ChemicalBook > CAS DataBase List > H-GAMMA-ABU-OBZL P-TOSYLATE

H-GAMMA-ABU-OBZL P-TOSYLATE

Product Name
H-GAMMA-ABU-OBZL P-TOSYLATE
CAS No.
26727-22-0
Chemical Name
H-GAMMA-ABU-OBZL P-TOSYLATE
Synonyms
4-Abu-obzl.tos;H-GABA-OBzl·TosOH;H-g-Abu-OBzl·TosOH;H-γ-Abu-OBzl·TosOH;H-γ-Abu-Obzl.TosOH;H-ABU(4)-OBZL TOS-OH;Hγ-Abu-OBzl·p-tosylate;H-GAMMA-ABU-OBZL TOS-OH;H-GABA-OBzl · p-tosylate;gamma-Abu-OBzl p-tosylate
CBNumber
CB7101939
Molecular Formula
C18H23NO5S
Formula Weight
365.44
MOL File
26727-22-0.mol
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H-GAMMA-ABU-OBZL P-TOSYLATE Property

storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FA56176
Product name
gamma-Aminobutyric acid benzyl ester p-tosylate
Packaging
25g
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
093954
Product name
Benzyl 4-aminobutanoate 4-methylbenzenesulfonate
Purity
95+%
Packaging
1g
Price
$189
Updated
2021/12/16
AK Scientific
Product number
J95736
Product name
Benzyl4-aminobutanoate4-methylbenzenesulfonate
Packaging
100g
Price
$260
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA56176
Product name
gamma-Aminobutyric acid benzyl ester p-tosylate
Packaging
50g
Price
$275
Updated
2021/12/16
Chem-Impex
Product number
14954
Product name
γ-Aminobutyricacidbenzylesterp-tosylate,≥98%(HPLC)
Purity
≥98%(HPLC)
Packaging
100G
Price
$343.62
Updated
2021/12/16
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H-GAMMA-ABU-OBZL P-TOSYLATE Chemical Properties,Usage,Production

Synthesis

104-15-4

100-51-6

56-12-2

26727-22-0

A suspension of γ-aminobutyric acid (GABA) (3.50 g, 0.034 mol), benzyl alcohol (7.30 g, 7 mL, 0.068 mol), and p-toluenesulfonic acid monohydrate (PTSA) (7.10 g, 0.037 mol) was heated to reflux for 5 hr in toluene (200 mL), and the resulting water was removed by azeotropic distillation. Upon completion of the reaction, the mixture was concentrated to one-third of the original volume and the product was subsequently precipitated by the addition of ether (100 mL). The precipitate was collected by filtration, dissolved in methanol (60 mL) and reprecipitated by adding ether (100 mL) again. After filtration, it was dried to obtain 4-methylbenzenesulfonate, 4-aminobutyric acid benzyl ester (12.30 g, 99% yield) in the form of white crystals. The melting point of the product was 106.2-106.7 °C (determined in ether); Infrared spectrum (ATR): 3100, 3039, 2942, 1732, 1642, 1532, 1188, 1125 cm^-1; ^1H NMR (200 MHz, CD3OD): δ = 7.71 (d, J = 8.0 Hz, 2H, HPTSA), and 7.37-7.30 (m, 5H, HCAr), 7.20 (d, J=8.4 Hz, 2H, HPTSA), 5.11 (s, 2H, H2CBn), 2.95 (t, J=7.5 Hz, 2H, H2C(4)GABA), 2.47 (t, J=7.3 Hz, 2H, H2C(2)GABA), 2.33 (s 3H, H3CPTSA), 1.92 (quint, J=7.4 Hz, 2H, H2C(3)GABA) ppm; ^13C NMR (50 MHz, CD3OD): δ=173.83 (CO2Bn), 143.35, 141.82, 137.43, 129.91, 129.59, 129.30, 126.91 (CAr), 67.44 (CH2Bn), 40.00 (CH2(4)GABA), 31.59 (CH2(2)GABA), 23.65 (CH2(3)GABA), 21.30 (CH3PTSA) ppm; Mass Spectra (ESI): calculated values of C11H16NO2 ([M+H]+): 194.1181, measured value: 194.1167.

References

[1] Tetrahedron, 2017, vol. 73, # 50, p. 7073 - 7078
[2] Organic and Biomolecular Chemistry, 2009, vol. 7, # 11, p. 2327 - 2337
[3] RSC Advances, 2015, vol. 5, # 81, p. 66339 - 66354
[4] Patent: WO2014/59158, 2014, A1. Location in patent: Page/Page column 38-39
[5] Tetrahedron Letters, 2015, vol. 56, # 48, p. 6803 - 6806

H-GAMMA-ABU-OBZL P-TOSYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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H-GAMMA-ABU-OBZL P-TOSYLATE Suppliers

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View Lastest Price from H-GAMMA-ABU-OBZL P-TOSYLATE manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
4-Abu-obzl.tos 26727-22-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-03-29

26727-22-0, H-GAMMA-ABU-OBZL P-TOSYLATERelated Search:


  • H-GAMMA-ABU-OBZL P-TOSYLATE
  • H-GAMMA-ABU-OBZL TOS-OH
  • H-ABU(4)-OBZL TOS-OH
  • GAMMA-AMINOBUTYRIC ACID BENZYL ESTER P-TOSYLATE
  • GAMMA-AMINOBUTYRIC ACID-OBZL P-TOSYLATE
  • γ-Aminobutyric acid benzyl ester p-tosylate
  • Hγ-Abu-OBzl·p-tosylate
  • H-g-Abu-OBzl·TosOH
  • benzyl 4-aminobutanoate 4-methylbenzenesulfonate
  • gamma-Abu-OBzl p-tosylate
  • Hγ-Abu-OBzl·p-tosylate γ-AMinobutyric acid benzyl ester p-tosylate
  • H-GABA-OBzl · p-tosylate
  • H-g-Abu-OBzl · p-tosylate
  • H-γ-Abu-OBzl·TosOH
  • H-GABA-OBzl·TosOH
  • Benzyl gamma-aminobutyrate tosylate
  • benzyl 4-aminobutanoate para-toluene sulfonate
  • γ-Aminobutylic acid benzyl ester p-toluenesulfonate
  • 4-Abu-obzl.tos
  • 4-Aminobutyric acid benzyl ester p-tosylate
  • H-γ-Abu-Obzl.TosOH
  • γ-Aminobutyric acid benzyl ester p-tosylate
  • 26727-22-0
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