Identification Description Regulatory Status Usage Natural occurrence Production
ChemicalBook > CAS DataBase List > 2-Acetylpyridine

2-Acetylpyridine

Identification Description Regulatory Status Usage Natural occurrence Production
Product Name
2-Acetylpyridine
CAS No.
1122-62-9
Chemical Name
2-Acetylpyridine
Synonyms
Ethanone, 1-(2-pyridinyl)-;1-(2-pyridinyl)-Ethanone;Acetyl pyridine;1-PYRIDIN-2-YL-ETHANONE;2-ACETYLPYRIDINE, STANDARD FOR GC;FEMA 3251;2-ACETOPYRIDINE;2-Acetalpyridine;2-Acetylpyradine;2-Acttylpyridine
CBNumber
CB7131206
Molecular Formula
C7H7NO
Formula Weight
121.14
MOL File
1122-62-9.mol
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2-Acetylpyridine Property

Melting point:
8-10 °C
Boiling point:
188-189 °C (lit.)
Density 
1.08 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.521(lit.)
FEMA 
3251 | 2-ACETYLPYRIDINE
Flash point:
164 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
170g/l
form 
Liquid
pka
pK1: 2.643(+1) (25°C)
color 
Clear colorless to slightly brown
PH
7 (100g/l, H2O, 20℃)
Odor
roasted odor
Odor Type
popcorn
Water Solubility 
Soluble in water (18.2 g/100g @ 25C). Soluble in and acetate. Slightly soluble in carbon tetrachloride.
JECFA Number
1309
BRN 
107759
LogP
0.85
CAS DataBase Reference
1122-62-9(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2-pyridinyl)-(1122-62-9)
EPA Substance Registry System
2-Acetylpyridine (1122-62-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-38
Safety Statements 
26-36-37
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
OB5310000
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W325104
Product name
2-Acetylpyridine
Purity
≥99%, FG
Packaging
100g
Price
$76.5
Updated
2024/03/01
Sigma-Aldrich
Product number
W325104
Product name
2-Acetylpyridine
Purity
≥99%, FG
Packaging
1kg
Price
$259
Updated
2024/03/01
Sigma-Aldrich
Product number
W325104
Product name
2-Acetylpyridine
Purity
≥99%, FG
Packaging
5kg
Price
$1040
Updated
2024/03/01
Sigma-Aldrich
Product number
W325104
Product name
2-Acetylpyridine
Purity
≥99%, FG
Packaging
25kg
Price
$3260
Updated
2024/03/01
Sigma-Aldrich
Product number
1009479
Product name
2-Acetylpyridine
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
1g
Price
$188
Updated
2024/03/01
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2-Acetylpyridine Chemical Properties,Usage,Production

Identification

CAS.No.: 
1122-62-9 
FL.No.: 
14.038
FEMA.No.: 
3251
NAS.No.: 
3251
CoE.No.: 
2315
EINECS.No.: 
214-355-6 
JECFA.No.: 
1309
 
 

Description

A colorless liquid with tobacco-like aroma.

Regulatory Status

CoE: Used provisionally. Food: 10 ppm
FDA: n/a
FDA (other): n/a
JECFA: ADI: Acceptable. No safety concern at current levels of intake when used as a flavoring agent (2004).

Usage

Reported uses (ppm): (FEMA, 1994)

Food Category 
Usual 
Max  
Baked goods 
5
5
Breakfast cereals 
3
3
Cheese 
3
3
Gravies 
3
3
Meat products 
3
3
Milk products 
3
3
Other grains 
3
3
Soft candy 
3
3
Soups 
3
3

Natural occurrence

Reported found in wheaten bread, other types of breads, boiled and cooked beef, grilled and roasted beef, lamb (roasted), lamb and mutton liver, beer, several types of brandy, cocoa, black tea, roasted filbert (Corylus avellano), roasted peanut (Arachis hypogea), heated beans, Bantu beer, coriander seed (Coriandrum sativum L.) and other natural sources.

Production

It is obtained by bromination of ethylpyrazine, followed by oxidization to obtain it.

Description

2-Acetylpyridine: a widely used food additive
2-Acetylpyridine, also named 1-(2-pyridinyl)ethanone or methyl 2-pyridyl ketone, is a "popcorn"-like compound and often used as the food additive and flavouring substance in tobacco, ice cream, milk, cooked rice and other food products. Generally, 2-acetylpyridine exists in a colorless to yellowish liquid and can be naturally found in rice, hazelnuts, Yahonkaoluo leaves and cocoa. Studies have also suggested that it can be used as an intermediate to synthesize a series of chemical compounds with antiviral activity. For example, Abid et al. prepared the various oxime ether derivatives of 2-acetylpyridine and evaluated their antiamoebic activities against the HM1:IMSS strain of E. histolytica[1].

Chemical Properties

clear colorless to slightly brown liquid

Chemical Properties

A colorless liquid with tobacco-like aroma

Occurrence

Reported found in wheaten bread, other types of breads, boiled and cooked beef, grilled and roasted beef, lamb (roasted), lamb and mutton liver, beer, several types of brandy, cocoa, black tea, roasted filbert (Corylus avellano), roasted peanut (Arachis hypogea), heated beans, Bantu beer, coriander seed (Coriandrum sativum L.) and other natural sources.

Uses

2-Acetylpyridine used as flavoring agent. It is also used in application for food additive.

Uses

2-Acetylpyridine is an aroma and flavour compound present in foods.

Definition

ChEBI: 2-Acetylpyridine is an aromatic ketone.

Preparation

From ethyl picolinate

Aroma threshold values

Detection: 19 ppb

Taste threshold values

Taste characteristics at 10 ppm: cornmeal with nutty, bready nuance

General Description

2-Acetylpyridine is a volatile flavor compound found in rye bread crust and roasted sesame. It has also been identified as a key contributor to the “scented rice”-like aroma in Yahonkaoluo leaves and Xiangjing-8618 rice.

References

[1] Cuiping Zhai, Xuejun Liu, Fenghua Cui . “A combined experimental and theoretical study on vibrational spectra of 2-acetylpyridine.” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 134 (2015): Pages 90-95
[2] Camila V. Garcia . “Cobalt(III) complexes with 2-acetylpyridine-derived Schiff bases: Studies investigating ligand release upon reduction.” Polyhedron 124 (2017): Pages 86-95.

2-Acetylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Acetylpyridine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-Acetylpyridine 1122-62-9
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Week
Release date
2024-05-06
Hebei Weibang Biotechnology Co., Ltd
Product
2-Acetylpyridine 1122-62-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-04
Shandong Deshang Chemical Co., Ltd.
Product
2-Acetylpyridine 1122-62-9
Price
US $9.30-6.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 tons
Release date
2024-07-09

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