ChemicalBook > CAS DataBase List > Flavanomarein

Flavanomarein

Product Name: Flavanomarein
CAS No.: 577-38-8
Chemical Name: Flavanomarein
Synonyms: FLAVANOMAREIN;FLAVANOMAREIN hplc;TRIHYDROXYFLAVANONE;ISOOKANIN-7-GLUCOSIDE;FLAVANOMAREIN WITH HPLC;ISOOKANIN-7-O-GLUCOSIDE;FLAVANOMAREIN USP/EP/BP;Flavanomarein, 10 mM in DMSO;7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE;3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE
CBNumber: CB7144422
Molecular Formula: C21H22O11
Formula Weight: 450.39
MOL File: 577-38-8.mol

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Flavanomarein Property

Melting point:: 243-246°C
Boiling point:: 818.2±65.0 °C(Predicted)
Density: 1.665±0.06 g/cm3(Predicted)
pka: 7.58±0.40(Predicted)
form: Solid
color: White to off-white
InChIKey: DGGOLFCPSUVVHX-SKKRAFSDNA-N
SMILES: C12C(O)=C(C=CC=1C(=O)C[C@@H](C1C=CC(O)=C(O)C=1)O2)O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O |&1:10,21,22,24,25,27,r|
LogP: -1.080 (est)

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Safety

Hazard Codes: Xi

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

Arctom

Product number: CFN91006
Product name: Flavanomarein
Packaging: 5mg
Price: $328
Updated: 2021/12/16

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Flavanomarein Chemical Properties,Usage,Production

Chemical Properties

Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein.

Uses

Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.
Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase

Flavanomarein Preparation Products And Raw materials

Raw materials

Preparation Products

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577-38-8, FlavanomareinRelated Search:

OKANIN THEVETIN Inosine XANTHOSINE DIHYDRATE MAREIN 7-METHOXYFLAVANONE 3'-HYDROXYFLAVANONE 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-METHOXY- Liquiritigenin 7,8-DIHYDROXYFLAVANONE Butin 4'-O-METHYLDAVIDIGENIN Flavanomarein CHEMBRDG-BB 6367761 FLAVANOMAREIN(SH) 2,3-Dihydroxy-4-Ethoxy-Benzaldehyde 3-(4-PROPOXY-PHENYL)-PROPAN-1-OL 2',3',4',3,4-PENTAHYDROXYDIHYDROCHALCONE

TRIHYDROXYFLAVANONE

7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE

FLAVANOMAREIN

ISOOKANIN-7-GLUCOSIDE

ISOOKANIN-7-O-GLUCOSIDE

(S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one

FLAVANOMAREIN WITH HPLC

FLAVANOMAREIN hplc

3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE

(S)-2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one

(2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one

(2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-chroman-4-one

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-, (2S)-

FLAVANOMAREIN USP/EP/BP

antioxidative,PI3K,antihypertensive,Smad,anti-hyperlipidemic,Flavanomarein,6-hydroxydopamine,NF-κB,TGF-β1,diabetic,nephropathy,inhibit,Inhibitor,AKT,Syk,antidiabetic

(S)-2-(3,4-Dihydroxyphenyl)-8-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one

Flavanomarein, 10 mM in DMSO

(S)-2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one

577-38-8

reagent

Flavanones