N-Cyclohexyl-2-piperazin-1-yl-acetamide
- Product Name
- N-Cyclohexyl-2-piperazin-1-yl-acetamide
- CAS No.
- 64204-55-3
- Chemical Name
- N-Cyclohexyl-2-piperazin-1-yl-acetamide
- Synonyms
- C/63;Esaprazole;Esaprazole, 10 mM in DMSO;N-Cyclohexyl-2-piperazin-1-yl-ace;N-Cyclohexyl-1-piperazineacetamide;1-piperazineacetamide, N-cyclohexyl-;N-Cyclohexyl(piperazin-1-yl)acetamide;N-Cyclohexyl-2-piperazin-1-yl-acetamide;N-cyclohexyl-2-piperazin-1-ylacetamide dihydrochloride;{[(Piperazin-1-yl)acetyl]amino}cyclohexane, 1-[2-(Cyclohexylamino)-2-oxoethyl]piperazine
- CBNumber
- CB71074962
- Molecular Formula
- C12H23N3O
- Formula Weight
- 225.33
- MOL File
- 64204-55-3.mol
N-Cyclohexyl-2-piperazin-1-yl-acetamide Property
- Melting point:
- 111-112°
- Boiling point:
- bp0.5 190°
- Density
- 1.07±0.1 g/cm3(Predicted)
- pka
- 15.27±0.20(Predicted)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933599590
- Toxicity
- LD50 in mice (mg/kg): 1974 orally; 271 i.v.; in rats (mg/kg): 3900 orally (Corvi-Mora)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A621580
- Product name
- N-cyclohexyl-2-piperazin-1-ylacetamide
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- A621580
- Product name
- N-cyclohexyl-2-piperazin-1-ylacetamide
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H48-1-8C
- Product name
- N-Cyclohexyl-2-(piperazin-1-yl)acetamide
- Purity
- 98.0%
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- API0002597
- Product name
- ESAPRAZOLE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1147.43
- Updated
- 2021/12/16
- Product number
- 4H48-1-8C
- Product name
- N-Cyclohexyl-2-(piperazin-1-yl)acetamide
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $202
- Updated
- 2021/12/16
N-Cyclohexyl-2-piperazin-1-yl-acetamide Chemical Properties,Usage,Production
Uses
Esaprazole (Hexaprazole) is an antiulcer agent that has the effect of promoting the healing of peptic ulcer. Esaprazole can inhibit the secretion of gastric acid and pepsin[1].
in vivo
Esaprazole (50-450 mg/kg; intraduodenal administration; single dose) can inhibit the secretion of gastric acid and pepsin in a dose-dependent manner in Wistar rats. Moreover, Esaprazole (25, 50, and 100 mg/kg; intraperitoneal injection; single dose) can also inhibit the hypersecretion of acid induced by Bethanechol (HY-B0406) (500 μg/kg/h) and the acid secretory response induced by vagal stimulation[1].
References
[1] Blandizzi C, et al. Gastric antisecretory effects of esaprazole in rats. Digestion. 1992;51(4):226-232. DOI:10.1159/000200902
N-Cyclohexyl-2-piperazin-1-yl-acetamide Preparation Products And Raw materials
Raw materials
Preparation Products
N-Cyclohexyl-2-piperazin-1-yl-acetamide Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 21-619849051-1 18521059765
- synchempharma@aliyun.com
- Country
- China
- ProdList
- 6468
- Advantage
- 55
- Tel
- 025-58859352 13155353615
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15525
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- 15995034354
- purchase@chochem.cn
- Country
- China
- ProdList
- 2704
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58
- Tel
- 400-821-026
- Sales@sangon.com
- Country
- China
- ProdList
- 6710
- Advantage
- 58