NORBUPRENORPHINE

NORBUPRENORPHINE Property

Melting point:

221-224°C

Boiling point:

562.7±50.0 °C(Predicted)

Density 

1.27±0.1 g/cm3(Predicted)

Flash point:

9℃

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

Chloroform (Sparingly), Methanol (Slightly)

pka

9.14±0.60(Predicted)

form 

A neat solid

Safety

Hazard Codes 

F,T

Risk Statements 

11-23/24/25-39/23/24/25

Safety Statements 

16-36/37-45-7

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

NORBUPRENORPHINE Chemical Properties,Usage,Production

Description

Norbuprenorphine (CRM) (Item No. 20127) is a certified reference material categorized as an opioid. It is a major active metabolite of buprenorphine (Item Nos. 14025 | ISO60178). This product is intended for research and forensic applications.

Chemical Properties

Light Brown Solid

Uses

A metabolite of Buprenorphine

Definition

ChEBI: Norbuprenorphine is a member of phenanthrenes.

References

[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] E J CONE. The metabolism and excretion of buprenorphine in humans.[J]. Drug Metabolism and Disposition, 1984, 12 5: 577-581.