N-ACETYL-L-CYSTEINE METHYL ESTER

Product Name: N-ACETYL-L-CYSTEINE METHYL ESTER
CAS No.: 32381-28-5
Chemical Name: N-ACETYL-L-CYSTEINE METHYL ESTER
Synonyms: DACDM;NSC136019;NSC 136019;NSC-136019;AC-L-CYS-OME;(AC-CYS-OME)2;(Ac-L-Cys-OMe)2;Acetylcysteine Impurity 52;N-Acetylcysteine methyl ester;(Ac-Cys-OMe)2 (Disulfide bond)
CBNumber: CB7128631
Molecular Formula: C12H20N2O6S2
Formula Weight: 352.43
MOL File: 32381-28-5.mol

More

Less

N-ACETYL-L-CYSTEINE METHYL ESTER Property

Melting point:: 77-81 °C
Boiling point:: 584.5±50.0 °C(Predicted)
Density: 1.285±0.06 g/cm3(Predicted)
storage temp.: -15°C
solubility: DMSO: Soluble: = 10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
pka: 13.89±0.46(Predicted)

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-23

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: A192375
Product name: (Ac-Cys-OMe)2(DisulfideBond)
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: A192375
Product name: (Ac-Cys-OMe)2(DisulfideBond)
Packaging: 500mg
Price: $130
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0010589
Product name: (AC-CYS-OME)-2-DISULFIDE BOND
Purity: 95.00%
Packaging: 250MG
Price: $162.75
Updated: 2021/12/16

AK Scientific

Product number: 4328AH
Product name: (Ac-Cys-Ome)2(disulfidebond)
Packaging: 1g
Price: $185
Updated: 2021/12/16

Chem-Impex

Product number: 04348
Product name: Acetyl-L-cystinebis-methylester[Disulfidebond],98%(Assay)
Purity: 98%(Assay)
Packaging: 5G
Price: $324.8
Updated: 2021/12/16

More

Less

N-ACETYL-L-CYSTEINE METHYL ESTER Chemical Properties,Usage,Production

Description

Dimethyl diacetyl cystinate is a derivative of the oxidized dimeric form of cysteine L-cystine (Item No. 31727).1 It inhibits UVB radiation-induced NF-κB nuclear translocation in and IL-1α secretion from HaCaT cells when used at concentrations of 50 or 100 µM. Dimethyl diacetyl cystinate (10 µg/ml) decreases proliferation and IFN-γ and IL-2 secretion in a co-culture of lymphocytes isolated from BALB/c mice and irradiated splenocytes isolated from C57BL/10J mice.2 Subconjunctival administration of dimethyl diacetyl cystinate (8 µg/animal) reduces corneal glutathione (GSH) levels and increases corneal allograft survival in mice.WARNING This product is not for human or veterinary use.

Chemical Properties

White powder

References

[1] MANABU KITAZAWA. Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-κB activation[J]. FEBS Letters, 2002, 526 1-3: 106-110. DOI: 10.1016/s0014-5793(02)03152-6
[2] JUN YAMADA. Major histocompatibility complex semi-matching improves murine corneal allograft survival under oxidative macrophage dominancy.[J]. Transplantation, 2007, 84 7: 899-907. DOI: 10.1097/01.tp.0000284731.22247.a3

N-ACETYL-L-CYSTEINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-ACETYL-L-CYSTEINE METHYL ESTER Suppliers

China 34 Germany 2 India 4 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 6 Global 49

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Shanghai Hekang Biotechnology Co., Ltd.

Tel: 18939837085
Fax: 2880152141(QQ)
Email: youchemicals@gmail.com
Country: China
ProdList: 1839
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Kanghua (Shanghai) New Drug Development Co., Ltd.

Tel: 021-61263370 18901917034
Email: xingli@glbiochem.com
Country: China
ProdList: 5637
Advantage: 58

Shanghai Jifeng Biotechnology Co., Ltd.

Tel: 021-61263377 15023907684
Fax: 021-61263399
Email: 15800684150@163.com
Country: China
ProdList: 8131
Advantage: 58

GL Biochem (Shanghai) Ltd.

Tel: +86-021-61263370 +86-18901917034
Country: CHINA
ProdList: 3904
Advantage: 58

32381-28-5, N-ACETYL-L-CYSTEINE METHYL ESTERRelated Search:

AC-CYS(FARNESYL)-OME N-ACETYL-L-CYSTEINE METHYL ESTER (DES-GLY)-GLUTATHIONE-MONOETHYL ESTER (REDUCED) N-(3-nitratopivaloyl)cysteine ethyl ester N-ACETYL-S-BENZYL-L-CYSTEINE METHYL ESTER ALANINE, N-ACETYL-3-((2-CHLORO-2-METHYLPROPYL)THIO)-, METHYL ESTER, L- N-TRIFLUOROACETYL-L-CYSTEINE METHYL ESTER N,N'-BIS(TRIFLUOROACETYL) L-CYSTINE DIMETHYL ESTER N,S-DIACETYL-L-CYSTEINE METHYL ESTER N-ACETYL-L-CYSTEINE METHYL ESTER BOC-CYSTINE-ALA-ALA-GLY-VAL-CYSTEINE-OME BOC-CYSTINE-PHE-CYSTEINE-OME FA-CYS(FARNESYL)-OME CBZ-GLY-S-BENZYL-L-CYS-S-BENZYL-L-CYS ETHYL ESTER BOC-CYSTINE-CYSTEINE-OME AC-CYS-HIS-SER-GLY-TYR-VAL-GLY-VAL-ARG-CYS-OME N-TRIFLUOROACETYL-L-G-GLUTAMYL-L-CYSTEINE DIMETHYL ESTER, (2-2') DISULPHIDE BOC-CYSTINE-GLY-GLY-GLY-GLY-CYSTEINE-OME

N-ACETYL-L-CYSTEINE METHYL ESTER

(AC-CYS-OME)2

ACETYL-L-CYSTINE DIMETHYL ESTER

AC-L-CYS-OME

3,3'-Dithiobis[(R)-2-(acetylamino)propanoic acid methyl] ester

DACDM

N,N'-Diacetylcystine dimethyl ester

N,N'-Diacetyl-L-cystine dimethyl ester

(2R)-2-(Acetylamino)-3-mercaptopropionic acid methyl ester

N-Acetylcysteine methyl ester

(Ac-L-Cys-OMe)2

Acetyl-L-cystine bis-methyl ester[Disulfide bond]≥ 99% (TLC)

(Ac-Cys-OMe)2 (Disulfide bond)

L-Cystine, N,N'-diacetyl-, 1,1'-dimethyl ester

Acetyl-L-cystine bis-methyl ester[Disulfide bond]

(2R,2'R)-Dimethyl 3,3'-disulfanediylbis(2-acetamidopropanoate)

NSC 136019

NSC136019

NSC-136019

Dimethyl 3,3'-disulfanediyl(2r,2'r)-bis(2-acetamidopropanoate)

Acetylcysteine Impurity 52

Dimethyl (2R,2'R)-3,3'-Disulfanediylbis(2-acetamidopropanoate)

32381-28-5

C12H20N2O6S2

Cysteine/Cystine

Specialty Synthesis

Peptide Synthesis

Amino Acid Derivatives