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CIPROXIFAN

Product Name
CIPROXIFAN
CAS No.
184025-19-2
Chemical Name
CIPROXIFAN
Synonyms
CS-109;CIPROXIFAN;FUB359 Maleate;FUB-359 Maleate;FUB 359 Maleate;Ciproxifan Moleate;FUB 359 Maleate salt;Ciproxifan maleate, >=98%;Ciproxifan Maleate (FUB-359);Ciproxifan maleate(FUB-359 maleate)
CBNumber
CB6972679
Molecular Formula
C16H18N2O2.C4H4O4
Formula Weight
386.402
MOL File
184025-19-2.mol
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CIPROXIFAN Property

storage temp. 
Store at -20°C
solubility 
DMSO: soluble32mg/mL
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6848
Product name
Ciproxifan maleate
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$211
Updated
2024/03/01
Sigma-Aldrich
Product number
C6848
Product name
Ciproxifan maleate
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$732
Updated
2024/03/01
Cayman Chemical
Product number
29513
Product name
Ciproxifan (maleate)
Packaging
5mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
29513
Product name
Ciproxifan (maleate)
Packaging
25mg
Price
$435
Updated
2024/03/01
Cayman Chemical
Product number
29513
Product name
Ciproxifan (maleate)
Packaging
1mg
Price
$33
Updated
2024/03/01
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CIPROXIFAN Chemical Properties,Usage,Production

Description

Ciproxifan is a histamine H3 receptor antagonist (Ki = 0.5 nM for inhibition of histamine release in rat synaptosomal preparations). It is selective for histamine H3 over histamine H1 and H2, M3 muscarinic, and α1D- and β1-adrenergic receptors (Kis = 3.15-25 μM), as well as the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, 5-HT3, and 5-HT4 (Kis = 1.58-15 μM) in radioligand binding assays. Ciproxifan (3-300 nM) inhibits relaxation in precontracted isolated guinea pig ileal longitudinal muscle induced by R-(–)-α-methylhistamine . In vivo, ciproxifan reduces R-(–)-α-methylhistamine-induced water consumption in rats (ED50 = 0.09 mg/kg). It increases wake episode duration and latency to fall asleep in rats when administered at a dose of 2 mg/kg.

Uses

Ciproxifan is a potent histamine H3 receptor antagonist which affects histamine levels in the brain. It may be used in treatments for sleep and neurological disorders.

Biochem/physiol Actions

Potent, selective H3 histamine receptor antagonist.

CIPROXIFAN Preparation Products And Raw materials

Raw materials

Preparation Products

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CIPROXIFAN Suppliers

Canada 1 China 63 Switzerland 1 United Kingdom 1 United States 15 Global 81
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
SALES@UHNSHANGHAI.COM
Country
China
ProdList
977
Advantage
58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2784
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9798
Advantage
50
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
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View Lastest Price from CIPROXIFAN manufacturers

Career Henan Chemical Co
Product
(Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone 184025-19-2
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

184025-19-2, CIPROXIFANRelated Search:

2-Isopropylimidazole

  • Ciproxifan Moleate
  • FUB 359 Maleate
  • FUB359 Maleate
  • FUB-359 Maleate
  • Ciproxifan maleate, >=98%
  • Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt
  • (4-(3-(1H-Imidazol-5-yl)propoxy)phenyl)(cyclopropyl)methanone maleate
  • CIPROXIFAN
  • FUB 359 maleate salt, Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt
  • FUB 359 Maleate salt
  • Methanone, cyclopropyl[4-[3-(1H-iMidazol-4-yl)propoxy]phenyl]-, (Z)-2-butenedioate (1:1)
  • Cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxy]phenyl]methanone (2Z)-2-butenedioate
  • Ciproxifan Maleate (FUB-359)
  • (Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone
  • FUB 359 MALEATE;FUB359 MALEATE;FUB-359 MALEATE
  • Ciproxifan maleate(FUB-359 maleate)
  • CS-109
  • Inhibitor,aging,inhibit,Ciproxifan,disorders,Ciproxifan maleate,FUB359,Histamine Receptor,FUB-359,histamine,Alzheimer's
  • 184025-19-2
  • C16H18N2O2C4H4O4
  • Inhibitors