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N-Cyclohexyl-2-piperazin-1-yl-acetamide

Product Name
N-Cyclohexyl-2-piperazin-1-yl-acetamide
CAS No.
64204-55-3
Chemical Name
N-Cyclohexyl-2-piperazin-1-yl-acetamide
Synonyms
C/63;Esaprazole;Esaprazole, 10 mM in DMSO;N-Cyclohexyl-2-piperazin-1-yl-ace;N-Cyclohexyl-1-piperazineacetamide;1-piperazineacetamide, N-cyclohexyl-;N-Cyclohexyl(piperazin-1-yl)acetamide;N-Cyclohexyl-2-piperazin-1-yl-acetamide;N-cyclohexyl-2-piperazin-1-ylacetamide dihydrochloride;{[(Piperazin-1-yl)acetyl]amino}cyclohexane, 1-[2-(Cyclohexylamino)-2-oxoethyl]piperazine
CBNumber
CB71074962
Molecular Formula
C12H23N3O
Formula Weight
225.33
MOL File
64204-55-3.mol
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N-Cyclohexyl-2-piperazin-1-yl-acetamide Property

Melting point:
111-112°
Boiling point:
bp0.5 190°
Density 
1.07±0.1 g/cm3(Predicted)
pka
15.27±0.20(Predicted)
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933599590
Toxicity
LD50 in mice (mg/kg): 1974 orally; 271 i.v.; in rats (mg/kg): 3900 orally (Corvi-Mora)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A621580
Product name
N-cyclohexyl-2-piperazin-1-ylacetamide
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
A621580
Product name
N-cyclohexyl-2-piperazin-1-ylacetamide
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-1-8C
Product name
N-Cyclohexyl-2-(piperazin-1-yl)acetamide
Purity
98.0%
Packaging
250mg
Price
$50
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002597
Product name
ESAPRAZOLE
Purity
95.00%
Packaging
2.5G
Price
$1147.43
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-1-8C
Product name
N-Cyclohexyl-2-(piperazin-1-yl)acetamide
Purity
98.0%
Packaging
1g
Price
$202
Updated
2021/12/16
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N-Cyclohexyl-2-piperazin-1-yl-acetamide Chemical Properties,Usage,Production

Uses

Esaprazole (Hexaprazole) is an antiulcer agent that has the effect of promoting the healing of peptic ulcer. Esaprazole can inhibit the secretion of gastric acid and pepsin[1].

in vivo

Esaprazole (50-450 mg/kg; intraduodenal administration; single dose) can inhibit the secretion of gastric acid and pepsin in a dose-dependent manner in Wistar rats. Moreover, Esaprazole (25, 50, and 100 mg/kg; intraperitoneal injection; single dose) can also inhibit the hypersecretion of acid induced by Bethanechol (HY-B0406) (500 μg/kg/h) and the acid secretory response induced by vagal stimulation[1].

References

[1] Blandizzi C, et al. Gastric antisecretory effects of esaprazole in rats. Digestion. 1992;51(4):226-232. DOI:10.1159/000200902

N-Cyclohexyl-2-piperazin-1-yl-acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Cyclohexyl-2-piperazin-1-yl-acetamide Suppliers

China 13 Germany 2 Ukraine 1 United Kingdom 2 United States 4 Global 22
CHESS GmbH
Tel
--
Fax
--
Email
chess-chemie@T-online.de
Country
Germany
ProdList
605
Advantage
65
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

64204-55-3, N-Cyclohexyl-2-piperazin-1-yl-acetamideRelated Search:

KP 103 N-(4-methylcyclohexyl)-2-(piperazin-1-yl)acetamide N-cyclohexyl-2-(piperazin-1-yl)propanamide AURORA 12628 N-CYCLOHEXYL-2-[4-(4,6-DIANILINO-1,3,5-TRIAZIN-2-YL)-1-PIPERAZINYL]ACETAMIDE 4-CYCLOHEXYLCARBAMOYLMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-(1-PHENYLCYCLOHEXYL)-2-PIPERAZIN-1-YLACETAMIDE N-Cyclohexyl-2-piperazin-1-yl-acetamide 2-(4-(BENZO[D]THIAZOL-2-YL)PIPERAZIN-1-YL)-N-CYCLOHEXYLACETAMIDE

  • N-Cyclohexyl(piperazin-1-yl)acetamide
  • N-Cyclohexyl-1-piperazineacetamide
  • 1-piperazineacetamide, N-cyclohexyl-
  • N-cyclohexyl-2-piperazin-1-ylacetamide dihydrochloride
  • {[(Piperazin-1-yl)acetyl]amino}cyclohexane, 1-[2-(Cyclohexylamino)-2-oxoethyl]piperazine
  • N-Cyclohexyl-2-piperazin-1-yl-acetamide
  • Esaprazole
  • N-Cyclohexyl-2-piperazin-1-yl-ace
  • C/63
  • Esaprazole, 10 mM in DMSO
  • 64204-55-3
  • piperazines