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N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL

Product Name
N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL
CAS No.
60398-08-5
Chemical Name
N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL
Synonyms
Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH;6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine;N-acetylmuramyl-6-O-stearoyl-L-alanyl-*D-isogluta;Ac-(6-O-stearoyl)-MuraMyl-Ala-D-Isogln-OH, L18-MDP;N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL;N-ACETYLMURAMYL-6-O-STEAROYL-L-ALANYL-D-ISOGLUTAMINE);D-α-Glutamine, N-[N-acetyl-6-O-(1-oxooctadecyl)muramoyl]-L-alanyl-
CBNumber
CB7123702
Molecular Formula
C37H66N4O12
Formula Weight
758.94
MOL File
60398-08-5.mol
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N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL Property

storage temp. 
−20°C
Sequence
Ac-(6-O-stearoyl)-muramyl-Ala-{d-Glu}-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FA107948
Product name
Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH2
Packaging
500ug
Price
$135
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA107948
Product name
Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH2
Packaging
1mg
Price
$236
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA107948
Product name
Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH2
Packaging
2mg
Price
$411
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA107948
Product name
Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH2
Packaging
5mg
Price
$822
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA107948
Product name
Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH2
Packaging
10mg
Price
$1429.6
Updated
2021/12/16
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N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL Chemical Properties,Usage,Production

Uses

L18-MDP is a derivative of muramyl dipeptide, an antibacterial agent. L18-MDP has antibacterial activity and has potential applications in bacterial and fungal infections[1].

in vivo

L18-MDP (100 μg; s.c.; single dose) has anti-infection effect in mice infected with Escherichia coli or Klebsiella pneumoniae[1].
L18-MDP (100 μg or 1000 μg; s.c., i.p., i.v. or p.o.; single dose) increases the survival rate of mice infected with Escherichia coli and improves the pathological tissue of mice infected with Listeria monocytogenes[1].
L18-MDP (100 μg or 200 μg; s.c. or i.p.; once daily for 3 days) increases the survival rate of mice infected with Candida albicans[1].

Animal Model:Mice infected with Escherichia coli, Klebsiella pneumoniae or Listeria monocytogenes[1].
Dosage:100 μg or 1000 μg.
Administration:Subcutaneous injection, intraperitoneal injection, intravenous injection or oral gavage; single dose.
Result:Strengthened the phagocytosis of the microorganisms, weakened the virus activity, increased the survival rate and improved the pathological tissue.
Animal Model:Mice infected with Candida albicans[1].
Dosage:100 μg or 200 μg.
Administration:Subcutaneous injection or intraperitoneal injection; once daily for 3 days.
Result:Strengthened the phagocytosis of the microorganisms, weakened the virus activity, increased the survival rate and improved the pathological tissue.

References

[1] Osada Y, et al. Effect of L18-MDP(Ala), a synthetic derivative of muramyl dipeptide, on nonspecific resistance of mice to microbial infections. Infect Immun. 1982 Jul;37(1):292-300. DOI:10.1128/iai.37.1.292-300.1982

N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL Preparation Products And Raw materials

Raw materials

Preparation Products

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N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL Suppliers

Chemsky (shanghai) International Co.,Ltd
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shchemsky@sina.com
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China
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1-631-485-4226; 16314854226
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info@bocsci.com
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China
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Nanjing TGpeptide Biotechnology Co.,Ltd.
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Nantong QuanYi Biotechnology Co., Ltd
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https://hanhongsci.com/
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60398-08-5, N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYLRelated Search:


  • 6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine
  • N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL
  • N-acetylmuramyl-6-O-stearoyl-L-alanyl-*D-isogluta
  • N-ACETYLMURAMYL-6-O-STEAROYL-L-ALANYL-D-ISOGLUTAMINE)
  • Ac-(6-O-stearoyl)-MuraMyl-Ala-D-Isogln-OH, L18-MDP
  • Ac-(6-O-stearoyl)-muramyl-Ala-D-Glu-NH
  • D-α-Glutamine, N-[N-acetyl-6-O-(1-oxooctadecyl)muramoyl]-L-alanyl-
  • 60398-08-5
  • C37H66N4O12