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N-ACETYL-L-CYSTEINE METHYL ESTER

Product Name
N-ACETYL-L-CYSTEINE METHYL ESTER
CAS No.
32381-28-5
Chemical Name
N-ACETYL-L-CYSTEINE METHYL ESTER
Synonyms
DACDM;NSC136019;NSC 136019;NSC-136019;AC-L-CYS-OME;(AC-CYS-OME)2;(Ac-L-Cys-OMe)2;Acetylcysteine Impurity 52;N-Acetylcysteine methyl ester;(Ac-Cys-OMe)2 (Disulfide bond)
CBNumber
CB7128631
Molecular Formula
C12H20N2O6S2
Formula Weight
352.43
MOL File
32381-28-5.mol
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N-ACETYL-L-CYSTEINE METHYL ESTER Property

Melting point:
77-81 °C
Boiling point:
584.5±50.0 °C(Predicted)
Density 
1.285±0.06 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
DMSO: Soluble: = 10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
pka
13.89±0.46(Predicted)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
10-23
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A192375
Product name
(Ac-Cys-OMe)2(DisulfideBond)
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
A192375
Product name
(Ac-Cys-OMe)2(DisulfideBond)
Packaging
500mg
Price
$130
Updated
2021/12/16
Chem-Impex
Product number
04348
Product name
Acetyl-L-cystine bis-methyl ester[Disulfide bond]
Purity
≥ 98% (Assay)
Packaging
250MG
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA48133
Product name
Acetyl-L-cystine bis-methyl ester
Packaging
500mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA48133
Product name
Acetyl-L-cystine bis-methyl ester
Packaging
1g
Price
$101.2
Updated
2021/12/16
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N-ACETYL-L-CYSTEINE METHYL ESTER Chemical Properties,Usage,Production

Description

Dimethyl diacetyl cystinate is a derivative of the oxidized dimeric form of cysteine L-cystine (Item No. 31727).1 It inhibits UVB radiation-induced NF-κB nuclear translocation in and IL-1α secretion from HaCaT cells when used at concentrations of 50 or 100 µM. Dimethyl diacetyl cystinate (10 µg/ml) decreases proliferation and IFN-γ and IL-2 secretion in a co-culture of lymphocytes isolated from BALB/c mice and irradiated splenocytes isolated from C57BL/10J mice.2 Subconjunctival administration of dimethyl diacetyl cystinate (8 µg/animal) reduces corneal glutathione (GSH) levels and increases corneal allograft survival in mice.WARNING This product is not for human or veterinary use.

Chemical Properties

White powder

References

[1] MANABU KITAZAWA. Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-κB activation[J]. FEBS Letters, 2002, 526 1-3: 106-110. DOI: 10.1016/s0014-5793(02)03152-6
[2] JUN YAMADA. Major histocompatibility complex semi-matching improves murine corneal allograft survival under oxidative macrophage dominancy.[J]. Transplantation, 2007, 84 7: 899-907. DOI: 10.1097/01.tp.0000284731.22247.a3

N-ACETYL-L-CYSTEINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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N-ACETYL-L-CYSTEINE METHYL ESTER Suppliers

China 34 Germany 2 India 4 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 6 Global 49
SIGMA-RBI
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Switzerland
ProdList
6896
Advantage
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32381-28-5, N-ACETYL-L-CYSTEINE METHYL ESTERRelated Search:

AC-CYS(FARNESYL)-OME N-ACETYL-L-CYSTEINE METHYL ESTER (DES-GLY)-GLUTATHIONE-MONOETHYL ESTER (REDUCED) N-(3-nitratopivaloyl)cysteine ethyl ester N-ACETYL-S-BENZYL-L-CYSTEINE METHYL ESTER ALANINE, N-ACETYL-3-((2-CHLORO-2-METHYLPROPYL)THIO)-, METHYL ESTER, L- N-TRIFLUOROACETYL-L-CYSTEINE METHYL ESTER N,N'-BIS(TRIFLUOROACETYL) L-CYSTINE DIMETHYL ESTER N,S-DIACETYL-L-CYSTEINE METHYL ESTER N-ACETYL-L-CYSTEINE METHYL ESTER BOC-CYSTINE-ALA-ALA-GLY-VAL-CYSTEINE-OME BOC-CYSTINE-PHE-CYSTEINE-OME FA-CYS(FARNESYL)-OME CBZ-GLY-S-BENZYL-L-CYS-S-BENZYL-L-CYS ETHYL ESTER BOC-CYSTINE-CYSTEINE-OME AC-CYS-HIS-SER-GLY-TYR-VAL-GLY-VAL-ARG-CYS-OME N-TRIFLUOROACETYL-L-G-GLUTAMYL-L-CYSTEINE DIMETHYL ESTER, (2-2') DISULPHIDE BOC-CYSTINE-GLY-GLY-GLY-GLY-CYSTEINE-OME

  • N-ACETYL-L-CYSTEINE METHYL ESTER
  • (AC-CYS-OME)2
  • ACETYL-L-CYSTINE DIMETHYL ESTER
  • AC-L-CYS-OME
  • 3,3'-Dithiobis[(R)-2-(acetylamino)propanoic acid methyl] ester
  • DACDM
  • N,N'-Diacetylcystine dimethyl ester
  • N,N'-Diacetyl-L-cystine dimethyl ester
  • (2R)-2-(Acetylamino)-3-mercaptopropionic acid methyl ester
  • N-Acetylcysteine methyl ester
  • (Ac-L-Cys-OMe)2
  • Acetyl-L-cystine bis-methyl ester[Disulfide bond]≥ 99% (TLC)
  • (Ac-Cys-OMe)2 (Disulfide bond)
  • L-Cystine, N,N'-diacetyl-, 1,1'-dimethyl ester
  • Acetyl-L-cystine bis-methyl ester[Disulfide bond]
  • (2R,2'R)-Dimethyl 3,3'-disulfanediylbis(2-acetamidopropanoate)
  • NSC 136019
  • NSC136019
  • NSC-136019
  • Dimethyl 3,3'-disulfanediyl(2r,2'r)-bis(2-acetamidopropanoate)
  • Acetylcysteine Impurity 52
  • Dimethyl (2R,2'R)-3,3'-Disulfanediylbis(2-acetamidopropanoate)
  • 32381-28-5
  • C12H20N2O6S2
  • Cysteine/Cystine
  • Specialty Synthesis
  • Peptide Synthesis
  • Amino Acid Derivatives