BAMIFYLLINE

Product Name: BAMIFYLLINE
CAS No.: 2016-63-9
Chemical Name: BAMIFYLLINE
Synonyms: 8102CB;8102 CB;CB-8102;Bax-2739Z;Bamifyllin;BAMIFYLLINE;Bamiphylline;8-BENZYL-7-(2-(HYDROXYETHYL)AMINO)ETHYL)THEOPHYLLINE;8-benzyl-7-(2-(N-ethyl-2-hydroxyethylamino)ethyl)theophylline;8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
CBNumber: CB7103685
Molecular Formula: C20H27N5O3
Formula Weight: 385.46
MOL File: 2016-63-9.mol

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BAMIFYLLINE Property

Melting point:: 80-80.5°
Boiling point:: 619.0±65.0 °C(Predicted)
Density: 1.25
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 14.73±0.10(Predicted)
form: Solid
color: White to Pale Brown
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B119910
Product name: Bamifylline
Packaging: 1mg
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010768
Product name: BAMIFYLLINE
Purity: 95.00%
Packaging: 5MG
Price: $504.65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010768
Product name: BAMIFYLLINE
Purity: 95.00%
Packaging: 5G
Price: $3817.8
Updated: 2021/12/16

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BAMIFYLLINE Chemical Properties,Usage,Production

Originator

Bamifylline,ZYF Pharm Chemical

Uses

Bronchodilator.

Uses

Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.

Definition

ChEBI: Bamifylline is an oxopurine.

Manufacturing Process

A mixture of 100 kg of 8-benzyltheophilline, 36 L of N-ethylethanolamine, 300 L of 1,2-dichlorethane and 71 kg of sodium carbonate was refluxed for 24 hours. Then 36 L of N-ethylethanolamine was added and the reaction mixture was refluxed. After cooling to the mixture was added the water and hydrochloric acid. The organic phase was extracted with hydrochloric acid. The acidic phase was neutralized with sodium carbonate and the 7-(N-ethyl-N-β- hydroxyethylaminoethyl)-8-benzyltheophilline was extracted with dichloromethane. The solvent was evaporated and the free base of 7-(N-ethyl- N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was dissolved in methanol. Hydrochloride of 7-(N-ethyl-N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was obtained by addition to the solution the hydrochloric acid; yield 81%, melting point 185-186°C.

Therapeutic Function

Bronchodilator, Coronary vasodilator

BAMIFYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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BAMIFYLLINE Suppliers

China 27 Europe 2 France 1 Germany 1 India 1 South Korea 1 United Kingdom 4 United States 8 Global 45

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2016-63-9, BAMIFYLLINERelated Search:

Theophylline etamiphyllin BAMIFYLLINE 8-BENZYLTHEOPHYLLINE dimethazan AC 119 1-Methylcaffeine bamifylline hydrochloride ,BAMIFYLLINE HCL 7-(2-aminoethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione

BAMIFYLLINE

8-BENZYL-7-(2-(HYDROXYETHYL)AMINO)ETHYL)THEOPHYLLINE

8102 CB

8102CB

Bamiphylline

Bax-2739Z

CB-8102

8-benzyl-7-(2-(N-ethyl-2-hydroxyethylamino)ethyl)theophylline

8-benzyl-7-{2-[ethyl(2-hydroxyethyl)aMino]ethyl}-1,3-diMethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

1H-Purine-2,6-dione,7-[2-[ethyl(2-hydroxyethyl)aMino]ethyl]-3,7-dihydro-1,3-diMethyl-8-(phenylMethyl)-

7-[2-[Ethyl(2-hydroxyethyl)amino]ethyl]-3,7-dihydro-1,3-dimethyl-8-(phenylmethyl)-1H-purine-2,6-dione

Bamifyllin

Bamifylline HclQ: What is Bamifylline Hcl Q: What is the CAS Number of Bamifylline Hcl Q: What is the storage condition of Bamifylline Hcl

8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione

2016-63-9

C20H27N5O3