galgravin
- Product Name
- galgravin
- CAS No.
- 528-63-2
- Chemical Name
- galgravin
- Synonyms
- galgravin;(±)-Galgravin;galgravin USP/EP/BP;Galgravin, 10 mM in DMSO;inhibit,Inhibitor,Apoptosis,Galgravin;(2S,3S,4R,5R)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane;rel-(2R,3R,4S,5S)-2,5-Bis(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran;Furan, 2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-, (2R,3R,4S,5S)-rel-
- CBNumber
- CB71393726
- Molecular Formula
- C22H28O5
- Formula Weight
- 372.45
- MOL File
- 528-63-2.mol
galgravin Property
- Melting point:
- 139-140 °C(Solv: methanol (67-56-1))
- Boiling point:
- 479.1±45.0 °C(Predicted)
- Density
- 1.082±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble
- form
- A solid
N-Bromosuccinimide Price
- Product number
- 300291
- Product name
- Galgravin
- Packaging
- 10mg
- Price
- $575
- Updated
- 2021/12/16
- Product number
- SY232804
- Product name
- (±)-Galgravin
- Packaging
- 10mg
- Price
- $638.18
- Updated
- 2021/12/16
galgravin Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Heather vine.
Uses
Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].
Definition
ChEBI: Galgravin is a member of the class of aryltetrahydrofurans carrying two 3,4-dimethoxyphenyl substituents at positions 2 and 5 as well as two methyl groups at positions 3 and 4. It has a role as a bone density conservation agent, a neuroprotective agent, a platelet aggregation inhibitor and a plant metabolite. It is an aryltetrahydrofuran, a dimethoxybenzene, a ring assembly and a lignan.
References
[1] da Silva Filho AA, et al. Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats. J Pharm Pharmacol. 2004 Sep;56(9):1179-84. DOI:10.1211/0022357044058
[2] Ponci V, et al. Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells. Molecules. 2015 Jul 15;20(7):12757-68. DOI:10.3390/molecules200712757
galgravin Preparation Products And Raw materials
Raw materials
Preparation Products
galgravin Suppliers
- Tel
- +86-028-82633397 18982077548
- Fax
- +86-28-82633165
- cwb1@biopurify.cn
- Country
- China
- ProdList
- 2376
- Advantage
- 60
- Tel
- 021-51320588
- Fax
- 0086-21-51320502
- tauto@tautobiotech.com
- Country
- China
- ProdList
- 3988
- Advantage
- 66
- Tel
- 2355253622; 18981954830
- Fax
- 086-28-85377358
- 2355253622@qq.com;
- Country
- China
- ProdList
- 1103
- Advantage
- 58
- Tel
- 18607101326 15172504745
- Fax
- +86-27-84254680
- aileen@chemfaces.com
- Country
- China
- ProdList
- 6905
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 021-36031160 13311776681
- 3338195766@QQ.com
- Country
- China
- ProdList
- 5093
- Advantage
- 55
- Tel
- 021-69955236-807 13918189704
- Fax
- 021-65211385
- chinaruji@chinaruji.com
- Country
- China
- ProdList
- 5095
- Advantage
- 55
- Tel
- 028-028-85370565-229-229 18080489829
- 18080489829@163.com
- Country
- China
- ProdList
- 8250
- Advantage
- 60
- Tel
- 028-85142057, 18030712385
- Fax
- 028-85142057 QQ:3591697873
- sales@alfabiotech.com
- Country
- China
- ProdList
- 1925
- Advantage
- 58