ChemicalBook > CAS DataBase List > DECOYININE

DECOYININE

Product Name
DECOYININE
CAS No.
2004-04-8
Chemical Name
DECOYININE
Synonyms
a14;U-7984;decoyinin;DECOYININE;angustmycina;antibiotica14;Decoyinine (U-7984);Decoyinine, 10 mM in DMSO;Decoyinine [AngustMycin A];5,6-Psicofuranosenyladenine
CBNumber
CB7109485
Molecular Formula
C11H13N5O4
Formula Weight
279.25
MOL File
2004-04-8.mol
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DECOYININE Property

Melting point:
198-200℃
Boiling point:
639.8±65.0 °C(Predicted)
Density 
1.87±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble
form 
A crystalline solid
pka
12.90±0.60(Predicted)
color 
White to off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13851
Product name
Decoyinine
Packaging
1mg
Price
$97
Updated
2024/03/01
Cayman Chemical
Product number
13851
Product name
Decoyinine
Packaging
10mg
Price
$593
Updated
2021/12/16
Cayman Chemical
Product number
13851
Product name
Decoyinine
Packaging
5mg
Price
$410
Updated
2024/03/01
Usbiological
Product number
207146
Product name
Decoyinine
Packaging
1mg
Price
$307
Updated
2021/12/16
TRC
Product number
D226825
Product name
Decoyinin
Packaging
2.5mg
Price
$810
Updated
2021/12/16
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DECOYININE Chemical Properties,Usage,Production

Uses

Decoyinin, is a Xanthosine monophosphate (XMP) aminase inhibitor and GMP synthetase inhibitor. It can also be used to study the inhibition of cell wall synthesis, to inhibit RNA synthesis, to lower intracellular GTP levels in Streptococcus mutans.

Definition

ChEBI: Decoyinine is a member of 6-aminopurines.

in vivo

It is showed that Decoyinine (Angustmycin A) treatment hinders tumor growth in xenograft mouse model. Moreover, like GMPS activity, the effect of Decoyinine does not appear to be subtype specific as it impairs growth of xenografts from cells harboring NRASQ61R (SK-Mel-103) or BRAFV600E (SK-Mel-28) mutations[1].

DECOYININE Preparation Products And Raw materials

Raw materials

Preparation Products

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2004-04-8, DECOYININERelated Search:


  • 9-(6-Deoxy-β-D-erythro-5-hexeno-2-furanulonosyl)-9H-purin-6-amine
  • (2R,3R,4S)-2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylideneoxolane-3,4-diol
  • (2R,3R,4S)-2-(6-aminopurin-9-yl)-5-methylene-2-methylol-tetrahydrofuran-3,4-diol
  • (2R,3R,4S)-2-(6-azanylpurin-9-yl)-2-(hydroxymethyl)-5-methylidene-oxolane-3,4-diol
  • Decoyinine [AngustMycin A]
  • 5,6-Psicofuranosenyladenine
  • 9-(6-Deoxy-D-β-erythro-hex-5-en-2-ulofuranosyl)adenine
  • Decoyinine (U-7984)
  • 9H-Purin-6-amine, 9-(6-deoxy-β-D-erythro-hex-5-en-2-ulofuranosyl)-
  • antibiotica14
  • decoyinin
  • DECOYININE
  • U-7984
  • 9-(6-deoxy-beta-d-erythro-hex-5-en-2-ulofuranosyl)-9h-purin-6-amin
  • 9-(6-deoxy-beta-d-erythro-hex-5-enulofuranosyl)-adenin
  • 9-(6-deoxy-beta-d-erythro-hex-5-enulofuranosyl)adenine
  • 9-(tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)-adenin
  • 9-(tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)adenine
  • a14
  • angustmycina
  • Adenosine, 4',5'-didehydro-1'-C-(hydroxymethyl)-
  • 4',5'-didehydro-1'-C-(hydroxymethyl)-adenosine
  • (2R,3R,4S)-2-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-5-methylenetetrahydrofuran-3,4-diol
  • (2R,3R,4S)-2-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-5-methylideneoxolane-3,4-diol
  • Decoyinine (Augustmycin A), Nucleoside analog
  • Decoyinine, 10 mM in DMSO
  • 2004-04-8
  • C10H11N5O4