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prifuroline

Product Name
prifuroline
CAS No.
70833-07-7
Chemical Name
prifuroline
Synonyms
prifuroline;3-(benzofuran-2-yl)-N,N-dimethyl-3,4-dihydro-2H-pyrrol-5-amine;3-(Benzofuran-2-yl)-3,4-dihydro-N,N-dimethyl-2H-pyrrol-5-amine;2H-Pyrrol-5-amine, 3-(2-benzofuranyl)-3,4-dihydro-N,N-dimethyl-;3-(benzofuran-2-yl)-N,N-dimethyl-3,4-dihydro-2H-pyrrol-5-amine(WXC06062)
CBNumber
CB71116538
Molecular Formula
C14H16N2O
Formula Weight
228.29
MOL File
70833-07-7.mol
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prifuroline Property

Boiling point:
383.8±31.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
8.55±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0016654
Product name
PRIFUROLINE
Purity
95.00%
Packaging
5MG
Price
$503.27
Updated
2021/12/16
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prifuroline Chemical Properties,Usage,Production

Uses

Prifuroline is an antiarrhythmic agent.

in vivo

Prifuroline is an antiarrhythmic agent. Prifuroline dose-dependently antagonizes the arrhythmogenic action of aconitine in rats, when administered either intravenously (5, 10 or 20 mg/kg) or intraduodenally (10, 20 or 50 mg/kg). Prifuroline also diminishes ventricular susceptibility to electrical stimulation in open-chest rats. The arrhythmias induced in dogs by coronary artery ligation are markedly antagonized by Prifuroline after doses of 5 and 10 mg/kg i.v. or 30 mg/kg intraduodenally. The duration of its antiarrhythmic activity in this model of arrhythmias in conscious dogs is much longer after intraduodenal than after i.v. administration[1].

References

[1] Benharkate M, et al. Antiarrhythmic and hemodynamic effects of prifuroline. Arzneimittelforschung. 1986 Dec;36(12):1761-7. PMID:3566836

prifuroline Preparation Products And Raw materials

Raw materials

Preparation Products

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prifuroline Suppliers

TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.
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70833-07-7, prifurolineRelated Search:


  • 3-(Benzofuran-2-yl)-3,4-dihydro-N,N-dimethyl-2H-pyrrol-5-amine
  • 3-(benzofuran-2-yl)-N,N-dimethyl-3,4-dihydro-2H-pyrrol-5-amine
  • 3-(benzofuran-2-yl)-N,N-dimethyl-3,4-dihydro-2H-pyrrol-5-amine(WXC06062)
  • prifuroline
  • 2H-Pyrrol-5-amine, 3-(2-benzofuranyl)-3,4-dihydro-N,N-dimethyl-
  • 70833-07-7