Description Uses Health Hazard Toxicology
ChemicalBook > CAS DataBase List > Cocamidopropyl betaine

Cocamidopropyl betaine

Description Uses Health Hazard Toxicology
Product Name
Cocamidopropyl betaine
CAS No.
61789-40-0
Chemical Name
Cocamidopropyl betaine
Synonyms
Coco Amido Propyl Betain;LAB-35;1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts;NAXAINE C;NorfoxCapb;NAXAINE CO;RALUFON 414;Lonzaine(R) C;Lonzaine(R) CO;TEGO BETAIN L7 OK
CBNumber
CB7109324
Molecular Formula
C19H38N2O3
Formula Weight
342.51662
MOL File
61789-40-0.mol
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Cocamidopropyl betaine Property

Boiling point:
104.3℃[at 101 325 Pa]
vapor pressure 
0Pa at 25℃
storage temp. 
Refrigerator
solubility 
Methanol (Sparingly), Water (Sparingly)
form 
Oil
color 
Colourless
Odor
at 100.00?%. bland
Water Solubility 
23.676g/L
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChI
InChI=1S/C19H38N2O3/c1-4-5-6-7-8-9-10-11-12-14-18(22)20-15-13-16-21(2,3)17-19(23)24/h4-17H2,1-3H3,(H-,20,22,23,24)
InChIKey
MRUAUOIMASANKQ-UHFFFAOYSA-N
SMILES
[O-]C(C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)=O
LogP
-1.28
EPA Substance Registry System
1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., inner salts (61789-40-0)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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Cocamidopropyl betaine Chemical Properties,Usage,Production

Description

Cocamidopropyl betaine (CAPB) is an amphoteric surfactant. The particular behaviour of amphoterics is related to their zwitterionic character; that means: both anionic and cationic structures are found in one molecule.

Uses

Cocamidopropyl betaine is widely used as a surfactant. The usage of cocamidopropyl betaine in personal-care products has grown in recent years due to its relative mildness compared with other surface active compounds. Cocamidopropyl betaine is widely used in various cosmetics like shampoos, bath products, and cleansing agents, shower gels, bath foam, liquid soaps, skin care products, hand wash detergents. Uses in household cleaning products, the scope of HERA, include laundry detergents, hand dishwashing liquids, and hard surface cleaners.

Health Hazard

Skin irritation: According to current OECD guideline, cocamidopropyl betaine (about 30% aqueous solution and nearly 80% spray-dried substance) is not a skin irritant. In human studies up to 3 % solutions were weakly irritating. Impurities like amidoamine may contribute to the irritation reaction. The irritating properties of sodium lauryl sulphate formulations could be significantly reduced by the addition of cocamidopropyl betaine.
Eye irritation: The concentrated and the 25 - 30 % active cocamidopropyl betaine is an irreversible eye irritant. The 15 % concentrations were irritating to highly irritating. At and below 10% active dilution studies show a mild to moderate and reversible eye irritating potential of cocamidopropyl betaine.

Toxicology

The acute oral and dermal toxicity of cocamidopropyl betaine 30 – 35.5 % active solution in rats is low. The LD50 (dermal) is > 2000 mg/kg bw (which was the highest dose applied), LD50 (oral) is ≥ 4900 mg/kg bw. There were no clinical signs reported after acute dermal exposure; after oral exposure to high doses, decreased motor activity, diarrhea, and ataxia as well as signs of gastrointestinal irritation were found.

Chemical Properties

Liquid

Chemical Properties

Cocamidopropyl Betaine (CAB) is an organic compound derived from coconut oil and dimethylaminopropylamine. It is a zwitterion, consisting of both a quaternary ammonium cation and a carboxylate. CAB is available as viscous pale yellow solution that is used as a surfactant in personal care products.

Characteristics

Cocamidopropyl Betaine (CAB) is perfectly compatible with anionic, cationic and nonionic surfactants, it can still be used as cloudy point inhibitor.
CAB can produce rich and fine foams. Fonnulated with adequate proportion of anionic surfactant, it has significant thickening effect.
CAB has excellent to tolerance to skin, effectively reduce the irritation caused by fatty alcohol sulfate or fatty alcohol ether sulfate in the products.
CAB has antibiotic function, being a good additive in personal sanitary products. CAB has excellent antistatic function, being an ideal conditioning agent.

Uses

Lonzaine(R) CO is a mild, high foaming, biodegradable cocoamidopropyl betaines. Suggested applications: foam booster for shampoos.

Uses

Cocamidopropyl betaine is a surfactant in liquid soaps, shampoos, hair colorants, shower and bath formulations.

Definition

ChEBI: A mixture of carboxamidopropyl betaines derived from fatty acids of varying chain lengths. The principal component is lauramidopropyl betaine.

Application

Cocamidopropyl betaine is used in cosmetics and personal hygiene products (eg, shampoos, contact lens solutions, toothpaste detergents, makeup removers, bath gels, skin care products, cleansers, liquid soaps, antiseptics, and gynecologic and anal hygiene products).

Hazard

A severe eye irritant.

Flammability and Explosibility

Not classified

Contact allergens

Cocamidopropyl betaine is a pseudo-amphoteric zwitterion detergent derived from long-chain alkylbetaines. It is available from many suppliers under more than 50 trade names (including Tego-betain L7 and Ampholyt JB 130). Exposure occurs via rinse-off products such as liquid soaps, shampoos, and shower gels, but also via leave-on products (for example, roll-on deodorant). Occupational sources are mainly in hairdressing. The first synthesis step consists of the reaction of coconut fatty acids with 3-dimethylaminopropylamine, giving cocamidopropyl dimethylamine. This amido amine is converted into cocamidopropyl betaine by reaction with sodium monochloroacetate. Both dimethylaminopropylamine and cocamidopropyl dimethylamine are thought to be the sensitizers.

storage

In the original sealed containers and at temperature between 0°C and 40°C, this product remains stable at least one year. On account during its high salt content the product can have a Corrosive effect during storage in stainless steel tanks.

Cocamidopropyl betaine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cocamidopropyl betaine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Cocamidopropyl Betaine/CAB/LAB 61789-40-0
Price
US $60.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-19
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Lauroamide propyl betaine 61789-40-0
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-09
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cocamidopropyl betaine 61789-40-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-10

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