XIAP Antibody
Source Reactivity Background References- Product Name
- XIAP Antibody
- Chemical Name
- XIAP Antibody
- Synonyms
- XIAP Antibody;Mouse Monoclonal XIAP Antibody
- CBNumber
- CB6983200
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb106468
- Product name
- XIAP antibody
- Purity
- Immunogen affinity purified
- Packaging
- 20μl(Trial size)
- Price
- $256.7
- Updated
- 2021/12/16
- Product number
- orb163182
- Product name
- XIAP antibody
- Purity
- Affinity-purified by affinity-chromatography using epitope-specific immunogen.
- Packaging
- 100μg
- Price
- $280.5
- Updated
- 2021/12/16
- Product number
- orb106468
- Product name
- XIAP antibody
- Purity
- Immunogen affinity purified
- Packaging
- 50μl
- Price
- $357
- Updated
- 2021/12/16
- Product number
- orb11576
- Product name
- XIAP antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $402.9
- Updated
- 2021/12/16
- Product number
- orb106468
- Product name
- XIAP antibody
- Purity
- Immunogen affinity purified
- Packaging
- 100μL
- Price
- $406.3
- Updated
- 2021/12/16
XIAP Antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Mouse;Rat;Monkey;Human
Background
The inhibitor of apoptosis protein family consists of an evolutionarily conserved group of apoptosis inhibitors containing a conserved 70 amino acid BIR domain. Human members of this family include c-IAP1, c-IAP2, XIAP, survivin, livin, and NAIP. Overexpression of IAP family members, particularly survivin and livin, in cancer cell lines and primary tumors suggests an important role for these proteins in cancer progression. In general, the IAP proteins function through direct interactions to inhibit the activity of several caspases, including caspase-3, caspase-7, and caspase-9. In addition, binding of IAP family members to the mitochondrial protein Smac blocks their interaction with caspase-9, thereby allowing the processing and activation of the caspase.
References
[1] Deveraux, Q.L. and Reed, J.C. (1999) Genes Dev 13, 239-52.
[2] Deveraux, Q.L. et al. (1998) EMBO J 17, 2215-23.
[3] Altieri, D.C. et al. (1999) Lab Invest 79, 1327-33.
[4] Tamm, I. et al. (2000) Clin Cancer Res 6, 1796-803.
[5] Kasof, G.M. and Gomes, B.C. (2001) J Biol Chem 276, 3238-46.
[6] Deveraux, Q.L. et al. (1997) Nature 388, 300-4.
XIAP Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
XIAP Antibody Suppliers
- Tel
- 021-38015121 18438616290
- lanwu@univ-bio.com
- Country
- China
- ProdList
- 24731
- Advantage
- 58
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- 027-87196173
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- Country
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- Country
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- Country
- China
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- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
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