5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER

Product Name: 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.: 60298-18-2
Chemical Name: 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms: Ethyl5-oxopyrrolidine-3-carboxylate;Ethyl 2-oxopyrrolidine-4-carboxylate;Ethyl 5-oxo-3-pyrrolidinecarboxylate;Ethyl2-oxopyrrolidine-4-carboxylate,96%;Ethyl 2-oxopyrrolidine-4-carboxylate 95+%;5-oxo-3-pyrrolidinecarboxylic acid ethyl ester;2-Oxo-pyrrolidine-4-carboxylic acid ethyl ester;3-Pyrrolidinecarboxylic acid, 5-oxo-, ethyl ester
CBNumber: CB71118956
Molecular Formula: C7H11NO3
Formula Weight: 157.17
MOL File: 60298-18-2.mol

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5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER Property

Melting point:: 40-47℃
Boiling point:: 312.7±35.0 °C(Predicted)
Density: 1.161±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: Solid
pka: 15.39±0.40(Predicted)
color: Pale brown to dark brown

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Safety

WGK Germany: 1
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 721549
Product name: Ethyl 5-oxopyrrolidine-3-carboxylate
Purity: 95%
Packaging: 500mg
Price: $40.3
Updated: 2023/06/20

Matrix Scientific

Product number: 119135
Product name: Ethyl 5-oxopyrrolidine-3-carboxylate
Purity: 95+%
Packaging: 1g
Price: $288
Updated: 2021/12/16

AK Scientific

Product number: 8987AB
Product name: Ethyl 5-oxopyrrolidine-3-carboxylate
Packaging: 5g
Price: $531
Updated: 2021/12/16

Matrix Scientific

Product number: 119135
Product name: Ethyl 5-oxopyrrolidine-3-carboxylate
Purity: 95+%
Packaging: 5g
Price: $864
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027497
Product name: 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER
Purity: 95.00%
Packaging: 100G
Price: $5457.38
Updated: 2021/12/16

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5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

87121-89-9

60298-18-2

GENERAL METHOD: To a solution of ethyl 3-oxocyclobutanecarboxylate (100 mg, 0.45 mmol) in dichloromethane (3.8 mL) was slowly added hydrogen chloride (2 M, 1.4 mL) at room temperature. Subsequently, O- homotrimethylbenzenesulfonylhydroxylamine (2.00 equiv, 2.0000) was added and the reaction mixture was stirred for 3 hours. After completion of the reaction, saturated NaHCO3 solution was added for neutralization and the organic layer was extracted with dichloromethane. The organic layers were combined, dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure. The crude product was purified by rapid chromatography on silica gel to afford ethyl 5-oxopyrrolidine-3-carboxylate (87 mg, 0.802 mmol, 80% yield) as a white solid.

References

[1] Tetrahedron Letters, 2018, vol. 59, # 20, p. 1896 - 1901

5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

China 41 India 2 United Kingdom 1 United States 8 Global 52

Pure Chemistry Scientific Inc.

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Sigma-Aldrich

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View Lastest Price from 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: ethyl 5-oxopyrrolidine-3-carboxylate 60298-18-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER 60298-18-2
Price: US $1.00/KG
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-10

60298-18-2, 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER Related Search:

MFCD22689490 ethyl 1-benzyl-4,5-dioxopyrrolidine-3-carboxylate 5-OXO-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER Ethyl 2-Methyl-4-oxopyrrolidine-1-carboxylate (R)-2,5-dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)aMino)-3-(phenylthio)propanoate 2-Methyl-3-oxo-1-Pyrrolidinecarboxylic acid ethyl ester Ethyl N-Boc-3-oxopyrrolidine-2-carboxylate Ethyl N-Cbz-4-Oxopyrrolidine-3-carboxylate METHYL 5-OXOPYRROLIDINE-3-CARBOXYLATE ethyl 1-(2,5-dioxopyrrolidin-3-yl)piperidine-4-carboxylate 4-[3-(isopropylamino)-2,5-diketo-pyrrolidin-1-yl]benzoic acid ethyl ester 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER ETHYL 1-ETHYL-4,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, 97 ETHYL 1-(2-FURYLMETHYL)-4,5-DIOXOPYRROLIDINE-3-CARBOXYLATE 2-(DANSYLSULFONAMIDO)ETHYL-3-(N-SULFOSUCCINIMIDYLCARBOXY)ETHYL DISULFIDE, SODIUM SALT ETHYL 1-(TERT-BUTYL)-4,5-DIOXOPYRROLIDINE-3-CARBOXYLATE 2-[(N2-[N6-(4-AZIDO-2,3,5,6-TETRAFLUOROBENZOYL)-6-AMINOCAPROYL]-N6-(6-BIOTINAMIDOCAPROYL)-L-LYSINYLAMIDO)] ETHYL 2-(N-SULFOSUCCINIMYDYLCARBOXY)ETHYL DISULFIDE, SODIUM SALT 2-[N2-(4-AZIDO-2,3,5,6-TETRAFLUOROBENZOYL)-N6-(6-BIOTINAMIDOCAPROYL)-L-LYSINYL]ETHYL 2'- (N-SULFOSUCCINIMIDYLCARBOXY)ETHYL DISULFIDE, SODIUM SALT

Ethyl5-oxopyrrolidine-3-carboxylate

3-Pyrrolidinecarboxylic acid, 5-oxo-, ethyl ester

Ethyl 2-oxopyrrolidine-4-carboxylate

2-Oxo-pyrrolidine-4-carboxylic acid ethyl ester

Ethyl 2-oxopyrrolidine-4-carboxylate 95+%

5-oxo-3-pyrrolidinecarboxylic acid ethyl ester

Ethyl2-oxopyrrolidine-4-carboxylate,96%

Ethyl 5-oxo-3-pyrrolidinecarboxylate

60298-18-2