(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL

Product Name: (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
CAS No.: 139290-65-6
Chemical Name: (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
Synonyms: M 100907;MDL100907;R-MDL 100907;VOLINANSERIN;MDL 100907 NEW;MDL100907-L-tartrate;MDL100907 tartrate salt;MDL 100907 (MDL-100907;MDL-100907(Volinanserin);Volinanserin (MDL100907)
CBNumber: CB7103504
Molecular Formula: C22H28FNO3
Formula Weight: 373.46
MOL File: 139290-65-6.mol

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(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Property

Melting point:: 89-91°C
Boiling point:: 499.4±45.0 °C(Predicted)
Density: 1.150±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥20mg/mL
pka: 13.93±0.20(Predicted)
form: powder
color: off-white to light brown

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Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M3324
Product name: M100907
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $165
Updated: 2024/03/01

Sigma-Aldrich

Product number: M3324
Product name: M100907
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $693
Updated: 2024/03/01

Cayman Chemical

Product number: 15936
Product name: Volinanserin
Purity: ≥95%
Packaging: 1mg
Price: $55
Updated: 2024/03/01

Cayman Chemical

Product number: 15936
Product name: Volinanserin
Purity: ≥95%
Packaging: 5mg
Price: $144
Updated: 2024/03/01

Cayman Chemical

Product number: 15936
Product name: Volinanserin
Purity: ≥95%
Packaging: 10mg
Price: $263
Updated: 2024/03/01

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(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Chemical Properties,Usage,Production

Description

Volinanserin is a potent and selective antagonist of the serotonin receptor 5-HT_2A (K_i = 0.36-0.85 nM). It weakly binds 5-HT_2C, α₁-adrenergic, and sigma receptors (K_i = 88, 128, and 87 nM) and much less effectively associates with other serotonin, dopamine, adrenergic, muscarinic acetylcholine receptors and monoamine transporters. Volinanserin displays antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo.

Chemical Properties

Colourless solid

Uses

Volinanserin is a serotonin receptor 5-HT2A antagonist; anti-psychotic.

Uses

As a serotonin 5-HT2A receptor antagonist, Volinanserin Hydrochloride Salt can be used as potential controls in various biological studies.

General Description

M100907 blocks the serotonin 2A (5-HT2A) receptors and imposes antidepressant-like effects. It may be used for treating dopaminergic anomalies.

Biochem/physiol Actions

M100907 is a selective 5-HT2A Antagonist.

storage

+4°C

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL Suppliers

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139290-65-6, (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOLRelated Search:

4-(3-METHOXY-BENZYL)-PIPERIDINE ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL CHEMBRDG-BB 4010734 4-(2-METHOXY-BENZYL)-PIPERIDINE 3-PIPERIDIN-4-YLMETHYL-PHENOL PHENYL-PIPERIDIN-4-YL-METHANOL (R)-(+)-ALPHA-(3-HYDROXY-2-METHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL (+/-)-ALPHA-(2,3-DIMETHOXY-PHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINE-METHANOL Volinanserin Hydrochloride Salt

(+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

(aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

M 100907

R-MDL 100907

(R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol (R,R)-tartrate

4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R), (R,R)-tartrate

MDL100907-L-tartrate

(R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol

4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R)

MDL100907 tartrate salt

(+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride

(aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride

Volinanserin Hydrochloride Salt

(+)-α-(2,3-DiMethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidineMethanol Hydrochloride

(αR)-α-(2,3-DiMethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidineMethanol Hydrochloride

MDL-100907(Volinanserin)

(R)-(+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol

(R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol

4-piperidinemethanol, a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (ar)-

MDL100907

4-PIPERIDINEMETHANOL, 1-[2-(4-FLUOROPHENYL)ETHYL]-ALPHA-(2,3-DIMETHOXYPHENYL)-, (ALPHAR)

(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL

VOLINANSERIN

(R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol

MDL 100907 (MDL-100907

MDL 100907 NEW

Volinanserin (MDL100907)

Serotonin Receptor,inhibit,MDL 100907,5-HT Receptor,M-100907,5-hydroxytryptamine Receptor,Inhibitor,Volinanserin,M100907,MDL-100907

4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-

139290-65-6

C22H29ClFNO3

C22H28FNO3C4H6O6

C22H28FNO3

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals