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Dinalin

Product Name
Dinalin
CAS No.
58338-59-3
Chemical Name
Dinalin
Synonyms
Dinalin;GOE1734;dinaline;PD-104208;Dinaline, Antineoplastic agent;Benzamide, 4-amino-N-(2-aminophenyl)-
CBNumber
CB71178530
Molecular Formula
C13H13N3O
Formula Weight
227.26
MOL File
58338-59-3.mol
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Dinalin Property

Melting point:
180.5°C
Boiling point:
368.98°C (rough estimate)
Density 
1.1267 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
Store at Room Tem.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0001967
Product name
4-AMINO-N-(2-AMINOPHENYL)-BENZAMIDE
Purity
95.00%
Packaging
5MG
Price
$504.2
Updated
2021/12/16
Acrotein
Product number
AM-0721
Product name
4-Amino-N-(2-aminophenyl)-benzamide
Purity
97%
Packaging
1g
Price
$275
Updated
2021/12/16
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Dinalin Chemical Properties,Usage,Production

Uses

Dinaline (GOE 1734; PD 104 208; NSC 328786) is a potent and orally activity anticancer agent. Dinaline shows cytotoxicity and antitumor activity. Dinaline has the potential for the research of colorectal cancer[1].

in vivo

Dinaline (5.9, 7.7, 10 mg/kg; p.o.; 5 days per week for 10 weeks) inhibits tumor growth in rats[1].

Animal Model:140-160 g, male Sprague-Dawley rats[1]
Dosage:5.9, 7.7, 10 mg/kg
Administration:P.o.; 5 days per week for 10 weeks
Result:Showed significant tumor growth inhibition in a dose-dependent manner with the ratio of median tumor volume of (T/C%) values of 0.4, 16 and 10.6 at 10, 7.7 and 5.9 mg/kg respectively.

References

[1] Seelig MH, et al. Efficacy of dinaline and its methyl and acetyl derivatives against colorectal cancer in vivo and in vitro. Eur J Cancer. 1996 Oct;32A(11):1968-76. DOI:10.1016/0959-8049(96)00217-1

Dinalin Preparation Products And Raw materials

Raw materials

Preparation Products

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Dinalin Suppliers

Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Abcam Limited
Tel
--
Fax
--
Email
us.orders@abcam.com
Country
United States
ProdList
6001
Advantage
50

58338-59-3, DinalinRelated Search:


  • Dinalin
  • dinaline
  • GOE1734
  • PD-104208
  • Benzamide, 4-amino-N-(2-aminophenyl)-
  • Dinaline, Antineoplastic agent
  • 58338-59-3