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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE

Product Name
N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
CAS No.
259143-19-6
Chemical Name
N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
Synonyms
NALT;N-(α-Linolenoyl) Tyrosine;DEQLZTQITSWABQ-GMOGWPNXSA-N;N-(ALPHA-LINOLEOYL) TYROSINE;N-(.alpha.-Linolenoyl) Tyrosine;N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE;N (α Linolenoyl) Tyrosine,N(αLinolenoyl) Tyrosine;L-Tyrosine, N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-
CBNumber
CB7124693
Molecular Formula
C27H39NO4
Formula Weight
441.6
MOL File
259143-19-6.mol
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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
10032
Product name
N-(α-Linolenoyl) Tyrosine
Purity
≥98%
Packaging
5mg
Price
$71
Updated
2024/03/01
Cayman Chemical
Product number
10032
Product name
N-(α-Linolenoyl) Tyrosine
Purity
≥98%
Packaging
10mg
Price
$133
Updated
2024/03/01
Cayman Chemical
Product number
10032
Product name
N-(α-Linolenoyl) Tyrosine
Purity
≥98%
Packaging
50mg
Price
$554
Updated
2024/03/01
Cayman Chemical
Product number
10032
Product name
N-(α-Linolenoyl) Tyrosine
Purity
≥98%
Packaging
100mg
Price
$968
Updated
2024/03/01
AK Scientific
Product number
1890AH
Product name
N-(L-Tyrosine)-9Z,12Z,15Z-octadecatrienamide
Packaging
50mg
Price
$715
Updated
2021/12/16
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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Chemical Properties,Usage,Production

Description

Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.1 N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.2 In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.2

Definition

ChEBI: N-(alpha-Linolenoyl) Tyrosine is a tyrosine derivative.

References

1. Martin, J.B. Molecular basis of the neurodegenerative disorders N. Engl. J. Med. 340(25),1970-1980(1999).
2. Yehuda, S. Possible anti-Parkinson properties of N-(α-linolenoyl) tyrosine: A new molecule Pharmacol. Biochem. Behav. 72(1-2),7-11(2002).

N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Suppliers

China 17 Switzerland 1 United States 2 Global 20
AXXORA, LLC
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alexis-ch@alexis-corp.com
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Switzerland
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259143-19-6, N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDERelated Search:

N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE ALPHA-LINOLENOYL ETHANOLAMIDE

  • N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
  • N-(ALPHA-LINOLEOYL) TYROSINE
  • NALT
  • N-(α-Linolenoyl) Tyrosine
  • DEQLZTQITSWABQ-GMOGWPNXSA-N
  • N-(.alpha.-Linolenoyl) Tyrosine
  • L-Tyrosine, N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-
  • N (α Linolenoyl) Tyrosine,N(αLinolenoyl) Tyrosine
  • 259143-19-6