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cis-1,4-Cyclohexanedicarboxybic acid

Product Name
cis-1,4-Cyclohexanedicarboxybic acid
CAS No.
619-81-8
Chemical Name
cis-1,4-Cyclohexanedicarboxybic acid
Synonyms
CIS-1,4-CYCLOHEXANEDICARBOXYLIC ACID;cis-Cyclohexane-1,4-dicarboxylic acid;Cyclohexanedicarboxylicacid;CIS-HEXAHYDROTEREPHTHALIC ACID;Cis-1,4-CyclohexanedicarboxylicAci;CIS-1,4-CYCLOHEXANEDICARBOXYBIC ACID;1,4-Cyclohexanedicarboxylic acid, cis-;cis-1,4-Cyclohexanedicarboxylic Acid >rac-(1s,4s)-cyclohexane-1,4-dicarboxylic acid
CBNumber
CB7135648
Molecular Formula
C8H12O4
Formula Weight
172.18
MOL File
619-81-8.mol
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cis-1,4-Cyclohexanedicarboxybic acid Property

Melting point:
168 °C
Boiling point:
384.1±35.0 °C(Predicted)
Density 
1.3200
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Ethanol,Ether,Chloroform,Methanol
form 
powder to crystal
pka
4.51±0.25(Predicted)
color 
White to Almost white
CAS DataBase Reference
619-81-8(CAS DataBase Reference)
NIST Chemistry Reference
cis-Hexahydroterephthalic acid(619-81-8)
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Safety

HS Code 
29172090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C0789
Product name
cis-1,4-Cyclohexanedicarboxylic Acid
Purity
>90.0%(GC)
Packaging
25g
Price
$94
Updated
2025/07/31
TCI Chemical
Product number
C0789
Product name
cis-1,4-Cyclohexanedicarboxylic Acid
Purity
>90.0%(GC)
Packaging
100g
Price
$257
Updated
2025/07/31
TRC
Product number
C475840
Product name
cis-1,2-Cyclohexanedicarboxylic Acid
Packaging
250mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK145521
Product name
cis-1,4-Cyclohexanedicarboxylic Acid
Purity
90%
Packaging
5g
Price
$108
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC147028
Product name
cis-1,4-Cyclohexanedicarboxylic Acid
Packaging
50g
Price
$138
Updated
2021/12/16
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cis-1,4-Cyclohexanedicarboxybic acid Chemical Properties,Usage,Production

Definition

ChEBI: 1,4-cyclohexanedicarboxylic acid is a dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4.

Synthesis

100-21-0

619-81-8

The general procedure for synthesizing cis-1,4-cyclohexanedicarboxylic acid from terephthalic acid was as follows: 200 g of terephthalic acid, 15 g of the Pd-Pt/C catalyst of Examples 1 to 14 and 1000 g of water were added to an autoclave, and stirring was initiated. The reaction system was first purged with nitrogen three times, followed by hydrogen replacement three times. The hydrogen pressure was adjusted to 4 MPa, the reaction temperature was maintained at 200°C, and hydrogen was continuously supplied under this condition for 3 hours. At the end of the reaction, the catalyst was removed by filtration while hot. The filtrate was cooled and filtered again to collect the filter cake. The filter cake was dried at 120°C to obtain the solid product. The solid product was analyzed by liquid chromatography to determine the contents of 1,4-cyclohexanedicarboxylic acid and trans-1,4-cyclohexanedicarboxylic acid therein, from which the yield of 1,4-cyclohexanedicarboxylic acid and the selectivity of trans-1,4-cyclohexanedicarboxylic acid were calculated, and the specific results are listed in Table 2.

References

[1] Patent: CN103769089, 2016, B. Location in patent: Paragraph 0029; 0030
[2] RSC Advances, 2017, vol. 7, # 30, p. 18178 - 18188
[3] Patent: CN105237341, 2016, A. Location in patent: Paragraph 0014
[4] Patent: KR2017/36493, 2017, A. Location in patent: Paragraph 0057; 0058; 0059
[5] Patent: KR2018/35585, 2018, A. Location in patent: Paragraph 0117-0121; 0145; 0146

cis-1,4-Cyclohexanedicarboxybic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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cis-1,4-Cyclohexanedicarboxybic acid Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from cis-1,4-Cyclohexanedicarboxybic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
cis-1,4-Cyclohexanedicarboxybic acid 619-81-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000tons
Release date
2025-08-13
Career Henan Chemical Co
Product
cis-1,4-Cyclohexanedicarboxybic acid 619-81-8
Price
US $1.00/KG
Min. Order
1KG
Purity
85.0-99.8%
Supply Ability
20tons
Release date
2020-01-08

619-81-8, cis-1,4-Cyclohexanedicarboxybic acidRelated Search:


  • 1,4-Cyclohexanedicarboxylic acid, cis-
  • CIS-HEXAHYDROTEREPHTHALIC ACID
  • CIS-1,4-CYCLOHEXANEDICARBOXYBIC ACID
  • CIS-1,4-CYCLOHEXANEDICARBOXYLIC ACID
  • Cyclohexanedicarboxylicacid
  • cis-Cyclohexane-1,4-dicarboxylic acid
  • cis-1,4-Cyclohexanedicarboxylic Acid &gt
  • Cis-1,4-CyclohexanedicarboxylicAci
  • rac-(1s,4s)-cyclohexane-1,4-dicarboxylic acid
  • 619-81-8
  • 4-Substituted Cyclohexanecarboxylic Acids
  • chiral
  • 4-Substituted Cyclohexanecarboxylic Acids