N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE

Product Name: N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
CAS No.: 259143-19-6
Chemical Name: N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
Synonyms: NALT;N-(α-Linolenoyl) Tyrosine;DEQLZTQITSWABQ-GMOGWPNXSA-N;N-(ALPHA-LINOLEOYL) TYROSINE;N-(.alpha.-Linolenoyl) Tyrosine;N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE;N (α Linolenoyl) Tyrosine,N(αLinolenoyl) Tyrosine;L-Tyrosine, N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-
CBNumber: CB7124693
Molecular Formula: C27H39NO4
Formula Weight: 441.6
MOL File: 259143-19-6.mol

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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Property

storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10032
Product name: N-(α-Linolenoyl) Tyrosine
Purity: ≥98%
Packaging: 5mg
Price: $71
Updated: 2024/03/01

Cayman Chemical

Product number: 10032
Product name: N-(α-Linolenoyl) Tyrosine
Purity: ≥98%
Packaging: 10mg
Price: $133
Updated: 2024/03/01

Cayman Chemical

Product number: 10032
Product name: N-(α-Linolenoyl) Tyrosine
Purity: ≥98%
Packaging: 50mg
Price: $554
Updated: 2024/03/01

Cayman Chemical

Product number: 10032
Product name: N-(α-Linolenoyl) Tyrosine
Purity: ≥98%
Packaging: 100mg
Price: $968
Updated: 2024/03/01

AK Scientific

Product number: 1890AH
Product name: N-(L-Tyrosine)-9Z,12Z,15Z-octadecatrienamide
Packaging: 50mg
Price: $715
Updated: 2021/12/16

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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Chemical Properties,Usage,Production

Description

Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.¹ N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.² In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.²

Definition

ChEBI: N-(alpha-Linolenoyl) Tyrosine is a tyrosine derivative.

References

1. Martin, J.B. Molecular basis of the neurodegenerative disorders N. Engl. J. Med. 340(25),1970-1980(1999).
2. Yehuda, S. Possible anti-Parkinson properties of N-(α-linolenoyl) tyrosine: A new molecule Pharmacol. Biochem. Behav. 72(1-2),7-11(2002).

N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Suppliers

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259143-19-6, N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDERelated Search:

N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE ALPHA-LINOLENOYL ETHANOLAMIDE

N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE

N-(ALPHA-LINOLEOYL) TYROSINE

NALT

N-(α-Linolenoyl) Tyrosine

DEQLZTQITSWABQ-GMOGWPNXSA-N

N-(.alpha.-Linolenoyl) Tyrosine

L-Tyrosine, N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-

N (α Linolenoyl) Tyrosine,N(αLinolenoyl) Tyrosine

259143-19-6