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2-hydroxy-4-oxo-pentanedioic acid

Product Name
2-hydroxy-4-oxo-pentanedioic acid
CAS No.
1187-99-1
Chemical Name
2-hydroxy-4-oxo-pentanedioic acid
Synonyms
DL-KHG Li;2-keto-4-hydroxyglutarate;DL-4-Hydroxy-2-ketoglutarate;4-Hydroxy-2-oxoglutaric acid;2-hydroxy-4-oxo-pentanedioic acid;Pentanedioic acid, 2-hydroxy-4-oxo-;4-Hydroxy-2-oxoglutaric acid lithium salt;DL-4-Hydroxy-2-ketoglutarate disodium salt;DL-4-Hydroxy-2-ketoglutarate DilithiuM Salt;DL-4-Hydroxy-2-ketoglutaric acid lithium salt
CBNumber
CB71235556
Molecular Formula
C5H6O6
Formula Weight
162.1
MOL File
1187-99-1.mol
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2-hydroxy-4-oxo-pentanedioic acid Property

Melting point:
>250°C (dec.)
Boiling point:
425.6±35.0 °C(Predicted)
Density 
1.700±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Water
pka
2.34±0.54(Predicted)
form 
Solid
color 
Off-White
BRN 
1780096
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
96599
Product name
DL-4-Hydroxy-2-ketoglutaric acid lithium salt
Purity
≥90.0% (TLC)
Packaging
50mg
Price
$417
Updated
2024/03/01
Sigma-Aldrich
Product number
96599
Product name
DL-4-Hydroxy-2-ketoglutaric acid lithium salt
Purity
≥90.0% (TLC)
Packaging
10mg
Price
$111
Updated
2023/06/20
Sigma-Aldrich
Product number
61076
Product name
DL-4-Hydroxy-2-ketoglutaric acid lithium salt
Purity
analytical standard
Packaging
10mg
Price
$105
Updated
2022/05/15
Sigma-Aldrich
Product number
61076
Product name
DL-4-Hydroxy-2-ketoglutaric acid lithium salt
Purity
analytical standard
Packaging
50mg
Price
$316
Updated
2022/05/15
Usbiological
Product number
279270
Product name
DL-4-Hydroxy-2-ketoglutarate dilithium salt
Packaging
5mg
Price
$355
Updated
2021/12/16
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2-hydroxy-4-oxo-pentanedioic acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A 4-substituted analog of Glutamic acid. This compound is a good enzyme substrate for GOT (glutamic oxalacetic aminotransferase).

Definition

ChEBI: An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively.

Biological Activity

DL-4-Hydroxy-2-ketoglutaric acid (DL-KHG) is an enzyme substrate for GOT (glutamic oxalacetic aminotransferase) and 2-Keto-4-hydroxyglutarate aldolase, which catalyzes the reversible cleavage of 2-keto-4-hydroxyglutarate yielding pyruvate plus glyoxylate; DL-KHG has been used in mass spectrometry for the rapid analysis of negatively charged water-soluble cellular metabolites.

2-hydroxy-4-oxo-pentanedioic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-hydroxy-4-oxo-pentanedioic acid Suppliers

Canada 1 China 9 India 1 South Korea 1 United States 3 Global 15
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Creative Enzymes
Tel
--
Fax
--
Email
info@creative-enzymes.com
Country
United States
ProdList
6057
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

1187-99-1, 2-hydroxy-4-oxo-pentanedioic acidRelated Search:


  • 2-keto-4-hydroxyglutarate
  • DL-4-Hydroxy-2-ketoglutarate
  • 4-Hydroxy-2-oxoglutaric acid lithium salt
  • DL-4-Hydroxy-2-ketoglutaric acid lithium salt
  • DL-KHG Li
  • DL-4-Hydroxy-2-ketoglutarate disodium salt
  • 2-hydroxy-4-oxo-pentanedioic acid
  • 4-Hydroxy-2-oxoglutaric acid
  • DL-4-Hydroxy-2-ketoglutarate DilithiuM Salt
  • Pentanedioic acid, 2-hydroxy-4-oxo-
  • 1187-99-1
  • C5H6O6
  • Aliphatics
  • Enzyme substrates
  • Aliphatics, Enzyme substrates