6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID

Product Name: 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID
CAS No.: 73907-95-6
Chemical Name: 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID
Synonyms: TIMTEC-BB SBB002550;7-Carboxy-1H-indazole-6-amine;6-Amino-7-carboxy-1H-indazole;6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID;1H-Indazole-7-carboxylic acid, 6-aMino-
CBNumber: CB8296412
Molecular Formula: C8H7N3O2
Formula Weight: 177.16
MOL File: Mol file

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6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID Property

Melting point:: 177 °C (decomp)
Boiling point:: 501.6±35.0 °C(Predicted)
Density: 1.611
storage temp.: Sealed in dry,Room Temperature
form: Solid
pka: 16.17±0.40(Predicted)
Appearance: Yellow to brown Solid

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: A637108
Product name: 6-Amino-1H-indazole-7-carboxylicacid
Packaging: 500mg
Price: $265
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA143601
Product name: 6-Amino-1H-indazole-7-carboxylic acid
Packaging: 1g
Price: $365
Updated: 2021/12/16

Matrix Scientific

Product number: 119641
Product name: 6-Amino-1H-indazole-7-carboxylic acid
Purity: 95+%
Packaging: 1g
Price: $630
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA143601
Product name: 6-Amino-1H-indazole-7-carboxylic acid
Packaging: 2g
Price: $634
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA143601
Product name: 6-Amino-1H-indazole-7-carboxylic acid
Packaging: 100mg
Price: $61
Updated: 2021/12/16

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6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

73907-94-5

73907-95-6

Pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione (Formula 7, the product of Example II, 9.4 g, 50 mmol) was used as a raw material, which was dissolved in 10% aqueous sodium hydroxide solution (100 mL). Subsequently, 10% aqueous hydrogen peroxide solution (17 mL, 50 mmol) was slowly added at 100 °C. The reaction mixture was kept at 100°C for 10 minutes until the release of carbon dioxide gas stopped. Next, the pH of the reaction solution was adjusted with concentrated hydrochloric acid to 4.0-5.5. The resulting 6-amino-1H-indazole-7-carboxylic acid (formula 8) was collected by filtration and washed with cold water, and finally dried under vacuum in the presence of CaCl2 to give 7.71 g of the product in brown powder form in 87% yield with a melting point of 205 °C (decomposition started at 177 °C). The infrared spectrum (KBr) of the product showed characteristic absorption peaks: 1580, 1630, 1660 cm-1 (corresponding to aromatic ring and carbonyl carboxylic acid, respectively). The NMR hydrogen spectrum (100 MHz, DMSO-d6) data were as follows: δ 6.70 (d, 1H, J=9Hz, H-4), ca. 6.80-9.00 (D2O-exchangeable broad peak, 2H, NH2), 7.66 (d, 1H, J=9Hz, H-5), and 7.93 (s, 1H, H-3). The mass spectrum (70 eV) showed molecular ion peaks m/e 177 (100%, M+) and m/e 159 (86%, M+-H2O). Samples recrystallized from methanol failed to yield satisfactory data by elemental analysis.

References

[1] Tetrahedron Letters, 1980, vol. 21, # 32, p. 3029 - 3032
[2] Journal of Organic Chemistry, 1980, vol. 45, # 15, p. 3072 - 3077
[3] Heterocycles, 1981, vol. 15, # 2, p. 1053 - 1059
[4] Patent: US4223143, 1980, A
[5] Patent: WO2007/93402, 2007, A1. Location in patent: Page/Page column 42

6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID Suppliers

China 60 Finland 1 France 2 India 1 Russia 1 United Kingdom 2 United States 13 Global 80

JinYan Chemicals(ShangHai) Co.,Ltd.

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View Lastest Price from 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID 73907-95-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-18

Career Henan Chemical Co

Product: 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID 73907-95-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%Min
Supply Ability: 10 tons
Release date: 2019-09-10

73907-95-6, 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACIDRelated Search:

6-AMINO-4-CHLORO-1H-INDAZOLE 6-AMINO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 1-(Tetrahydro-pyran-2-yl)-1H-indazol-6-ylamine 6-AMINO-5-METHYLNICOTINONITRILE 1H-indazole-7-carboxylic acid

6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID

6-Amino-7-carboxy-1H-indazole

7-Carboxy-1H-indazole-6-amine

1H-Indazole-7-carboxylic acid, 6-aMino-

TIMTEC-BB SBB002550

73907-95-6

73907956

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