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NORBUPRENORPHINE

Product Name
NORBUPRENORPHINE
CAS No.
78715-23-8
Chemical Name
NORBUPRENORPHINE
Synonyms
NORBUPRENORPHINE;N-Desalkylbuprenorphin;N-Dealkylbuprenorphine;Norbuprenorphine (CRM);Toremifene Impurity 19;N-Desalkylbuprenorphine;Buprenorphine Impurity B;Norbuprenorphine solution;N-De(cyclopropylmethyl)buprenorphine;N-Des(cyclopropylmethyl)buprenorphine
CBNumber
CB7121849
Molecular Formula
C25H35NO4
Formula Weight
413.55
MOL File
78715-23-8.mol
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NORBUPRENORPHINE Property

Melting point:
221-224°C
Boiling point:
562.7±50.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Sparingly), Methanol (Slightly)
pka
9.14±0.60(Predicted)
form 
A neat solid
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
16-36/37-45-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N-912
Product name
Norbuprenorphine solution
Purity
100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$32.8
Updated
2022/05/15
Sigma-Aldrich
Product number
N-059
Product name
Norbuprenorphine solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$363
Updated
2022/05/15
Cayman Chemical
Product number
20127
Product name
Norbuprenorphine (CRM)
Packaging
100μg
Price
$36
Updated
2023/06/20
Cayman Chemical
Product number
15897
Product name
Norbuprenorphine
Purity
≥98%
Packaging
1mg
Price
$118
Updated
2023/06/20
Cayman Chemical
Product number
15897
Product name
Norbuprenorphine
Purity
≥98%
Packaging
5mg
Price
$471
Updated
2023/06/20
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NORBUPRENORPHINE Chemical Properties,Usage,Production

Description

Norbuprenorphine (CRM) (Item No. 20127) is a certified reference material categorized as an opioid. It is a major active metabolite of buprenorphine (Item Nos. 14025 | ISO60178). This product is intended for research and forensic applications.

Chemical Properties

Light Brown Solid

Uses

A metabolite of Buprenorphine

Definition

ChEBI: Norbuprenorphine is a member of phenanthrenes.

NORBUPRENORPHINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NORBUPRENORPHINE Suppliers

Global 0

78715-23-8, NORBUPRENORPHINERelated Search:

BUPRENORPHINE 2,4-DIMETHYL-4-PHENYLPENTAN-2-OL p-isooctylphenol NORBUPRENORPHINE TRANS-2-PHENYL-1-CYCLOHEXANOL octamylamine 4,4-DIPROPYLHEPTANE 4-tert-Butylcyclohexanol CHEMBRDG-BB 4005901 4-N-PROPYLBICYCLO[2.2.2]OCTAN-1-OL CHEMBRDG-BB 4005902 (-)-NEOMENTHOL 4-METHYL-1-PHENYL-2-PENTANOL (1R,2S)-(-)-TRANS-2-PHENYL-1-CYCLOHEXANOL 4,8-DIMETHYL-1-PHENYLNONANE 2-(1-methylnonyl)phenol

  • (aS,5a,7a)-a-(1,1-Dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-a-methyl-6,14-ethenomorphinan-7-methanol
  • N-De(cyclopropylmethyl)buprenorphine
  • N-Dealkylbuprenorphine
  • N-Desalkylbuprenorphin
  • 6,14-Ethenomorphinan-7-methanol, .alpha.-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-.alpha.-methyl-, (.alpha.S,5.alpha.,7.alpha.)-
  • N-Desalkylbuprenorphine
  • (αS)-α-tert-Butyl-4,5α-epoxy-3-hydroxy-6-methoxy-α-methyl-6β,14-ethanomorphinan-7α-methanol
  • N-Des(cyclopropylmethyl)buprenorphine
  • NORBUPRENORPHINE
  • (αS,5α,7α)-α-(1,1-DiMethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-Methoxy-α-Methyl-6,14-ethenoMorphinan-7-Methanol
  • Norbuprenorphine (1.0 Mg/ML in Methanol)
  • Norbuprenorphine solution
  • Norbuprenorphine (CRM)
  • 6,14-Ethenomorphinan-7-methanol, α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, (αS,5α,7α)-
  • (2S)-2-(4,5α-epoxy-3-hydroxy-6-methoxy-6α,14-ethano-14α-morphinan-7α-yl)-3,3-dimethylbutan-2-ol (norbuprenorphine),
  • Buprenorphine Hydrochloride Impurity B
  • Buprenorphine Impurity B
  • Buprenorphine Hydrochloride EP Impurity B
  • Toremifene Impurity 19
  • 78715-23-8
  • C25H35NO4
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals