gardneramine
- Product Name
- gardneramine
- CAS No.
- 34274-91-4
- Chemical Name
- gardneramine
- Synonyms
- gardneramine;1,2-Didehydo-2-deoxo-17-deoxy-2,17-epoxgardneramine oxindole;1,2-Didehydro-2-deoxo-17-deoxy-2,17-epoxygardneramine oxindole;4,1,11b-Ethanylylidene-2H-pyrido[2',3':5,6]oxepino[2,3-b]indole, 3,4,4a,5,12,12a-hexahydro-8,10,11-trimethoxy-3-(2-methoxyethylidene)-, (1R,3Z,4R,4aS,11bR,12aS,13S)-
- CBNumber
- CB71385671
- Molecular Formula
- C23H28N2O5
- Formula Weight
- 412.483
- MOL File
- 34274-91-4.mol
gardneramine Property
- Melting point:
- 133-134 °C
- Boiling point:
- 570.3±60.0 °C(Predicted)
- Density
- 1.46±0.1 g/cm3(Predicted)
- pka
- 8.59±0.20(Predicted)
N-Bromosuccinimide Price
- Product number
- INB0001908
- Product name
- GARDNERAMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.04
- Updated
- 2021/12/16
- Product number
- CFN98447
- Product name
- Gardneramine
- Packaging
- 5mg
- Price
- $653
- Updated
- 2021/12/16
gardneramine Chemical Properties,Usage,Production
Uses
Gardneramine is an orally active alkaloid that acts like papaverine. Gardneramine has peripheral vascular diastolic effect, direct inhibition on myocardium and central inhibition. Gardneramine showed antihypertensive, vasodilatation and atrial inhibition effects in rabbit, dog and guinea pig models, respectively. Gardneramine also inhibits the movement of smooth muscle organs such as the stomach and intestines[1].
Definition
ChEBI: A natural product found in Gardneria ovata.
in vivo
Gardneramine (4 mg/kg; i.v.; single dose) leads to a decrease in blood pressure in rabbits (up to 36.6%)[1].
Gardneramine (0.2 mg/kg, 0.4 mg/kg; i.a.; single dose) increases blood flow rate and produces vasodilation in the hind limbs of dogs[1].
Gardneramine (20 mg/kg, 40 mg/kg, and 80 mg/kg; i.p.; single dose) inhibits the movement of smooth muscle organs such as the stomach and intestines in mice[1].
Gardneramine (20 mg/kg; p.o.; single dose) mice were treated with small intestine removal, showing relaxation and slight inhibition of stress ion production[1].
References
[1] Harada M, et al. [Pharmacological studies on gardneria alkaloids. II. Peripheral effects (effects on circulatory and digestive systems)]. Yakugaku Zasshi. 1972 Dec;92(12):1540-6. Japanese. DOI:10.1248/yakushi1947.92.12_1540
gardneramine Preparation Products And Raw materials
Raw materials
Preparation Products
gardneramine Suppliers
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6003
- Advantage
- 61
- Tel
- 0871-65217109 13211707573;
- Fax
- 0871-65215563
- y.liu@mail.biobiopha.com
- Country
- China
- ProdList
- 5653
- Advantage
- 65
- Tel
- 028-81700200 18116577057
- Fax
- 028-81705658
- 3003855609@qq.com
- Country
- China
- ProdList
- 7778
- Advantage
- 56
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 18607101326 15172504745
- Fax
- +86-27-84254680
- aileen@chemfaces.com
- Country
- China
- ProdList
- 6905
- Advantage
- 55
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8447
- Advantage
- 60
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 028-028-85370565-229-229 18080489829
- 18080489829@163.com
- Country
- China
- ProdList
- 8250
- Advantage
- 60
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 18871490254
- Fax
- 027-59599243
- linda@hubeijusheng.com
- Country
- CHINA
- ProdList
- 28172
- Advantage
- 58
View Lastest Price from gardneramine manufacturers
- Product
- gardneramine 34274-91-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-27