alinastine
- Product Name
- alinastine
- CAS No.
- 154541-72-7
- Chemical Name
- alinastine
- Synonyms
- alinastine;1H-Benzimidazole, 2-[1-[2-[4-(1,1-dimethylethyl)phenyl]ethyl]-4-piperidinyl]-1-(2-ethoxyethyl)-
- CBNumber
- CB71332721
- Molecular Formula
- C28H39N3O
- Formula Weight
- 433.636
- MOL File
- 154541-72-7.mol
alinastine Property
- Boiling point:
- 574.2±50.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3(Predicted)
- pka
- 8.78±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- API0010631
- Product name
- ALINASTINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.71
- Updated
- 2021/12/16
alinastine Chemical Properties,Usage,Production
Originator
Alinastine ,Fabrica Espanola de Productos Quimicos y Farmaceuticos
Manufacturing Process
1.5 g of a sodium hydride suspension in oil are added to another suspension of 10.83 g of 2-[1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidin-4-yl]-1Hbenzimidazole in 150 ml of dimethylformamide and the mixture is stirred for 1 h at room temperature, then a solution of 2-(2-ethoxyethyl)tosylate in dimethylformamide are slowly added. The mixture is heated at 60°C for 16 h, poured onto water and extracted with ether. The extracts are washed with water, dried over anhydrous sodium sulfate and concentrated. The obtained oil is purified by column chromatography yielding 6.0 g of 1-(2-ethoxyethyl)-2- [1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidine-4-yl]-1H-benzimidazole, melting point 138°-140°C.
Therapeutic Function
Antihistaminic, Antiallergic
alinastine Preparation Products And Raw materials
Raw materials
Preparation Products
alinastine Suppliers
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