ChemicalBook > CAS DataBase List > Jacobine.

Jacobine.

Product Name
Jacobine.
CAS No.
6870-67-3
Chemical Name
Jacobine.
Synonyms
Jacobine.;NSC-89936;Jacobine-RM;(20S)-15α,20-Epoxy-15,20-dihydro-12-hydroxysenecionan-11,16-dione;(15R,20S)-15,20-Dihydro-15,20-epoxy-12-hydroxysenecionan-11,16-dione;Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2'-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3',5,6-trimethyl-, (2'S,3'S,5R,6R,14aR,14bR)-
CBNumber
CB71248363
Molecular Formula
C18H25NO6
Formula Weight
351.39
MOL File
6870-67-3.mol
More
Less

Jacobine. Property

Melting point:
228°C
Boiling point:
485.2°C (rough estimate)
Density 
1.2737 (rough estimate)
refractive index 
1.5100 (estimate)
pka
12.89±0.60(Predicted)
IARC
3 (Vol. 10, Sup 7) 1987
More
Less

Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
6870-67-3(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
J210395
Product name
Jacobine
Packaging
0.25mg
Price
$160
Updated
2021/12/16
TRC
Product number
J210395
Product name
Jacobine
Packaging
0.5mg
Price
$305
Updated
2021/12/16
TRC
Product number
J210395
Product name
Jacobine
Packaging
1mg
Price
$570
Updated
2021/12/16
Biosynth Carbosynth
Product number
BJ161539
Product name
Jacobine
Packaging
10mg
Price
$900
Updated
2021/12/16
Biosynth Carbosynth
Product number
BJ161539
Product name
Jacobine
Packaging
25mg
Price
$1875
Updated
2021/12/16
More
Less

Jacobine. Chemical Properties,Usage,Production

Description

This alkaloid of the pyrrolizidine group of bases occurs in Senecio cineraria D.C., S. crucifolia and S. Jacobea. It is a laevorotatory base with [α]17D - 46.3° (CHCl 3 ). The alkaloid forms crystalline salts and derivatives, e.g. the hydrochloride, m.p. 220°C; [α]19D - 14.3° (H20); nitrate, m.p. 234°C; methiodide, m.p. 255°C and the picrate, m.p. 180°C which is soluble in H20. The alkaloid contains two active hydrogens and on alkaline hydrolysis yields retronecine and jaconecic acid, ClOH16 0 6, m.p. 182°C; [α]25D + 31.7° containing three O-methyl groups

Uses

Jacobine is a pyrrolizidine alkaloid which has been shown to be an herbivore insect deterrent and may be used in the protection of vegetation. Extracted from Crassocephalum plant of West Africa.

Definition

ChEBI: Jacobine is a pyrrolizine alkaloid.

References

Manske., Can. J. Res., 5,651 (1931)
Hosking, Brandt., New Zealand J. Sci. Tech., 14,638 (1936)
Blackie.,Pharrn. J., 138,102 (1937)
Barger, Blackie., J. Chern. Soc., 584 (1937)
Bradbury, Willis., Austral. J. Chern., 9,258 (1956)
Geissman., ibid, 12,247 (1959)
Bradbury, Masamune., J. Arner. Chern. Soc., 81,5201 (1959)
Masamune., ibid, 82, 5253 (1960)
Freidrichsons, Mathieson, Sutor., Tetrahedron Lett., 35 (1960)

Jacobine. Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Jacobine. Suppliers

China 20 France 1 India 2 United Kingdom 1 United States 4 Global 28
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7787
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55
Biyu Biotechnology (Shanghai) Co., ltd
Tel
021-26018599
Country
China
ProdList
270
Advantage
56
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
8914
Advantage
60
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9449
Advantage
58
Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
Advantage
58
ShangHai Anpel Co, Ltd.
Tel
18017382783 18017382783
Email
shanpel@anpel.com.cn
Country
China
ProdList
9611
Advantage
58

6870-67-3, Jacobine.Related Search:


  • Jacobine.
  • (15R,20S)-15,20-Dihydro-15,20-epoxy-12-hydroxysenecionan-11,16-dione
  • (20S)-15α,20-Epoxy-15,20-dihydro-12-hydroxysenecionan-11,16-dione
  • NSC-89936
  • Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2'-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3',5,6-trimethyl-, (2'S,3'S,5R,6R,14aR,14bR)-
  • Jacobine-RM
  • 6870-67-3
  • C8H25NO6