ChemicalBook > CAS DataBase List > Sabatolimab
Sabatolimab
- Product Name
- Sabatolimab
- CAS No.
- 2252262-24-9
- Chemical Name
- Sabatolimab
- Synonyms
- Sabatolimab;MBG453|||NVP-MBG453;Sabatolimab (anti-TIM-3);Research Grade Sabatolimab;Research Grade Sabatolimab(DHJ28402)
- CBNumber
- CB710616953
- Formula Weight
- 0
- MOL File
- Mol file
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Sabatolimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Sabatolimab Chemical Properties,Usage,Production
Uses
Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells[1].
target
TIM-3
References
[1] Andrew M. Brunner, et al. Efficacy and Safety of Sabatolimab (MBG453) in Combination with Hypomethylating Agents (HMAs) in Patients with Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (HR-MDS): Updated Results from a Phase 1b Study. Blood?(2020) 136 (Supplement 1): 1–2.
Sabatolimab Preparation Products And Raw materials
Raw materials
Preparation Products
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