CIPROXIFAN
- Product Name
- CIPROXIFAN
- CAS No.
- 184025-19-2
- Chemical Name
- CIPROXIFAN
- Synonyms
- CS-109;CIPROXIFAN;FUB359 Maleate;FUB-359 Maleate;FUB 359 Maleate;Ciproxifan Moleate;FUB 359 Maleate salt;Ciproxifan maleate, >=98%;Ciproxifan Maleate (FUB-359);Ciproxifan maleate(FUB-359 maleate)
- CBNumber
- CB6972679
- Molecular Formula
- C16H18N2O2.C4H4O4
- Formula Weight
- 386.402
- MOL File
- 184025-19-2.mol
CIPROXIFAN Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble32mg/mL
- form
- powder
- color
- white to beige
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-43
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C6848
- Product name
- Ciproxifan maleate
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $211
- Updated
- 2024/03/01
- Product number
- C6848
- Product name
- Ciproxifan maleate
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $732
- Updated
- 2024/03/01
- Product number
- 29513
- Product name
- Ciproxifan (maleate)
- Packaging
- 5mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 29513
- Product name
- Ciproxifan (maleate)
- Packaging
- 25mg
- Price
- $435
- Updated
- 2024/03/01
- Product number
- 29513
- Product name
- Ciproxifan (maleate)
- Packaging
- 1mg
- Price
- $33
- Updated
- 2024/03/01
CIPROXIFAN Chemical Properties,Usage,Production
Description
Ciproxifan is a histamine H3 receptor antagonist (Ki = 0.5 nM for inhibition of histamine release in rat synaptosomal preparations). It is selective for histamine H3 over histamine H1 and H2, M3 muscarinic, and α1D- and β1-adrenergic receptors (Kis = 3.15-25 μM), as well as the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, 5-HT3, and 5-HT4 (Kis = 1.58-15 μM) in radioligand binding assays. Ciproxifan (3-300 nM) inhibits relaxation in precontracted isolated guinea pig ileal longitudinal muscle induced by R-(–)-α-methylhistamine . In vivo, ciproxifan reduces R-(–)-α-methylhistamine-induced water consumption in rats (ED50 = 0.09 mg/kg). It increases wake episode duration and latency to fall asleep in rats when administered at a dose of 2 mg/kg.
Uses
Ciproxifan is a potent histamine H3 receptor antagonist which affects histamine levels in the brain. It may be used in treatments for sleep and neurological disorders.
Biochem/physiol Actions
Potent, selective H3 histamine receptor antagonist.
CIPROXIFAN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from CIPROXIFAN manufacturers
- Product
- (Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone 184025-19-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-01