BOC-GLU-OME

Product Name: BOC-GLU-OME
CAS No.: 72086-72-7
Chemical Name: BOC-GLU-OME
Synonyms: BOC-L-GLU-OME;Boc-L-Glutamic Acid 5-Methyl Ester;BOC-GLU-OME;BOC-GLUTAMIC ACID-OME;BOC-GLU-OME USP/EP/BP;(Tert-Butoxy)Carbonyl Glu-OMe;Boc-L-glutamicacida-methylester;BOC-L-GLUTAMIC ACID METHYL ESTER;Boc-L-glutamic acid 1-methyl ester;Boc-L-glutamic acid α-methyl ester
CBNumber: CB7119473
Molecular Formula: C11H19NO6
Formula Weight: 261.27
MOL File: 72086-72-7.mol

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BOC-GLU-OME Property

Melting point:: 119-123℃
Boiling point:: 428.4±40.0 °C(Predicted)
Density: 1.182±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 4.48±0.10(Predicted)
color: Off-White to Light Yellow
InChI: InChI=1S/C11H19NO6/c1-11(2,3)18-10(16)12-7(9(15)17-4)5-6-8(13)14/h7H,5-6H2,1-4H3,(H,12,16)(H,13,14)/t7-/m0/s1
InChIKey: ZAYAFKXUQMTLPL-ZETCQYMHSA-N
SMILES: C(OC)(=O)[C@H](CCC(O)=O)NC(OC(C)(C)C)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B656110
Product name: N-Boc-L-glutamicAcidα-MethylEster
Packaging: 5g
Price: $155
Updated: 2021/12/16

TRC

Product number: B656110
Product name: N-Boc-L-glutamicAcidα-MethylEster
Packaging: 50g
Price: $820
Updated: 2021/12/16

TRC

Product number: B656110
Product name: N-Boc-L-glutamicAcidα-MethylEster
Packaging: 100g
Price: $1335
Updated: 2021/12/16

AK Scientific

Product number: W8083
Product name: Boc-Glu-OMe
Packaging: 100g
Price: $1002
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0010781
Product name: BOC-GLU-OME
Purity: 95.00%
Packaging: 1G
Price: $640
Updated: 2021/12/16

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BOC-GLU-OME Chemical Properties,Usage,Production

Chemical Properties

White to off-white crystalline powder

Uses

N-Boc-L-glutamic Acid α-Methyl Ester is a glutamate derivative that undergoes vitamin K-dependent carboxylation in liver microsomes.

Synthesis

59279-58-2

72086-72-7

The general procedure for the synthesis of (S)-4-((tert-butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid from methyl (S)-5-benzyl-2-((tert-butoxycarbonyl)amino)pentanedioate was as follows: methyl (S)-5-benzyl-2-((tert-butoxycarbonyl)amino)pentanedioate (4.95 g, 14.09 mmol) was dissolved in 50 mL of a round bottom flask of methanol (20 mL) and 10% palladium/carbon catalyst was added under nitrogen protection. Subsequently, the reaction vessel was purged three times with nitrogen and hydrogen alternately. The reaction mixture was stirred for 6 hours under hydrogen atmosphere and atmospheric pressure. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target compound (S)-4-((tert-butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid as a colorless gelatinous liquid (3.5 g, 96% yield). The specific optical rotation of the product [α]21D = +7 (c 0.1, CHCl3). Nuclear magnetic resonance hydrogen spectrum (1H NMR, CDCl3, 400 MHz) δ: 1.4 (s, 9H), 1.87-1.96 (m, 1H), 2.12-2.15 (m, 1H), 2.35-2.49 (m, 2H), 3.71 (s, 3H), 4.31-4.33 (d, 1H, J = 4.64 Hz), 5.24- 5.27 (d, 1H, J = 8.16 Hz), 10.19 (s, 1H). Nuclear magnetic resonance carbon spectrum (13C NMR, CDCl3, 100 MHz) δ: 27.5, 28.2, 30.0, 52.4, 52.8, 80.2, 155.5, 172.8, 177.7. infrared spectrum (IR, KBr) νmax: 3346, 2979, 1719, 1520, 1439, 1394, 1369. 1216, 1167, 1057, 1029, 879, 853, 816, 780, 596, 463 cm-1.

