N-boc Asp(OH)Ome

Product Name: N-boc Asp(OH)Ome
CAS No.: 98045-03-5
Chemical Name: N-boc Asp(OH)Ome
Synonyms: Boc-L-Asp-Ome;N-boc Asp(OH)Ome;1-Methyl N-Boc-L-aspartate;(Tert-Butoxy)Carbonyl Asp-OMe;Boc-L-aspartic acid 1-methyl ester;N-Boc-L-aspartic Acid 1-Methyl Ester;N-Boc-L-aspartic acid 1-Methyl ester, 98%;α-methyl N-(tert-butoxycarbonyl)aspartate;1-Methyl N-(tert-Butoxycarbonyl)-L-aspartate;N-tert-Butoxycarbonyla spartic acid a-methylester
CBNumber: CB71096083
Molecular Formula: C10H17NO6
Formula Weight: 247.25
MOL File: 98045-03-5.mol

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N-boc Asp(OH)Ome Property

Melting point:: 79-81℃
Boiling point:: 407.1±40.0 °C(Predicted)
Density: 1.209
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 4.09±0.19(Predicted)
form: Solid
color: White to Almost white

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Safety

HS Code: 2924.19.8000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2970
Product name: 1-Methyl N-(tert-Butoxycarbonyl)-L-aspartate
Purity: >97.0%(HPLC)(T)
Packaging: 5g
Price: $57
Updated: 2025/07/31

TRC

Product number: B657183
Product name: Boc-Asp-OMe
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB72153
Product name: Boc-Asp-OMe
Packaging: 25g
Price: $68
Updated: 2021/12/16

Oakwood

Product number: M06171
Product name: Boc-Asp-Ome
Packaging: 25g
Price: $79
Updated: 2021/12/16

Chem-Impex

Product number: 24636
Product name: Boc-Asp-OMe,99%(HPLC)
Purity: 99%(HPLC)
Packaging: 25G
Price: $84
Updated: 2021/12/16

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N-boc Asp(OH)Ome Chemical Properties,Usage,Production

Uses

N-Boc-L-aspartic acid 1-methyl ester is used as an intermediate in the preparation of modified alfa-amino acids and 5-cis-alkylprolines.

Synthesis

80963-12-8

98045-03-5

Boc-L-aspartyl (OBn)(OMe)14 (5.88 g, 17.43 mmol) was dissolved in methanol (20 mL) in a 50 mL round-bottomed flask and 10% palladium carbon catalyst was added under nitrogen protection. The reaction system was replaced three times with nitrogen and then three times with hydrogen. Subsequently, the reaction mixture was stirred under hydrogen atmosphere and atmospheric pressure for 6 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target product (S)-3-((tert-butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid (Compound 15) in the form of a colorless gel (4.1 g, 95% yield). The specific optical rotation [α]21D of the product was 34 (c 0.1, CHCl3).1H NMR (CDCl3, 400 MHz) δ: 1.43 (s, 9H), 2.83-2.86 (d, 1H, J = 16.92 Hz), 3.01-3.05 (d, 1H, J = 16.68 Hz), 3.74 (s, 3H), 4.57 (s , 1H), 5.55-5.57 (d, 1H, J = 8.12 Hz), 10.45 (s, 1H).13C NMR (CDCl3, 100 MHz) δ: 28.3, 36.6, 49.7, 52.8, 80.5, 155.5, 171.5, 176.0. IR (KBr) ν: 3366, 2980, 1719 , 1506, 1440, 1395, 1368, 1222, 1165, 1060, 1008, 864, 764, 587 cm-1.

References

[1] Organic and Biomolecular Chemistry, 2007, vol. 5, # 9, p. 1459 - 1465
[2] Tetrahedron Letters, 2014, vol. 55, # 14, p. 2274 - 2276
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 1, p. 15 - 20
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 2, p. 586 - 590
[5] Carbohydrate Research, 2013, vol. 382, p. 36 - 42

N-boc Asp(OH)Ome Preparation Products And Raw materials

Raw materials

Preparation Products

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N-boc Asp(OH)Ome Suppliers

Americas 1 China 84 Europe 1 India 1 Japan 3 United Kingdom 1 United States 7 Global 98

Alfa Aesar

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Energy Chemical

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ChemPep, Inc.

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Shanghai Sphchem Co., Ltd.

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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View Lastest Price from N-boc Asp(OH)Ome manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-L-Asp-Ome 98045-03-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-24

Career Henan Chemical Co

Product: N-boc Asp(OH)Ome 98045-03-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-03

98045-03-5, N-boc Asp(OH)OmeRelated Search:

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N-Boc-L-aspartic acid 1-Methyl ester, 98%

N-boc Asp(OH)Ome

N-[(1,1-Dimethylethoxy)carbonyl]-L-aspartic acid alpha-methyl ester

N-tert-Butoxycarbonyl-L-aspartic acid 1-methyl ester

Boc-L-aspartic acid 1-methyl ester

1-Methyl N-(tert-Butoxycarbonyl)-L-aspartate

(Tert-Butoxy)Carbonyl Asp-OMe

N-tert-Butoxycarbonyla spartic acid a-methylester

α-methyl N-(tert-butoxycarbonyl)aspartate

(3S)-3-{[(tert-butoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid

(S)-3-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoicacid

L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-methyl ester

1-Methyl N-Boc-L-aspartate

Boc-L-Asp-Ome

N-tert-Butoxycarbonylaspartic acid α-methyl ester

N-Boc-L-aspartic Acid 1-Methyl Ester

98045-03-5