MEN 935
- Product Name
- MEN 935
- CAS No.
- 75708-29-1
- Chemical Name
- MEN 935
- Synonyms
- MEN 935;3-[3-[(2-hydroxy-3-naphthalen-1-yloxypropyl)amino]-3-methylbutyl]-1H-benzimidazol-2-one
- CBNumber
- CB71326382
- Molecular Formula
- C25H29N3O3.ClH.H2O
- Formula Weight
- 473.998
- MOL File
- 75708-29-1.mol
N-Bromosuccinimide Price
- Product number
- A291575
- Product name
- Adimolol
- Packaging
- 10mg
- Price
- $570
- Updated
- 2021/12/16
- Product number
- API0016916
- Product name
- ADIMOLOL HYDROCHLORIDE HYDRATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.12
- Updated
- 2021/12/16
MEN 935 Chemical Properties,Usage,Production
Originator
Adimolol hydrochloride ,ZYF Pharm Chemical
Uses
Adimolol is an antihypertensive agent and a β-adrenoceptor blocker.
Manufacturing Process
A mixture consisting of 3 g of 1-(3-amino-3,3-dimethyl-n-propyl)
benzimidazolidinone-2, 3.3 g of 1-[naphthyl-(1)-oxyl]propylene-(2,3)-epoxide
and 12 ml of 98% ethanol were refluxed for three hours. Thereafter, the
ethanol was distilled off, the residue was taken up in some methanol, and the
solution was acidified with 1 N hydrochloric acid and then extracted with ethyl
acetate. The ethyl acetate was distilled out of the extract solution, and ether
and some water were added to the residue, whereupon a crystalline substance
separated out. The product was recrystallized from ethanol, yielding 60% of
theory of ()-1-(3-((2-hydroxy-3-(1-naphthyloxy)propyl)amino)-3-
methylbutyl)-2-benzimidazolinone, which had a melting point of 161°C.
In practice it is usually used as hydrochloride.
Therapeutic Function
Alpa- and Beta-adrenergic blocker
MEN 935 Preparation Products And Raw materials
Raw materials
Preparation Products
MEN 935 Suppliers
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