02: To a 50 mL high-pressure reactor equipped with a magnetic stir bar was added Pd(OAc)2 (11.2 mg, 0.05 mmol) followed by 3-trifluoromethylbenzoic acid (0.5 mmol), benzoquinone (54.0 mg, 0.5 mmol), KOAc (98.0 mg, 1 mmol), and N,N-dimethylacetamide (1.5 mL). The reaction vessel was filled with O2 (20 atm), then evacuated and filled again with O2 (5 atm, repeated twice). The reaction mixture was stirred at 115 °C for 15 h and then cooled to room temperature. After completion of the reaction, the crude product was purified according to the previous post-treatment of hydroxylation reaction under 1 atm O2 conditions.

References

[1] Journal of the American Chemical Society, 2009, vol. 131, # 41, p. 14654 - 14655
[2] Patent: WO2011/37929, 2011, A2. Location in patent: Page/Page column 14; 19-20
[3] Synlett, 2016, vol. 27, # 2, p. 277 - 281

2-Hydroxy-5-Trifluoromethyl Benzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Hydroxy-5-Trifluoromethyl Benzoic Acid manufacturers

Career Henan Chemical Co
Product
2-Hydroxy-5-Trifluoromethyl Benzoic Acid 79427-88-6
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-10

79427-88-6, 2-Hydroxy-5-Trifluoromethyl Benzoic AcidRelated Search:

3-cyano-2-methoxybenzoic acid Benzoic acid, 3-chloro-2-(trifluoromethyl)- 3,5-Dichloro-4-Methylbenzoyl chloride 2-Cyano-3-fluorobenzoic acid Benzoic acid, 3-broMo-2,6-diMethyl- 2-Chloro-6-(trifluoromethyl)be 3-FLUORO-2-HYDROXYBENZOIC ACID 4-Hydrazinylbenzoic acid Methyl salicylate Dihydroxybenzoic acid 4-Hydroxybenzoic acid 2-Hydroxy-5-Trifluoromethyl Benzoic Acid 2-Methoxy-5-(trifluoromethyl)benzoic acid RARECHEM AL BI 1430 RARECHEM AL BI 1427 RARECHEM AL BF 1427 BUTTPARK 87\03-66 RARECHEM AL BE 1427

  • 2-Hydroxy-5-Trifluoromethyl Benzoic Acid
  • UKRORGSYN-BB BBV-264038
  • 2-Carboxy-4-(trifluoromethyl)phenol, 3-Carboxy-4-hydroxybenzotrifluoride, 5-(Trifluoromethyl)salicylic acid
  • 5-Trifluoromethyl-2-hydroxybenzoic acid
  • Benzoic acid, 2-hydroxy-5-(trifluoromethyl)-
  • 2-Hydroxy-5-Trifluoromethyl Benzoic Acid ISO 9001：2015 REACH
  • 79427-88-6