2-FLUORO-6-IODOBENZALDEHYDE
- Product Name
- 2-FLUORO-6-IODOBENZALDEHYDE
- CAS No.
- 146137-72-6
- Chemical Name
- 2-FLUORO-6-IODOBENZALDEHYDE
- Synonyms
- 2-Fluoro-6-iodobenzaldehyde97%;Benzaldehyde, 2-fluoro-6-iodo-;1-Fluoro-2-formyl-3-iodobenzene;146137-72-6;2-
Fluoro- 6- iodobenzaldehyde - CBNumber
- CB6972381
- Molecular Formula
- C7H4FIO
- Formula Weight
- 250.01
- MOL File
- 146137-72-6.mol
2-FLUORO-6-IODOBENZALDEHYDE Property
- Melting point:
- 36-40 °C
- Boiling point:
- 257.7±25.0 °C(Predicted)
- Density
- 1.962±0.06 g/cm3(Predicted)
- Flash point:
- 110 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- fused solid
- color
- Bright yellow liquid
N-Bromosuccinimide Price
- Product number
- 682489
- Product name
- 2-Fluoro-6-iodobenzaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $30
- Updated
- 2025/07/31
- Product number
- 2615-K-26
- Product name
- 2-Fluoro-6-iodobenzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- 043104
- Product name
- 2-Fluoro-6-iodobenzaldehyde
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
- Product number
- 2615-K-26
- Product name
- 2-Fluoro-6-iodobenzaldehyde
- Purity
- 98%
- Packaging
- 5G
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 043104
- Product name
- 2-Fluoro-6-iodobenzaldehyde
- Packaging
- 5g
- Price
- $149
- Updated
- 2021/12/16
2-FLUORO-6-IODOBENZALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
off-white crystalline
Synthesis
1121-86-4
68-12-2
146137-72-6
Procedure: 1. To a solution of 1-fluoro-3-iodobenzene (5.00 g, 22.5 mmol) in tetrahydrofuran (THF, 50 mL) was slowly added lithium diisopropylammonium (LDA, 17.0 mL, 33.7 mmol) dropwise at -78 °C. The reaction temperature was maintained at -78 °C for 2 hours. After maintaining the reaction temperature at -78 °C and stirring for 2 h, N,N-dimethylformamide (DMF, 4.90 g, 67.5 mmol) was added and stirring was continued at -78 °C for 30 min. 2. Upon completion of the reaction, the reaction was quenched with an aqueous ammonium chloride solution (20 mL) and water (30 mL), followed by extraction with ethyl ether (3 x 30 mL). The organic layers were combined, washed sequentially with 2N hydrochloric acid (20 mL) and saturated saline (20 mL), and dried over anhydrous sodium sulfate.3. The solvent was removed by pressure-relief concentration, and the resulting crude product was purified by column chromatography on silica gel, with the eluent being petroleum ether/ethyl acetate (100:1 to 50:1), to give 6-fluoro-2-iodobenzaldehyde (3.7 g, 66% yield). The product was characterized by 1H NMR (DMSO-d6, 500 MHz): δ10.01 (s, 1H), 7.89-7.79 (m, 1H), 7.44-7.40 (m, 2H).
References
[1] Patent: WO2013/41539, 2013, A1. Location in patent: Page/Page column 55; 56
[2] Patent: US2014/206702, 2014, A1. Location in patent: Paragraph 0277
[3] Chemistry - A European Journal, 2013, vol. 19, # 27, p. 8875 - 8883
[4] Tetrahedron Letters, 1992, vol. 33, # 49, p. 7499 - 7502
[5] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 12, p. 2998 - 3001
2-FLUORO-6-IODOBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-FLUORO-6-IODOBENZALDEHYDE Suppliers
- Tel
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- Country
- Switzerland
- ProdList
- 6896
- Advantage
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View Lastest Price from 2-FLUORO-6-IODOBENZALDEHYDE manufacturers
- Product
- 2-FLUORO-6-IODOBENZALDEHYDE 146137-72-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2-FLUORO-6-IODOBENZALDEHYDE 146137-72-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 2-FLUORO-6-IODOBENZALDEHYDE 146137-72-6
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%-99%
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-07