References

[1] Tetrahedron Letters, 1998, vol. 39, # 15, p. 2099 - 2102
[2] Organic and Biomolecular Chemistry, 2007, vol. 5, # 9, p. 1459 - 1465
[3] Chemical Communications, 2005, # 37, p. 4652 - 4654
[4] Tetrahedron Letters, 2014, vol. 55, # 14, p. 2274 - 2276
[5] Heterocycles, 2015, vol. 90, # 2, p. 1309 - 1316

BOC-GLU-OME Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-GLU-OME Suppliers

Canada 1 China 138 Germany 2 India 2 Japan 2 Switzerland 1 United Kingdom 2 United States 11 Global 159

Hangzhou Mingma Technology Co., LTD

Tel: 17621758100
Email: sales@sunmatech.com
Country: China
ProdList: 121
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Sichuan Ampebiochem Co., Ltd.

Tel: 028-65294243 13981822079;18682730901
Email: sales@ampebiochem.com
Country: China
ProdList: 1000
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Chengdu ruihede Medical Technology Co., Ltd

Tel: 17381862311; 17381862311
Email: sales2@ruihede.cn
Country: China
ProdList: 281
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
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Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
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View Lastest Price from BOC-GLU-OME manufacturers

Career Henan Chemical Co

Product: BOC-GLU-OME 72086-72-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-16

72086-72-7, BOC-GLU-OMERelated Search:

BOC-GLU(OME)-OME Boc-L-Glutamic acid 1-benzyl ester Boc-L-glutamic acid 1-tert-butyl ester BOC-GLU(OME)-OH BOC-GLU(OME)-OH DCHA,Boc-glu(ome)-ohcha,Boc-Glu(OMe)-OH&#8226 L-Glutamic acid Boc-L-Glutamic acid BOC-GLU(OBZL)-ONP BOC-GLU(OSU)-OBZL BOC-GLU-OME Boc-L-glutamic acid γ-benzyl ester N-carboxyanhydride BOC-GLU(OSU)-OTBU BOC-GLU(OTBU)-OBZL BOC-L-GLUTAMIC ACID DIBENZYL ESTER Boc-Glu-OCHEX BOC-L-GLU(OCHX)-O-CH2-PHI-CH2-COOH BOC-GLU(OTBU)-ONP BOC-GLU-PHENYL ESTER

BOC-L-GLU-OME

(4S)-5-methoxy-4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-5-oxopentanoic acid

(4S)-4-{[(tert-butoxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid

N-Boc-L-glutamic Acid alpha-Methyl Ester

N-BOC-L-glutamic acid 1-methyl ester

(S)-4-((tert-Butoxy(hydroxy)methylene)amino)-5-methoxy-5-oxopentanoic acid

Boc-L-glutamic acid α-methyl ester≥ 98% (HPLC)

(Tert-Butoxy)Carbonyl Glu-OMe

Boc-Glu-Ome (S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid

BOC-L-GLUTAMIC ACID METHYL ESTER

BOC-L-GLUTAMIC ACID ALPHA-METHYL ESTER

BOC-GLU-OME

BOC-GLUTAMIC ACID-OME

N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID ALPHA-METHYL ESTER

L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-,1-methyl ester

Boc-L-glutamicacida-methylester

Boc-L-Glutamic Acid 5-Methyl Ester

N-(tert-Butoxycarbonyl)glutamicacidmethylester

(S)-4-(tert-butoxycarbonylamino)-5-methoxy-5-oxopentanoic acid

Boc-L-glutamic acid 1-methyl ester

(2S)-2-[(tert-Butoxycarbonyl)amino]-5-methoxy-5-oxopentanoic acid

N-(tert-Butoxycarbonyl)glutamicacid a-methyl ester

N-[(1,1-imethylethoxy)carbonyl]-L-Glutamic acid 1-methyl ester

N-Boc-L-glutaMic Acid α-Methyl Ester

(4S)-5-methoxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoicaci

BOC-GLU-OME USP/EP/BP

Boc-L-glutamic acid α-methyl ester

(4S)-5-methoxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid

1-Methyl hydrogen N-[(1,1-dimethylethoxy)carbonyl]-L-glutamate

N-Boc-L-glutamic Acid α-Methyl Ester

1-Methyl hydrogen N-N-BOC-L-glutamate

72086-72-7

Amino Acids & Derivatives

Enzyme substrates