ChemicalBook > CAS DataBase List > Flavanomarein

Flavanomarein

Product Name
Flavanomarein
CAS No.
577-38-8
Chemical Name
Flavanomarein
Synonyms
FLAVANOMAREIN;FLAVANOMAREIN hplc;TRIHYDROXYFLAVANONE;ISOOKANIN-7-GLUCOSIDE;FLAVANOMAREIN WITH HPLC;ISOOKANIN-7-O-GLUCOSIDE;FLAVANOMAREIN USP/EP/BP;7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE;3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE;(S)-2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
CBNumber
CB7144422
Molecular Formula
C21H22O11
Formula Weight
450.39
MOL File
577-38-8.mol
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Flavanomarein Property

Melting point:
243-246°C
Boiling point:
818.2±65.0 °C(Predicted)
Density 
1.665±0.06 g/cm3(Predicted)
pka
7.58±0.40(Predicted)
form 
Solid
color 
White to off-white
LogP
-1.080 (est)
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Safety

Hazard Codes 
Xi
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

Arctom
Product number
CFN91006
Product name
Flavanomarein
Packaging
5mg
Price
$328
Updated
2021/12/16
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Flavanomarein Chemical Properties,Usage,Production

Chemical Properties

Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein.

Uses

Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.
Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase

Flavanomarein Preparation Products And Raw materials

Raw materials

Preparation Products

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577-38-8, FlavanomareinRelated Search:


  • TRIHYDROXYFLAVANONE
  • 7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE
  • FLAVANOMAREIN
  • ISOOKANIN-7-GLUCOSIDE
  • ISOOKANIN-7-O-GLUCOSIDE
  • (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
  • FLAVANOMAREIN WITH HPLC
  • FLAVANOMAREIN hplc
  • 3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE
  • (S)-2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
  • (2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
  • (2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-chroman-4-one
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-, (2S)-
  • FLAVANOMAREIN USP/EP/BP
  • antioxidative,PI3K,antihypertensive,Smad,anti-hyperlipidemic,Flavanomarein,6-hydroxydopamine,NF-κB,TGF-β1,diabetic,nephropathy,inhibit,Inhibitor,AKT,Syk,antidiabetic
  • (S)-2-(3,4-Dihydroxyphenyl)-8-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one
  • 577-38-8
  • reagent
  • Flavanones