6-AMINO-5-METHYLNICOTINONITRILE

Product Name: 6-AMINO-5-METHYLNICOTINONITRILE
CAS No.: 183428-91-3
Chemical Name: 6-AMINO-5-METHYLNICOTINONITRILE
Synonyms: BUTTPARK 88\11-38;2-AMINO-5-CYANO-3-PICOLINE;2-Amino-6-chloroquinazoline;6-AMINO-5-METHYLNICOTINONITRILE;5-amino-6-methylnicotinonitrile;2-Amino-3-methyl-5-cyanopyridine;2-Amino-5-cyano-3-methylpyridine;5-Cyano-2-amino-3-methylpyridine;6-Amino-5-methylnicotinonitrile 98%;6-amino-5-methylpyridine-3-carbonitrile
CBNumber: CB7127104
Molecular Formula: C7H7N3
Formula Weight: 133.15
MOL File: 183428-91-3.mol

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6-AMINO-5-METHYLNICOTINONITRILE Property

Boiling point:: 321.2±42.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.79±0.49(Predicted)
Appearance: Light yellow to green yellow Solid
InChI: InChI=1S/C7H7N3/c1-5-2-6(3-8)4-10-7(5)9/h2,4H,1H3,(H2,9,10)
InChIKey: SLOISJVQLUVVSD-UHFFFAOYSA-N
SMILES: C1=NC(N)=C(C)C=C1C#N

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Safety

Risk Statements: 41
Safety Statements: 26-39-24/25
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A898583
Product name: 6-Amino-5-methylnicotinonitrile
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA42031
Product name: 2-Amino-5-cyano-3-picoline
Packaging: 500mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: W3974
Product name: 2-Amino-5-cyano-3-picoline
Packaging: 10g
Price: $611
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA42031
Product name: 2-Amino-5-cyano-3-picoline
Packaging: 10g
Price: $650
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK169519
Product name: 6-Amino-5-methylpyridine-3-carbonitrile
Purity: 97%
Packaging: 1g
Price: $335
Updated: 2021/12/16

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6-AMINO-5-METHYLNICOTINONITRILE Chemical Properties,Usage,Production

Chemical Properties

Yellow solid

Synthesis

557-21-1

3430-21-5

183428-91-3

Step I: Synthesis of 2-amino-3-methyl-5-cyanopyridine 1. To a mixture of DMF and water (100:2, v/v, total 102 mL), 5-bromo-3-methylpyridin-2-amine (10 g, 53.47 mmol), zinc cyanide (3.77 g, 32.1 mmol), and 1,1'-bis(diphenylphosphino)ferrocene (3.56 g, 6.4 mmol) were added sequentially. 2. The mixture was degassed for 20 min. 3. tris(dibenzylideneacetone)dipalladium(0) (2.45 g, 2.67 mmol) was added and the reaction mixture was heated and stirred at 120 °C for 16 hours. 4. Upon completion of the reaction, the mixture was cooled to room temperature. 5. A mixture of saturated ammonium chloride solution, ammonium hydroxide and water (4:1:4 by volume, totaling 100 mL) was added. 6. cooled the formed slurry to 0 °C, added again a mixture of saturated ammonium chloride solution, ammonium hydroxide and water in the same ratio (100 mL) and stirred for 1 hour. 7. The solid product was collected by filtration through a Büchner funnel and dried under high vacuum to afford 2-amino-3-methyl-5-cyanopyridine 6.0 g (81% yield) as a tan solid. MS (ES) m/z 134.1 (M + 1).

References

[1] Patent: WO2013/42139, 2013, A1. Location in patent: Page/Page column 83
[2] Patent: US2015/65464, 2015, A1. Location in patent: Paragraph 0368-0369
[3] European Journal of Medicinal Chemistry, 2014, vol. 84, p. 404 - 416

6-AMINO-5-METHYLNICOTINONITRILE Preparation Products And Raw materials

Raw materials

Copper(I) Cyanide N,N-Dimethylformamide Hydrogen peroxide 2-Amino-3-picoline Hydrogen bromide Ethyl acetate PETROLEUM ETHER

Preparation Products

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6-AMINO-5-METHYLNICOTINONITRILE Suppliers

China 88 Europe 1 Germany 2 India 1 United Kingdom 3 United States 17 Global 112

Shanghai Huifu Bio-pharmaceutical Technology Co. , Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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View Lastest Price from 6-AMINO-5-METHYLNICOTINONITRILE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 6-AMINO-5-METHYLNICOTINONITRILE 183428-91-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-04-30

Career Henan Chemical Co

Product: 6-AMINO-5-METHYLNICOTINONITRILE 183428-91-3
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

183428-91-3, 6-AMINO-5-METHYLNICOTINONITRILERelated Search:

1-(Tetrahydro-pyran-2-yl)-1H-indazol-6-ylamine 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID 6-AMINO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 6-AMINO-4-CHLORO-1H-INDAZOLE 2-AMINO-6-CHLORO-3,5-DICYANOPYRIDINE 6-AMINO-2-METHYLNICOTINONITRILE 2,6-bis[(3-methoxypropyl)amino]-4-methylnicotinonitrile Acetonitrile 2-Amino-6-chloro-3,5-dicyano-4-methylpyridine 2,6-bis[(2-hydroxyethyl)amino]-4-methylnicotinonitrile 2-AMINO-5-METHYLNICOTINONITRILE N'-(6-[4-(6-CHLORO-2-PYRIDINYL)PIPERAZINO]-3,5-DICYANO-2-PYRIDINYL)-N,N-DIMETHYLIMINOFORMAMIDE 2-amino-4-methylnicotinonitrile 5-[[2-chloro-4-(phenylazo)phenyl]azo]-2,6-bis[(3-methoxypropyl)amino]-4-methylnicotinonitrile 5-ACETYL-2-[BENZYL(METHYL)AMINO]-6-METHYLNICOTINONITRILE N'-(6-(4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINO)-3,5-DICYANO-2-PYRIDINYL)-N,N-DIMETHYLIMINOFORMAMIDE 2-(4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINO)-6-(1H-PYRROL-1-YL)-3,5-PYRIDINEDICARBONITRILE 2-AMINO-6-ETHOXY-4-PHENYL-3,5-PYRIDINEDICARBONITRILE

6-AMINO-5-METHYLNICOTINONITRILE

BUTTPARK 88\11-38

5-Cyano-2-amino-3-methylpyridine

3-Pyridinecarbonitrile,6-amino-5-methyl

2-AMINO-5-CYANO-3-PICOLINE

6-amino-5-methylpyridine-3-carbonitrile

3-Pyridinecarbonitrile,6-amino-5-methyl-(9CI)

6-Amino-5-methylpyridine-3-carbonitrile ,97%

2-Amino-5-cyano-3-methylpyridine

2-Amino-3-methyl-5-cyanopyridine

2-Amino-6-chloroquinazoline

5-amino-6-methylnicotinonitrile

5-Amino-6-methyl-pyridine-3-carbonitrile

6-amino-5-methyl-3-pyridinecarbonitrile

6-Amino-5-methylnicotinonitrile 98%

6-AMINO-5-METHYLNICOTINONITRILE ISO 9001：2015 REACH

183428-91-3

PYRIDINE